Showing 1–25 of 200 documents
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World Health Organization, University of California, San Francisco
Renu Kumari, Priyamvada Roy, Shalini Malhotra, Ulka Kamble, Nirmaljit Kaur
… counts in patients with both human immunodeficiency virus (HIV) and tuberculosis (TB) infections compared to HIV-positive patients without TB following six months of treatment with anti-tuberculosis therapy (ATT) and antiretroviral therapy (ART). This study aims to assess absolu…
Mohau S. Makatsa
… of the treatment is hampered by multidrug resistant TB and HIV infection. There is an urgent need for an effective TB vaccine to prevent ongoing transmission. The development of a new and efficacious TB vaccine will likely be dependent on our understanding of protective immunity…
Varghese GM, Turaka VP, Janardhanan J, Yadav S, Lakshmi KM, et al.
…e levels of siderocalin in patients with TB with or without HIV infection compared to controls. Methods Siderocalin levels were tested using a neutrophil gelatinase-associated lipocalin (NGAL) ELISA kit in four populations: HIV-infected patients with TB (HIV pos , TB pos ), non-H…
Rao D, Venkataswamy MM, Vasanthapuram R, Satishchandra P, Desai A
Background Neurotuberculosis is one of the commonest HIV associated opportunistic infections of the central nervous system in India. HIV-TB coinfection may lead to altered frequencies of T cells, thereby influencing the course and progression of the disease. Methods We examined t…
Reid VA, Ramos EI, Veerapandian R, Carmona A, Gadad SS, et al.
…ulosis (TB) is the leading cause of death among people with HIV-1 infection. To improve the diagnosis and treatment of HIV-TB patients, it is important to understand the mechanisms underlying these conditions. Here, we used an integrated genomics approach to analyze and determine…
Xie K, Zhang Y, Zhang M, Wu H, Zheng L, et al.
…e disease. VDD is also associated with an increased risk of HIV-related comorbidities and mortality, and patients have a tendency to develop active tuberculosis compared to those with latent tuberculosis infection. Vitamin D supplementation may modulate HIV replication, improve T…
Ian Sanne, Yara Voss De Lima, Antonia Barnard, Colin Menezes, Liesl Page‐Shipp, et al.
ObjectiveTo assess the outcomes of linkage to TB and HIV care and identify risk factors for poor referral outcomes.DesignCohort study of TB patients diagnosed at an urban hospital.MethodsLinkage to care was determined by review of clinic files, national death register, and teleph…
Andrine
… in the biofluids of people suffering with IPF, COPD and TB/HIV co-morbidity. The test could both be used for diagnostics and disease progression tracking.<br/><br/>Methods: The study consists of three parts; a COPD study, IPF study and TB/HIV study. For the IPF study 32 urine sa…
Amita Gupta, MD
…ases globally, with approximately 86,000 among persons with HIV (PWH). Unhealthy alcohol use can worsen the health of people who have Tuberculosis (TB), HIV and people who have both TB and HIV. Behavioral interventions that 1) target alcohol use and 2) are integrated into TB and …
Helen Ayles, Professor
Tuberculosis (TB) has overtaken HIV as the leading infectious cause of death worldwide and requires a major policy shift for it to be controlled in line with the WHO Stop-TB goal to "end TB". However, how to control TB at population level in the context of HIV, is unknown. Some o…
Kogieleum Naidoo, MBChB
…uth Africa, which is, to develop and test optimal models of HIV-TB service delivery that will enhance retention, adherence and coverage of HIV-TB co-infected patients. HIV and TB are highest in sub-Saharan Africa, a region with limited health budgets, infrastructure, human resour…
Anne Detjen, Shaffiq Essajee, Malgorzata Grzemska, Ben J. Marais
…novel partnerships for child health and development.•TB and HIV partners need to align better and jointly formulate strategies to scale up pediatric TB and HIV in an integrated MNCH and PHC context.•Integrated, family-centered approaches, implemented at the community and primary …
Zhang SX, Wang JC, Yang J, Lv S, Duan L, et al.
