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Ian Sanne, Yara Voss De Lima, Antonia Barnard, Colin Menezes, Liesl Page‐Shipp, et al.
ObjectiveTo assess the outcomes of linkage to TB and HIV care and identify risk factors for poor referral outcomes.DesignCohort study of TB patients diagnosed at an urban hospital.MethodsLinkage to care was determined by review of clinic files, national death register, and teleph…
Xie K, Zhang Y, Zhang M, Wu H, Zheng L, et al.
…e disease. VDD is also associated with an increased risk of HIV-related comorbidities and mortality, and patients have a tendency to develop active tuberculosis compared to those with latent tuberculosis infection. Vitamin D supplementation may modulate HIV replication, improve T…
Reid VA, Ramos EI, Veerapandian R, Carmona A, Gadad SS, et al.
…ulosis (TB) is the leading cause of death among people with HIV-1 infection. To improve the diagnosis and treatment of HIV-TB patients, it is important to understand the mechanisms underlying these conditions. Here, we used an integrated genomics approach to analyze and determine…
Anne Detjen, Shaffiq Essajee, Malgorzata Grzemska, Ben J. Marais
…novel partnerships for child health and development.•TB and HIV partners need to align better and jointly formulate strategies to scale up pediatric TB and HIV in an integrated MNCH and PHC context.•Integrated, family-centered approaches, implemented at the community and primary …
Renu Kumari, Priyamvada Roy, Shalini Malhotra, Ulka Kamble, Nirmaljit Kaur
… counts in patients with both human immunodeficiency virus (HIV) and tuberculosis (TB) infections compared to HIV-positive patients without TB following six months of treatment with anti-tuberculosis therapy (ATT) and antiretroviral therapy (ART). This study aims to assess absolu…
Rao D, Venkataswamy MM, Vasanthapuram R, Satishchandra P, Desai A
Background Neurotuberculosis is one of the commonest HIV associated opportunistic infections of the central nervous system in India. HIV-TB coinfection may lead to altered frequencies of T cells, thereby influencing the course and progression of the disease. Methods We examined t…
Varghese GM, Turaka VP, Janardhanan J, Yadav S, Lakshmi KM, et al.
…e levels of siderocalin in patients with TB with or without HIV infection compared to controls. Methods Siderocalin levels were tested using a neutrophil gelatinase-associated lipocalin (NGAL) ELISA kit in four populations: HIV-infected patients with TB (HIV pos , TB pos ), non-H…
Wang Y, Jing W, Liu J, Liu M
Background People living with human immunodeficiency virus (HIV) are more likely to develop tuberculosis (TB), and their co-infection (HIV-TB) increases the risk of death. We aimed to describe the global trends, regional differences and age distribution of HIV-TB. Methods Annual …
Vanphanom Sychareun, Viengnakhone Vongxay, Souksamone Thongmyxay, Kongmany Chaleunvong, Jo Durham, et al.
…nges in combating the treatable and preventable diseases of HIV/AIDS, tuberculosis (TB), and malaria among priority groups. One priority group are pregnant women. Given increased availability of diagnosis and treatment for these diseases, understanding community knowledge and acc…
Mitiku AM, Asfaw GZ, Tsegay HT, Zewdie BY, Tesfay AM
…kground Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) are global public health problems. TB and HIV diagnostic services linkage is imperative for the fight against the two diseases. Objective To assess the diagnostic service linkage and testing of TB-HIV diagnostic ser…
Li Q, Wang C, Gou J, Kitanovski S, Tang X, et al.
…eading cause of mortality among individuals coinfected with HIV, characterized by progressive pulmonary inflammation. Despite TB's hallmark being focal granulomatous lung lesions, our understanding of the histopathological features and regulation of inflammation in HIV & TB coinf…
Geetanjali Chander, Nishi Suryavanshi, Nikhil Gupte, Gauri Dhumal, Shatabdi Bagchi, et al.
…ases globally, with approximately 48,000 among persons with HIV (PWH). Unhealthy alcohol use can worsen the health of people who have TB or HIV and those who have both TB and HIV. Behavioral interventions that target alcohol use and are integrated into TB and HIV care may lead to…
Damhorst G, Keener M, Timme E, Venkat H, DeStephens R
… factors for tuberculosis (TB) in the United States include HIV-positive status, birth outside of the United States, incarceration and homelessness. Despite advances in antiretroviral therapy (ART) and declining HIV-TB comorbidity, TB remains an important opportunistic infection …
Md Abdul Kuddus, Sazia Khatun Tithi, Anip Kumar Paul, Thitiya Theparod
…tion of Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) remains a significant public health challenge both in Thailand and globally. This dual burden exacerbates disease severity, complicates treatment strategies, and increases mortality rates. In this study, we develope…
Tamene W, Abebe M, Wassie L, Mollalign H, Bauer K, et al.
