Showing 151–175 of 200 documents
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Lianpeng Wu, Xiyue Cai, Shuya Xu, Xuefeng Lin, Shuangliao Wu, et al.
**OBJECTIVE:** This study aimed to analyze the epidemiological characteristics and trends of notified multidrug-resistant tuberculosis (MDR-TB) in Wenzhou City, China, from 2014 to 2023, with a focus on differences between migrant and local populations among reported TB cases. *…
Anna Vyazovaya, Ms Irina Kostyukova, Ms Daria Terentieva, Ms Alena Gerasimova, Dr Oksana Pasechnik, et al.
Discussion: The case highlights the complexities of treating patients with advanced HIV disease and opportunistic infections, particularly NTM mixtures.Challenges in NTM mixture treatment include uncertainties in selecting multi-drug regimens, treatment duration, patient toleranc…
A Nowińskí, Askar Yedilbayev, Joanna Ladomirska, Andrei Dadu, Tatiana Makarevich, et al.
<b>Aim:</b> The aim of this study was to evaluate the influence of the war in Ukraine on prevalence of tuberculosis (TB) and drug-resistant TB (DR -TB) in Poland. <b>Background:</b> Before 2022 Poland was on the way towards TB pre-elimination stage showing decreasing TB…
Patel MH, Kanodia K, Nigam L, Patel R, Suthar K, et al.
Objectives There are scarce data on the incidence and resistance pattern of rifampicin-resistant Mycobacterium tuberculosis among kidney transplant recipients. Materials and methods This is a retrospective, single- center study of kidney transplantrecipients suspected of M. tuber…
Kerubo G, Ndungu P, Shuaib YA, Amukoye E, Revathi G, et al.
Kenya is a country with a high tuberculosis (TB) burden. However, knowledge on the genetic diversity of Mycobacterium tuberculosis complex (MTBC) strains and their transmission dynamics is sparsely available. Hence, we used whole-genome sequencing (WGS) to depict the genetic dive…
Akhlaaq Wazeer, Amar Riaz, Zahida Qasim, Usman Waheed, Amnah Shaukat, et al.
: The causative agent for TB is Mycobacterium tuberculosis which is member of MTC. Mycobacterium tuberculosis is non-motile, rate of growth is very slow, acid fast and rod in shape (bacilli) belongs to the Mycobacterium genus and differs substantially from other bacteria due to t…
Talent C. Dlamini
Background: The tuberculosis (TB) epidemic remains a major global health problem, noting that the Swaziland government had declared the disease a national emergency. Hence the study was aimed to determine the prevalence of TB in Swaziland and further to ascertain whether the circ…
Raman Swathy Vaman, Madhanraj Kalyanasundaram, T. P. Amina, Manoj Murhekar
Objectives: Kasaragod district reports the highest drug-resistant tuberculosis (DR-TB) case notification rates in Kerala. We conducted a cross-sectional study in Kasaragod to describe the DR-TB cases notified from January 2017 to December 2021 and to identify the factors associat…
Arnab Kumar Samanta, K. Pál, Priyanka Saha, Retina Paul
Background: Febrile illness in pediatric populations often poses a diagnostic challenge due to overlapping clinical features across various etiologies. While respiratory infections are common, urinary tract infections (UTIs) are significant contributors to morbidity, frequently c…
Otchere ID, van Tonder AJ, Asante-Poku A, Sánchez-Busó L, Coscollá M, et al.
Background Bovine tuberculosis (bTB) caused by Mycobacterium bovis is a re-emerging problem in both livestock and humans. The association of some M. bovis strains with hyper-virulence, MDR-TB and disseminated disease makes it imperative to understand the biology of the pathogen. …
Zoltán Örlős, Lilla Lörinczi, Balázs Antus, Imre Barta, Zsuzsanna Miklós, et al.
Background: Due to its increasing prevalence and suboptimal treatment, non-tuberculous mycobacterial (NTM) infection is an emerging problem in patients with cystic fibrosis (CF). Detailed description of regional NTM prevalence and distribution, and identification of predictors of…
Nalini Prava Das, Abinash Panda
Introduction: Multidrug-Resistant Tuberculosis (MDR-TB) is a significant public health problem. The number of MDR-TB cases is very high in India and the management is inadequate due to resource constraints. The assessment of MDR-TB burden has to be reliable for programmatic manag…
Zoltán Örlős, Lilla Lörinczi, Balázs Antus, Imre Barta, Zsuzsanna Miklós, et al.
