Showing 126–150 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Jabar Babatunde Pacome Agbo Achimi Abdul, Micheska Epola Dibamba Ndanga, Jean Ronald Edoa, Rhett Chester Mevyann, Guy Mfoumbi Ibinda, et al.
…d procedures. <h3>Results</h3> Our findings showed that the HIV-TB co-infection rate was 14.1%, and the mean age of the participants was 31.94 years. We observed that 65.2% of patients had MDR-TB, 19.6% had Pre-XDR, 14.1% had RR-TB, and 1.1% had XDR-TB. We identified three main l…
Dimpi, DR DEEPA BISHT
…ti-drug resistant (MDR) strains and the dual infection with HIV & diabetes.A newly identified TB threat which leaves patients virtually untreatable using currently available anti-TB drugs is XDR-TB.Aminoglycosides are commonly used in the tuberculosis treatment and are drug of ch…
Lindiwe Modest Faye, Ntandazo Dlatu, Mojisola Clara Hosu, Wezile Wilson Chitha, Teke Apalata
…worker tracing, digital adherence monitoring, integrated TB-HIV care, and governance dashboard oversight. Machine-learning models were intentionally used as explanatory tools rather than predictive models to assess the internal coherence of the CE-CG framework. The observed perfe…
The Lancet Microbe
…D-19 pandemic had a devastating impact on the fight against HIV, TB and malaria in 2020”. This outlined the first decline in programmatic results in the history of the Global Fund. The scale of this impact on tuberculosis in 2020, was a 19% decrease in the number of people treate…
Junping Liu, Yue Zhou, Juan Guan, Yaping Liu, Weijian Song, et al.
…atterns and temporal trends in the global disease burden of HIV-negative TB among adults aged ≥60 years from 1990 to 2021. **METHODS:** Data on incidence, deaths, and disability-adjusted life-years of TB, drug-susceptible TB, multidrug-resistant TB (MDR-TB), and extensive…
Ignatius EH, Dooley KE
Tuberculosis (TB) has now surpassed HIV as the leading infectious cause of death, and treatment success rates are declining. Multidrug-resistant TB, extensively drug-resistant TB, and even totally drug-resistant TB threaten to further destabilize disease control efforts. The seco…
Ivy Rukasha, Kabelo Gabriel Kaapu, Sarah M Fortune, Molebogeng Ruth Lekalakala-Mokaba
…rowing worry, especially in areas with high rates of TB and HIV. This study aimed to compare BDQ-based regimens to non-BDQ-based treatments over a four-year period (2016-2019) to retrospectively examine the treatment outcomes of DR-TB patients in Limpopo Province, South Africa. …
Swinkels HM, Jilani TN, Tobin EH
…h Organization (WHO) declared TB a global emergency when an HIV-driven increase in incidence reversed decades of progress toward global TB control. In 2015, the WHO set an ambitious goal to reduce TB incidence by 90% by 2035.[WHO. End TB 2022.] However, the world is unlikely to r…
L. Parolina, Olga Otpuschennykova, Natalia Kazimirova, N. P. Doktorovа
…ients with XDR and 122 drug sensitive (DS) TB patients (non HIV infected) was conducted in 2015-2018. Bivariate and multivariable logistic regression analysis was used to identify the determinants associated with XDR-TB. <b>Results:</b> Social TB-risk factors were identified in 9…
N. A. Sosova, T. A. Zadremaylova, Н. М. Коновалова, A. V. Abramchenko, M. I. Romanova, et al.
…resistant tuberculosis (MDR, pre-XDR, XDR) depending on the HIV status of patients in Stavropol Region from 2019 to 2022. Subjects and Methods . In a retrospective study, chemotherapy outcomes for pulmonary tuberculosis (TB) were evaluated with distribution by treatment regimens …
Chirag J Gohil, Ketan C. Parmar, Priyanka R. Patel, Jignakumari J. Gohil
…ance (XDR) were seen. The diagnosis of drug-resistant TB in HIV-positive persons is more difficult and may be confused with other pulmonary or systemic infections. Management of patients with mono- or poly-resistant TB will be done with standard first line chemotherapy. Treatment…
Elena Khimova, Grigory Volchenkov, Д. В. Перхин, Elena S. Dyzhik, O. M. Sveshnikova, et al.
…z). The molecular genetic verification of MDR-TB was 98.2%. HIV and hepatitis C co-infection was confirmed for 13.2% and 16.8% of participants, respectively. Adults, two teenagers and a pregnant woman participated in the study. Results. Favorable treatment outcomes were registere…
О. М. Raznatovska, V.I. Petrenko, О.S. Shalmin, R.M. Yasinskyi, A.V. Fedorec, et al.