…tion with PD1 is implicated in immune dysfunction in TB and HIV. The expression of PDL1 on multiple subsets of monocytes as well as their associations with cytokines and microbial products have not been well studied. Method HIV (TB-HIV+), TB (TB+HIV-) and TB/HIV co-infected (TB+H…
John C. Mgogwe, Jaffu Otheniel Chilongola
…nt tuberculosis (MDR-TB) with human immunodeficiency virus (HIV) immunologic state which is marked by chemokine and cytokine distortion is indicated by boosting the defense stimulation to a patient. The effect of coexisting infections on the MDR-TB patient with HIV is still not f…
Li L, Abudureheman Z, Zhong X, Gong H, Yang F, et al.
…nts who are coinfected with human immunodeficiency virus 1 (HIV) and Mycobacterium tuberculosis (TB) benefit from timely diagnosis and treatment. In the present study frequencies of CD3 + , CD4 + , and CD8 + T cells among peripheral blood mononuclear cells (PBMCs) of patients in …
Margherita Bracchi, Clare van Halsema, Frank A. Post, Funmi Awosusi, Alison Barbour, et al.
…helped transform the management of TB in people living with HIV. The overall purpose of these guidelines is to help physicians manage adults with tuberculosis (TB)/human immunodeficiency virus (HIV) co-infection. Recommendations for the treatment of TB in HIV-positive adults are …
Rupani MP, Vyas S, Shah IA
…etermine the association between catastrophic costs from TB-HIV and TB-diabetes care and unfavorable TB treatment outcomes. Methods We conducted a cohort study in Bhavnagar, India, from July 2019 to January 2021, involving 234 TB-HIV and 304 TB-diabetes patients. Catastrophic cos…
Zhang SX, Wang JC, Yang J, Lv S, Duan L, et al.
…ackground The co-infection of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) and tuberculosis (TB) poses a significant clinical challenge and is a major global public health issue. This study aims to elucidate the disease burden of HIV-TB co-infecti…
Mihir P. Rupani, Sheetal Vyas
…ctors of catastrophic costs due to TB among co-prevalent TB-HIV and TB-diabetes patients. Methods: We conducted a cross-sectional study among 234 patients co-affected with TB-HIV and 304 patients with TB-diabetes co-prevalence in the Bhavnagar region (western part of India). TB c…
Shun-Xian Zhang, Jin-Xin Zheng, Yu Wang, Wen-Wen Lv, Jian Yang, et al.
…e years (DALYs) for TB from 1990 to 2021. Over this period, HIV-negative TB showed a marked decline in ASIR (AAPC = -2.34%, 95% CI: -2.39, -2.28) and ASMR (AAPC = -0.56%, 95% CI: -0.62, -0.59). Specifically, drug-susceptible TB (DS-TB) showed reductions in both ASIR and ASMR, whi…
MacPherson P, Webb EL, Kamchedzera W, Joekes E, Mjoli G, et al.
Background Suboptimal tuberculosis (TB) diagnostics and HIV contribute to the high global burden of TB. We investigated costs and yield from systematic HIV-TB screening, including computer-aided digital chest X-ray (DCXR-CAD). Methods and findings In this open, three-arm randomis…
Gengiah S, Naidoo K, Mlobeli R, Tshabalala MF, Nunn AJ, et al.
Introduction In South Africa, mortality rates among HIV-TB coinfected patients are among the highest in the world. The key to reducing mortality is integrating HIV-TB services, however, a generalizable implementation method and package of tested change ideas to guide the scale-up…
Li L, Abudureheman Z, Zhong X, Gong H, Yangfan, et al.
…nts who are coinfected with human immunodeficiency virus 1 (HIV) and Mycobacterium tuberculosis (TB) benefit from timely diagnosis and treatment. In the present study frequencies of CD3⁺, CD4⁺, and CD8⁺ T cells among peripheral blood mononuclear cells (PBMCs) of patients in the K…