<bold>Background:</bold> The increasing prevalence of non-tuberculous mycobacterial (NTM) infections is an emerging problem in cystic fibrosis (CF) due to the suboptimal treatment options and high relapse rates. Current studies report prevalence rates of sputum NTM ranging from 3…
Cox H, Salaam-Dreyer Z, Goig GA, Nicol MP, Menardo F, et al.
Background South Africa has a high burden of rifampicin-resistant tuberculosis (including multidrug-resistant [MDR] tuberculosis), with increasing rifampicin-monoresistant (RMR) tuberculosis over time. Resistance acquisition during first-line tuberculosis treatment could be a key…
Muhammad Fadhil, Ramadhan Tosepu, Devi Savitri Effendy
Tuberculosis is an infectious disease caused by the germ Mycobacterium tuberculosis. The group of Mycobacterium bacteria in addition to the Mycobacterium tuberculosis that can cause disorders of the airways is known as MOTT (Mycobacterium Other Than Tuberculosis), which can somet…
V.N. Huseynaliyeva
The retrospective analysis of the medical documents of 523 and 96 active tuberculosis patients in Yasamal-Nasimi districts of Baku and Gobustan during the 2011-2015 years indicates that high risk groups in the cities are people aged 19-24, pensioners, home women, prisoners which …
Abdullah M. Alshahrani, Mutasim E. Ibrahim, Ahmed K. Aldossary, Mushabab Alghamdi, Omar B. Ahmed, et al.
Hospitalized patients are likely to have chronic illnesses and are at an increased risk of mortality due to infection caused by MDR bacteria. We aimed to identify carbapenem-resistant genes carrying Klebsiella pneumoniae (K. pneumoniae) isolates and their risk factors recovered f…
Klotoe BJ, Kurepina N, Zholdibayeva E, Panaiotov S, Kreiswirth BN, et al.
The most widely discussed antibiotic-resistant tuberculosis strains ("W" and "B0/W148", "CAO") belong to L2/Beijing Lineage and are characterized by IS6110 insertion sequences at the NTF locus. We present a high-throughput, microbead-based method, called NTF-RINT for detection of…
Acquah SKE, Asare P, Asare P, Osei-Wusu S, Morgan P, et al.
Objective We conducted a cross-sectional study in the five administrative regions of Northern Ghana to determine the diversity of Mycobacterium tuberculosis complex (MTBC) sub/lineages and their susceptibility to isoniazid (INH) and rifampicin (RIF). Methods Sputum specimens were…
Rafael Laniado-Laborı́n
Globally, tuberculosis is one of the top 10 overall causes of death, the leading cause of death from a single infectious agent, and the principal cause of death among subjects living with human immunodeficiency virus infection. The United Nations and the World Health Organization…
Muhammad Khurram, Rida Khalid, Safia Ehsan, Muqdas Fatima, Azka Hafiza, et al.
Mycobacterium tuberculosis, a gram-positive bacterium that causes tuberculosis (TB) in human is still a serious global health concern, especially in Asia where 22 high burden countries are responsible for 80% of the world's TB cases.There are more than 150 known species of M. tub…
Matthias Merker, Egbe, Nkongho F., Yannick R. Ngangue, Comfort Vuchas, Thomas A. Kohl, et al.
Additional file 2: Table S1. Molecular and phenotypic data of MTBC isolates from 195 RR/MDR-TB patients in Cameroon (2013–2015) including patient characteristics.
Sun H, Ma Z, Ai F, Han B, Li P, et al.
Background In this study, we conducted this population-based study to evaluate the genetic diversity and clustering rate of Mycobacterium tuberculosis (MTB) strains using the whole-genome sequencing (WGS), to better understand its transmission in Ordos. Methods All patients with …
Nyasulu PS, Doumbia CO, Ngah V, Togo ACG, Diarra B, et al.
Purpose of review This review addresses the escalating global challenge of multidrug-resistant tuberculosis (MDR-TB) in Sub-Saharan Africa, with a focus on its complex comorbidity with HIV/AIDS. Emphasizing the urgency of the issue, the review aims to shed light on the unique hea…
María Dolores Ayllón, C Sobrino, Cristina Bilbao, M García-Trevijano, M Escario, et al.
<h3>Background and importance</h3> Inadequate therapeutic regimens and lack of adherence due to adverse effects of antituberculosis drugs have made resistance to these drugs a major public health problem. A better understanding of these issues may lead to better outcomes. <h3>Aim…