Showing 176–200 of 200 documents
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Chenin Ryan, Angel Moore, Matthew J. Davis, Caitlin Yazel, Shabnam Momtahen, et al.
…ase inhibitors (MEKi) represent a promising new therapy for pediatric patients with low-grade gliomas, which frequently have abnormal signaling within the mitogen-activated protein kinase (MAP kinase) pathway. However, understanding of long-term efficacy and toxicity is limited i…
Kulwinder Kaur
…ate the utility of CBNAAT in enhancing TB case detection in pediatric household contacts of pulmonary positive TB patients. Materials and Methods: It was an observational prospective study including 200 contacts from July 2019 to June 2020 on pediatric household contacts (0- 18 y…
Buonsenso D, Pata D, Visconti E, Cirillo G, Rosella F, et al.
…hest computed tomography (CT) scan to evaluate suspected TB pediatric cases is increasing. We retrospectively reviewed records of patients aged <16 years diagnosed with active TB at the Pediatric Infectious Disease Unit of the Catholic University of the Sacred Heart to describe C…
Luh Indrasuari, Sang Ayu Kompiyang Indriyani
…e, we conducted a study to determine the characteristics of pediatric TB patients in West Nusa Tenggara Province General Hospital during COVID-19 pandemic. This study was a retrospective study using registry data from the Pediatric Respirology Division, Department of Child Health…
Maria Efenesia Baffa, Leila Bianchi, Elisabetta Venturini, Nicola Pimpinelli, Samantha Berti
…atitis (AD) is a common disease affecting nearly 20% of the pediatric population in developed countries. The use of biologic therapies, such as dupilumab, has considerably changed the treatment of AD. However, the effects of biologic drugs on the immune system may raise doubts an…
Farsida Farsida, Ayu Farah Syifa, Azka Zifa Tanama Zifa Tanama
…y aims to determine the factors associated with BCG Scar in pediatric TB patients. A cross-sectional design was conducted at the Pisangan and East Ciputat Community Health Centers in January-September 2020. Data collection using medical records and telephone interviews on 35 samp…
Giordano Sosa Soto, Farzana Hossain, Toufiq Rahman, Md Mahfuzur Rahman, Suchitra Kulkarni, et al.
…h has a high tuberculosis (TB) burden, accounting for 4% of pediatric patients estimated to have TB globally. Obtaining microbiological confirmation of disease in children is challenging; in lieu of this, diagnosis often relies on the presence of symptoms, exposure history, physi…
Ryan Naum, Brittany C. Speed
…tinged sputum. Blood-tinged sputum is a rare finding in the pediatric population. Finding the cause and treatment of the hemoptysis in pediatric patients is largely dependent on the history. In children, the most common causes of hemoptysis are infection and tracheostomy-related …
Sara Nogueira Machado, Sofia Branco, Sónia Silva, Catarina Ferraz, Inês Azevedo
…trospective observational study was conducted at a tertiary pediatric pulmonology center in northern Portugal. Pediatric patients diagnosed with bronchiectasis and followed between July 2020 and September 2023 were included. Results A total of 38 patients were included, of whom 1…
Bendig DW
Sterile pyuria is a common finding in pediatric patients. Literature describing the diagnoses as well as clinical characteristics of children with sterile pyuria is lacking. This review was performed to establish an evidence-based approach to the differential diagnosis by way of …
Soeroyo Machfudz, Farida Juliantina Rachmawaty, Aflifia Birruni Sabila
…it can lead to stunting. Children under five years old with pediatric tuberculosis (TB) are particularly susceptible malnutrition. Specific interventions are needed to prevent stunting in this vulnerable group.Objective: The study aimed to improve the nutritional status of childr…
Sunita Dhaked, Nandini Sharma, K.K. Chopra, Ashwani Khanna
Background: Healthcare seeking by pediatric tuberculosis (TB) patients is complicated because of some factors such as lack of knowledge among family members, diagnostic difficulties, limited resources, and treatment challenges. Aims: The aim of this article is to identify the bar…
Nadeem Akhtar Qureshi
… a characteristic finding in advanced elbow tuberculosis in pediatric populations. Notably, both the present adult case and previously described pediatric case series represent advanced-stage disease (Martini stage IV) with significant joint destruction [3], which may explain the…
Zhou H, Pei Y, Xie Q, Nie W, Liu X, et al.