…ackground The co-infection of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) and tuberculosis (TB) poses a significant clinical challenge and is a major global public health issue. This study aims to elucidate the disease burden of HIV-TB co-infecti…
Institut National de la Santé Et de la Recherche Médicale, France
…tional PK study of anti-TB treatment nested in the TB-Speed HIV and TB-Speed SAM studies aiming at assessing the impact of malnutrition on PK of rifampicin, isoniazid, pyrazinamide, and ethambutol in TB-HIV co-infected children in Uganda and Zambia. Tuberculosis can worsen malnu…
Geetanjali Chander, Nishi Suryavanshi, Nikhil Gupte, Gauri Dhumal, Shatabdi Bagchi, et al.
…ases globally, with approximately 48,000 among persons with HIV (PWH). Unhealthy alcohol use can worsen the health of people who have TB or HIV and those who have both TB and HIV. Behavioral interventions that target alcohol use and are integrated into TB and HIV care may lead to…
Leslie A. Enane, Adam Leonard, Lameck Diero, Olivier Marcy, Marcel Yotebieng
…d the most common opportunistic infection among people with HIV, imposes a profound burden on adolescents and young adults (AYA, ages 10–24 years) [1]. Although preventable and curable, TB remains a leading cause of death for AYA in endemic settings, the predominant cause of morb…
Osei Bonsu E, Addo IY, Adjei BN, Alhassan MM, Nakua EK
…e, treatment outcomes and determinants of tuberculosis (TB)-HIV coinfection in Ghana. Study design A retrospective review of TB case register for Kwabre East Municipality was conducted for the period 2010-2020 to identify TB-HIV coinfections. Setting 462 patients with TB from fou…
Margherita Bracchi, Clare van Halsema, Frank A. Post, Funmi Awosusi, Alison Barbour, et al.
…helped transform the management of TB in people living with HIV. The overall purpose of these guidelines is to help physicians manage adults with tuberculosis (TB)/human immunodeficiency virus (HIV) co-infection. Recommendations for the treatment of TB in HIV-positive adults are …
Damhorst G, Keener M, Timme E, Venkat H, DeStephens R
… factors for tuberculosis (TB) in the United States include HIV-positive status, birth outside of the United States, incarceration and homelessness. Despite advances in antiretroviral therapy (ART) and declining HIV-TB comorbidity, TB remains an important opportunistic infection …
Elizabeth Corbett, MD, David Dowdy, MD. PhD, Lawrence Moulton, PhD
… algorithms for TB case detection on Tuberculosis (TB)- and HIV-related outcomes; (2) to compare the impact of using the routine screening and GeneXpert algorithms for exclusion of TB prior to initiation of IPT and ART on TB- and HIV-related outcomes; and (3) to assess the relati…
Mitiku AM, Asfaw GZ, Tsegay HT, Zewdie BY, Tesfay AM
…kground Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) are global public health problems. TB and HIV diagnostic services linkage is imperative for the fight against the two diseases. Objective To assess the diagnostic service linkage and testing of TB-HIV diagnostic ser…
Wang Y, Jing W, Liu J, Liu M
Background People living with human immunodeficiency virus (HIV) are more likely to develop tuberculosis (TB), and their co-infection (HIV-TB) increases the risk of death. We aimed to describe the global trends, regional differences and age distribution of HIV-TB. Methods Annual …
Vanphanom Sychareun, Viengnakhone Vongxay, Souksamone Thongmyxay, Kongmany Chaleunvong, Jo Durham, et al.
…nges in combating the treatable and preventable diseases of HIV/AIDS, tuberculosis (TB), and malaria among priority groups. One priority group are pregnant women. Given increased availability of diagnosis and treatment for these diseases, understanding community knowledge and acc…
Guita Amane, Paula Simbine, Pereira Zindoga, Algy Abdula, Miguelhete Lisboa
**BACKGROUND:** HIV testing among people with presumptive tuberculosis (PP-TB) represents a critical entry point for HIV diagnosis and care, especially in high-burden settings like Mozambique. However, systematic testing in this population remains suboptimal. This study assessed …