Pre-extensively Drug-Resistant Congenital Tuberculosis in an Extremely Premature Baby
Boast A, How JA, Lau C, Sett A, Gilby D, Burke A, McWhinney B, Wright C, et al. (13 authors)
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024-01
Abstract
We describe a case of congenital tuberculosis in an extremely premature baby, with rapid molecular detection of a pre-extensively drug-resistant (XDR) pattern of drug resistance. The baby was treated successfully with a regimen including bedaquline and delamanid, drugs not previously described in the treatment of congenital tuberculosis (TB).
MeSH terms
- Humans
- Mycobacterium tuberculosis
- Tuberculosis, Multidrug-Resistant
- Tuberculosis, Pulmonary
- Antitubercular Agents
- Microbial Sensitivity Tests
- Drug Resistance, Multiple, Bacterial
- Extensively Drug-Resistant Tuberculosis