… samples. Methods A total of 64 participants, comprising 43 pediatric PTB and 21 pediatric pneumonia patients were recruited in the present study. BALF samples were collected from the above participants. Parallel comparisons between mNGS and conventional microbial test (CMT) path…
Sharma S, Shulania A, Achra A, Jeram H, Kansra S, et al.
…eria Growth Indicator Tube (MGIT™) culture for diagnosis of pediatric pulmonary tuberculosis from gastric aspirate (GA) samples and to compare Xpert assay and ZN staining with MGIT rapid liquid culture. Materials and methods GA samples from 210 nonexpectorating children, aged bet…
Alejandro Díaz, Dana Danino, Amy L. Leber, Emily Klamet, Stephanie Stack-Simone, et al.
… patients receiving chemotherapy and transplant recipients. Pediatric epidemiological data for this organism are limited. Methods: We report a descriptive review of C. dubliniensis isolates recovered between January 2018 and June 2019 at a large tertiary-care pediatric institutio…
Min Yu, Qi-Jun Jiang, Yuqing He, Fei Zhao, Tang-Ming Jin, et al.
Clinical manifestations of pediatric pulmonary tuberculosis (PTB) are atypical, making diagnosis challenging. This study aims to analyze the clinical characteristics of PTB to provide constructive suggestions for the diagnosis of PTB. A retrospective analysis was conducted on ped…
Nina T. Castillo-Carandang, Lauren M. Leining, Anna M. Mandalakas, Kristy O. Murray, Jinhua Liao, et al.
…r documents the experiences of rural physicians in managing pediatric tuberculosis (TB) cases before and after disasters in Bohol, Philippines. The participants are from the public and private healthcare systems in municipalities heavily affected and less affected by a 7.2-magnit…
D Crehuet Gramatyka, J Cortés Sáez, J Gómez-Chacón Villalba, Alfredo Marco Macián, Á Mínguez Gómez, et al.
…ergilloma (PA) and review surgery's role in PA treatment in pediatric patients. MATERIAL AND METHODS: A descriptive study of patients diagnosed with PA undergoing surgical resection from 2017 to 2019 was carried out. A review of pediatric studies mentioning "aspergilloma", "surgi…
Ness TE, Meiwes L, Kay A, Mejia R, Lange C, et al.
…length, and purity. This same process was performed with 10 pediatric participants diagnosed with pulmonary TB, and the samples underwent tNGS. The FastDNA spin kit for soil showed the best results on model samples spiked with known quantities of BCG, compared to the other extrac…
Dhaked S, Sharma N, Chopra KK, Khanna A, Kumar R
…ovides the extent of patient and health system delays among pediatric tuberculosis (TB) patients. Objectives The study attempted to understand the treatment seeking pathways of pediatric TB patients under revised national tuberculosis control program (RNTCP). Study design and set…
Vallejo BÁ, Lobo AH, García IC, Pérez TB, Mino-Leon G, et al.
…y. However, new infections continue to be recorded, and the pediatric population remains one of the most vulnerable groups in this region. The main objective of the study was to describe the clinical, epidemiological and psychosocial characteristics of new diagnoses of HIV MTCT i…
Guthrie JL, Delli Pizzi A, Roth D, Kong C, Jorgensen D, et al.
…n. Genotyping and whole-genome sequencing (WGS) can enhance pediatric TB investigations by confirming or refuting transmission events. Methods Mycobacterium tuberculosis isolates from all pediatric patients Results Twenty-three children were Canadian-born, 7 to Canadian-born pare…
Johari M, Sharma R, Bagri DR, Malhotra B
…en this study to evaluate the diagnostic value of CBNAAT in pediatric tuberculosis in comparison to other methods like microscopic detection of acid-fast bacilli and detection of mycobacteria-by-mycobacteria growth indicator tube (MGIT). Material and methods This hospital-based, …
Bineeta Kashyap, Neha Gupta, Pooja Dewan, NP Singh, Ashwani Khanna
…ion test (CBNAAT) has improved microbiological diagnosis in pediatric tuberculosis.
 Objectives: We aimed to study association of CBNAAT grading based on cycle threshold value with conventional microbiological diagnosis.
 Methodology: This prospective study was conducte…