Showing 1–25 of 200 documents
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Amanda Mabhula
Tuberculosis (TB) is the leading cause of death due to a single infectious disease and remains a major threat to global public health. The increasing emergence of multi-drug resistance to current anti-TB drugs, exacerbated by the long treatment duration, highlights the need for n…
幸作 小宮
…e advanced age is a main prognostic factor in patients with tuberculosis, the factors that specifically affect tuberculosis-related death are unclear because elderly people are at a risk for other age-related lethal diseases.We hypothesized that performance status, a prognostic f…
Darja Sadovska
Despite significant advancements in tuberculosis (TB) diagnostics, treatment, and prevention, the disease remains a major global public health challenge, with only limited reductions in incidence rates observed. In recent years, whole-genome sequencing (WGS) of Mycobacterium tube…
Darja Sadovska
Despite significant advancements in tuberculosis (TB) diagnostics, treatment, and prevention, the disease remains a major global public health challenge, with only limited reductions in incidence rates observed. In recent years, whole-genome sequencing (WGS) of Mycobacterium tube…
Nirajan Niroula
The study of tuberculosis (TB) pathogenesis has benefitted from the use of animal models like mice, guinea pigs, rabbits, and non-human primates (NHPs). Except for NHP, most animal models have limitations mimicking different aspects of human TB. We propose that the domestic pig, …
Ann Mary Joyce
…rs ago, in 1993, the World Health Organization had declared tuberculosis (TB), a global health emergency due to its severity and consequences. An age-old disease, TB still remains a major public health problem reaching epidemic proportions in many developing countries, with a thi…
Avery Calkins
Between 1900 and 1940, tuberculosis moved from being the second highest cause of death in the United States to no longer being a leading cause of death. The historical causes of the decline in tuberculosis thus remain unclear. This paper examines the role of public health demonst…
Bwarenaba B Kautu
Tuberculosis (TB) is a deadly infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis). Currently, it is the leading infectious disease killer in the world ranking above HIV/AIDS. Furthermore, the continued emergence and spread of drug-resistant forms of TB are i…
Happy Ary Satyani, Krit Pongpirul
Tuberculosis (TB) is one of the 13th leading causes of death from a single infectious agent in the world in 2019. Some of the factors that influence the tuberculosis incident in the world are caused by undernourishment, HIV infection, alcohol use disorders, smoking, and diabetes.…
Yassir Adam Shuaib
The Sudan is a high tuberculosis (TB) burden country (i.e. 77 per 100,000 population). Specifically, the eastern part of the country is endemic with high incidence rates of TB reaching up to 275 per 100,000 population during the past decade. Prevalence of Mycobacterium tuberculos…
Hanouf Niyazi
…ons of current and new drug regimens and the response of M. tuberculosis to treatment are complicated and time consuming. Other issues include the need for accurate and early detection, drug resistance screening and follow-up measures to ensure treatment completion as intended. T…
GODFREY ADEBASIKU, Julius Oluka
Background Tuberculosis is an infectious airborne bacterial disease. The study aims to assess the factors contributing to non-adherence to Ani-Tuberculosis drugs among Tuberculosis Patients. Methodology A cross-sectional study was designed at Arua Regional Referral Hospital in th…
Abdelgawad, Noha
Tuberculosis (TB) is the primary cause of death from a single infectious agent worldwide. During the coronavirus disease (COVID-19) pandemic, TB briefly fell to second place, but it has now regained its position as the top infectious killer. It is caused by Mycobacterium tubercul…
H M Rickman
Tuberculosis (TB) remains the leading infectious cause of mortality globally. However, significant reductions have been achieved, particularly in high-burden urban settings in southern Africa, and transmission is concentrating in vulnerable populations and neighbourhoods. This he…
Bei Shi Lee
Tuberculosis is a deadly communicable disease caused by Mycobacterium tuberculosis. Recent advances have revealed that the pathogen’s energy metabolism is particularly vulnerable to chemical inhibition. For instance, Telacebec (Q203), which targets the respiratory terminal oxidas…
Alvaro Schwalb Calderón
…de la población mundial ha sido infectada por Mycobacterium tuberculosis (Mtb), agente causante de la tuberculosis (TB). A pesar de los esfuerzos actuales, la reducción de la TB avanza lentamente. Esta tesis busca generar estimaciones precisas de la carga de infección viable por …
Haider Abdulrazzaq Abed Al‐Darraji
Background: \nPoorly managed tuberculosis (TB) control programmes in prisons have detrimental health consequences, placing prisoners at an increased risk for TB morbidity and mortality. This situation could further fuel the TB epidemic in the general population when prisoners…
Abdulloh Mazalan
…as to compare the effectiveness between the newly developed Tuberculosis Contact Reminder System (TCRS) and current system in improving the screening uptake and retention rate in the subsequent screening among TB contacts, staffs’ satisfaction and description of implementation co…
Percis Phindile Khumalo
… therapy and \nlimiting the emergence of drug resistant tuberculosis. However, the prevalence of TB \ncontinues to soar despite the available comprehensive treatment. The study \ninvestigated determinants of adherence to TB treatment and the strategies to enhance …
Mosunmula Oluwaseun Iwakun
A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA NIGERIA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OFTHE DOCTOR OF PHILOSOPHY IN MICROBIOLOGY DEPARTMENT OF MICROBIOLOGY, FACULTY OF LIFE SCIENCES, AHMADU BELLO UNIVERSITY, ZARI…
Nicholas Winters
La tuberculose est l'une des plus anciennes maladies infectieuses documentées et reste à ce jour un fardeau important pour la santé mondiale. On estime qu'un quart de la population mondiale vit avec une infection tuberculeuse et qu'environ 5 à 10 % d'entre eux développeront une t…
Victor Williams
…, several people continue to die from diabetes mellitus and tuberculosis annually. Current estimates show that low-resource settings, particularly Sub-Saharan Africa, have the highest incidence of new tuberculosis cases, with a year-on-year increase in diabetes mellitus cases. Fu…
Henock Bekele Keto
…s factors associated with the development of drug resistant tuberculosis in Ethiopia. \nDESIGN: A quantitative case-control study was conducted to determine if there were any significant differences in prevalence of pre-defined factors between cases and controls. \nMETHOD…
Erick Wekesa Bunyasi
…lthough adolescents have the highest force of Mycobacterium tuberculosis infection1 and rapidly increasing burden of tuberculosis (TB) disease through 10–19 years of age,2 there are few studies on adolescent Mycobacterium tuberculosis infection, transmission, and TB disease in th…
PHILIP MANGWI, DR. NIWAGIIRA MULODOKAYI
… of the study It was for the prevalence and risk factors of tuberculosis among patients attending to Arua Regional Referral Hospital, Arua district. The specific objectives To establish the prevalence of Tuberculosis among patients seen at Arua Regional Referral Hospital, individ…