Showing 176–200 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
J. McIntosh, Nikkiah Forbes, Kevin Moss, Morton Anthony C Frankson
…tuberculosis in the Bahamas difficult such as high rates of HIV infection and immigrants migrating from countries with high TB prevalence. In understanding the epidemiology and risk factors of TB cases in the Bahamas, the development of protocols can improve screening procedures …
Sarah A.E. Rupprechter, Derek J. Sloan, Wilna Oosthuyzen, Till T. Bachmann, Adam T. Hill, et al.
…lTrials.gov Identifier: NCT03211208). African patients with HIV-TB coinfection, receiving anti-TB and anti-retroviral therapy (ART), were recruited at the Infectious Diseases Institute, Kampala, Uganda (SAEFRIF-NCT03982277). Serial blood samples, demographic and clinical data wer…
Sophie Forsyth, Tolulope Subuloluwa, Myat Lwin, Jessica Henderson Daniel
<h3>Introduction</h3> 2018 BHIVA Tuberculosis (TB) guidelines recommend testing people living with HIV (PLWH) from countries with high and medium TB incidence for LTBI and from low-incidence countries if they have additional TB risk factors. We had not yet introduced this in our …
Sarah A.E. Rupprechter, Derek J. Sloan, Wilna Oosthuyzen, Till T. Bachmann, Adam T. Hill, et al.
…Trials.gov Identifier: NCT03211208 ). African patients with HIV-TB coinfection, receiving anti-TB and anti-retroviral therapy (ART), were recruited at the Infectious Diseases Institute, Kampala, Uganda (SAEFRIF - NCT03982277 ). Serial blood samples, demographic and clinical data …
Riou C, Du Bruyn E, Ruzive S, Goliath RT, Lindestam Arlehamn CS, et al.
…ells in whole blood from 161 participants of varying TB and HIV status. TB disease extent was graded as a continuum using the Xpert ct value, C-reactive protein, Timika radiographic score and monocyte/lymphocyte ratio. Results The phenotypic profile of Mtb-specific CD4 T cells pr…
Day CL, Willis F, Staitieh BS, Campbell A, Martinson N, et al.
…se of death among people with human immunodeficiency virus (HIV), the impact of HIV infection on Mtb-specific immune responses remains unclear. In this cross-sectional study of TB-exposed household contacts with and without HIV, we collected remaining supernatant from interferon-…
Manish Pareek
…d risk of infectious diseases, including tuberculosis (TB), HIV, hepatitis B and hepatitis C, and have poorer outcomes. Early diagnosis and management of these infections can reduce morbidity, mortality and onward transmission and is supported by national guidelines. To date, scr…
Pareek M, Eborall HC, Wobi F, Ellis KS, Kontopantelis E, et al.
…d risk of infectious diseases, including tuberculosis (TB), HIV, hepatitis B and hepatitis C, and have poorer outcomes. Early diagnosis and management of these infections can reduce morbidity, mortality and onward transmission and is supported by national guidelines. To date, scr…
Sophia B Siddiqui, M.D.
… physical examination and blood tests, including a test for HIV. People in Mali, West Africa, and in local health clinics in the United States may participate. At the start of the study, participants have blood tests and a tuberculin skin test (PPD test), which indicates whether…
Gudeta Imana Jaleta, Vinodhini Rajamanickam, Kifle Woldemichael
…nfection and a common cause of death for people living with HIV (PLHIV). The influence of TB and HIV infection has enhanced the magnitude of both epidemics. Several clinical interventions recommended early diagnosis in PLHIV and treating latent TB infection (LTBI) with Isoniazid …
Adong J, Fatch R, Emenyonu N, Muyindike W, Ngabirano C, et al.
Background HIV/AIDS is now a manageable chronic illness owing to effective antiretroviral therapy (ART), which involves routine follow-up care, including regular physical visits to the clinic. In the recent past, and in wake of the COVID-19 pandemic, there has been increased need…
PENTA Foundation
…orts) of children living with human immunodeficiency virus (HIV) and other infections over time, to monitor their long-term health. Some of these infections are rare: for example, few children in Western Europe are living with HIV, so the studies often have fairly small numbers o…
Catherine M. Stein, Penelope Benchek, Jacquelaine Bartlett, Robert P. Igo, Rafal S. Sobota, et al.
…infected with both TB and the human immunodeficiency virus (HIV), the risk of active disease is 10% or more per year. Previously, we identified in a genome-wide association study a region on chromosome 5 that was associated with resistance to TB. This region included epigenetic m…
Kaplan SR, Escudero JN, Mecha J, Richardson BA, Maleche-Obimbo E, et al.