…ndicates its late diagnosis. The patient was not tested for HIV infection when tuberculosis was detected in the primary care, and after 2.5 months it was firstly found and accompanied by severe immunosuppression (CD4 lymphocytes count was 94 cells). This fact also indicates a la…
Osman M, Harausz EP, Garcia-Prats AJ, Schaaf HS, Moore BK, et al.
… 11 years, 32 (87%) had pulmonary TB, and 29 had a recorded HIV status; 7 (24%) were infected with HIV. Median treatment duration was 7.0 months for the intensive phase and 12.2 months for the continuation phase. Thirty (81%) children had favorable treatment outcomes. Four (11%) …
Xinen Kong, Jiayi Yang, Jiajun Wang, Jiaxiang Li, Xiaoying Jin, et al.
…xtensively drug-resistant TB, human immunodeficiency virus (HIV) co-infection, lack of effective vaccines and diagnosis methods, as well as the low treatment efficacy of anti-TB therapeutics lead to multiple difficulties and challenges in TB control. Host immune defense is critic…
Ivan Banjuradja, Asep Purnama
… drug resistant (Pre-XDR TB), Human Immunodeficiency Virus (HIV) co-infection, emergence of serious acute psychosis side effect, and the drop out management. Discussion: We will discuss the management of each individual’s problem that arises during the antitubercular treatment mo…
Kumar G, Adhikrao PA
…orldwide. The co-infection of human immunodeficiency virus (HIV) in association with TB burdens the healthcare system substantially. Notably, M.tb possesses defence against most antitubercular antibiotic drugs, and the efficacy of existing frontline anti-TB drugs is waning. Also,…
O. V. Filinyuk, A. S. Аlliluev, D. E. Аmichba, П. Н. Голубчиков, Yu. S. Popelo, et al.
…T) in new tuberculosis patients with the reference to their HIV status and to assess their treatment outcomes. Subjects and methods. The presented results were obtained from a retrospective cohort study of 788 new tuberculosis patients who were registered for MDR TB treatment at …
Malík I, Čižmárik J, Pecháčová M
…r as the active component of complex treatment regimens) of HIV-1 negative as well as HIV-1 positive patients suffering from MDR-TB or XDR-TB. Mechanism of anti-TB action of perchlozone might be similar to that of thiacetazone, which belongs into the same chemical class. Perchloz…
Preeti Sharma, Jinendra Singh Chauhan, Birjesh Singh
…y drugresistant (DR) TB and comorbidities with diabetes and HIV. Exiguous dosing, incomplete treatment course, and the ability of the tuberculosis bacilli to tolerate and survive current first-line and second-line anti-TB drugs, in either their latent state or active state, has r…
Nadim Chhipa, Pinkal Patel, Neil Panchal, Rakesh Parmar
…interactions of the current TB drugs with the ARVs taken by HIV positive people, with increased number of multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains, and the ineffectiveness of the current treatment against latent TB are challenges to be overcome…
Yesypenko S, Grigoryan R, Sereda Y, Denisuk O, Kovtunovich L, et al.
Introduction Odesa province has the highest TB/HIV prevalence in Ukraine, exceeding the total prevalence in the country by 3 times. The objective of this study was to investigate the unfavorable treatment outcomes and associated factors in patient with drug-resistant (DR) TB in p…
José-María García-García, Mercedes Sanz, José Antonio Gullón Blanco, Xavier Clop i García, Joan Pau Millet Vilanova, et al.
…e was 37.9±17.9 years, 66 men (71%), foreigners 61 (65.6%), HIV+ 6 (6.5%), with previous TB treatment 23 (24.7%). They came from most of the Spanish Autonomous Communities. They had RR-TB (10), MDR-TB (74), XDR-TB (8). Thirty-seven patients (39.8%) received bedaquiline, 77 (82.8%…
Jacqui Wise
…31 (58,5%) patients, contact with MDR/XDR TB in 27 (50,9%), HIV infection in 22 (41,5%), low treatment compliance in 27 (50,95%) and 14 (26,4%) patients interrupted courses, including BDQ, LNZ, Mfx. <b>Measurements and Main Results:</b> TB duration up to three years or more, сont…
Elena Kildusheva, Igor Medvinsiy, Sergey Skornyakov, Tayiana Lugovkina, Tatiana Umpeleva, et al.
…31 (58,5%) patients, contact with MDR/XDR TB in 27 (50,9%), HIV infection in 22 (41,5%), low treatment compliance in 27 (50,95%) and 14 (26,4%) patients interrupted courses, including BDQ, LNZ, Mfx. <b>Measurements and Main Results:</b> TB duration up to three years or more, сont…