Background HIV and pregnancy may affect latent TB infection (LTBI) diagnostics. Tuberculin skin test (TST) and newer generation QuantiFERON-TB Gold Plus (QFT-Plus) evaluations in pregnant women living with HIV (WLHIV) and without HIV are lacking. Methods In this cross-sectional s…
… LTBI (Latent Tuberculosis Infection) in people living with HIV, household contacts of people with active TB, other groups at risk of developing TB, and for LTBI testing. The consolidated guidelines are expected to provide the basis and rationale for the development of national g…
Deepak V. Sawant, Shivaji H. Pawar
…ions, where diagnosing of latent TB, drug-resistant TB, and HIV co-infected, pediatric TB remains still a challenge. There are so many low sensitive conventional TB diagnosis methods are available which are responsible for delay in early-stage TB diagnosis. There is an urgent dem…
Girmay G, Kiflie A, Alem M, Lemma M, Bewket G
Tuberculosis (TB) and HIV co-infections are extensively overlapping, especially in developing countries. HIV infection is known as a major risk factor for the reactivation of latent TB into active TB. Although not fully understood and needs further study, HIV infection might enha…
Siqueira Santos LF, Vilarino Carneiro PH, Alves de Oliveira Serra MA, Hunaldo Dos Santos L, Pinto de Andrade HL, et al.
… analyze the prevalence trend, spatial distribution, and TB-HIV co-infection-associated factors in an endemic scenario for TB in Northeastern Brazil. Methods An ecological and temporal series study was conducted based on secondary data obtained from the Brazilian Notifiable Disea…
Rebecca F Baggaley, Christopher A Martin, Helen C Eborall, Marjan Gohar, Kashif Aziz, et al.
…is (TB) with an interferon gamma release assay (IGRA) test, HIV, hepatitis B virus (HBV, using hepatitis B surface antigen testing) and hepatitis C virus (HCV, using antibody testing with confirmatory PCR test) infection when patients first registered with general practices (GPs)…
Charisse Mandimika, Gerald Friedland
…vances and challenges in the prevention and treatment of TB/HIV disease. Drug-susceptible and drug-resistant tuberculosis (TB) and human immunodeficiency virus (HIV) epidemics are a consequence of reactivation of latent TB infection (LTBI), treatment-related amplification of TB r…
Zeeb M, Tepekule B, Kusejko K, Reiber C, Kälin M, et al.
Background People with human immunodeficiency virus type 1 (HIV-1) (PWH) are frequently coinfected with Mycobacterium tuberculosis (MTB) and at risk for progressing from asymptomatic latent TB infection (LTBI) to active tuberculosis (TB). LTBI testing and preventive treatment (TB…
Adriana Weinberg, Lisa Aaron, Grace Montepiedra, Timothy R. Sterling, Nahida Chaktoura, et al.
…245) CD4+ cells/µL, on ART, including 63% with undetectable HIV plasma RNA, 284/944 (30%) were QGIT+ AP, 215/862 (25%) at L&D and 246/764 (32%) PP (P < 0.001), while 127 (15%) were TST+ at L&D and 126 (17%) PP. QGIT was more likely positive than TST at L&D (Odds ra…
Mohau S. Makatsa, F. Millicent A. Omondi, Rubina Bunjun, Robert J. Wilkinson, Catherine Riou, et al.
… TB disease, with and without human immunodeficiency virus (HIV)-1 infection. We investigated the functional properties (IFN-γ, IL-22 and IL-17 production), memory differentiation (CD45RA, CD27 and CCR7) and activation profile (HLA-DR) of Mtb-specific CD4+ T cells. In HIV-uninfec…
Kapata N, Tembo J, Mwaba P, Nabyonga-Orem J, Ntoumi F, et al.
…of undetected TB cases, particularly among individuals with HIV. Autopsy studies reveal a substantial proportion of TB cases that were undiagnosed ante mortem , underscoring the limitations of current diagnostic approaches. The co-infection of TB with HIV exacerbates disease prog…
Igari H, Takayanagi S, Yahaba M, Tsuyuzaki M, Taniguchi T, et al.
Introduction Human immunodeficiency virus (HIV) infected individuals are at increased risk of developing active tuberculosis (TB). TB incidence remains higher than in non-HIV subjects after antiretroviral therapy (ART) initiation. This study was conducted to estimate the prevalen…