Showing 51–75 of 200 documents
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Kaushik G, Vashishtha R, Tripathi H, Yadav RN
…onal, as well as longitudinal in nature, which includes 223 HIV-positive patients, 150 HIV-positive patients with latent tuberculosis (TB) infection, 150 HIV-positive patients with active TB, 200 HIV-negative newly diagnosed sputum smear positive pulmonary TB patients, and 205 he…
Tan Y, Guo W, Zhu Q, Song S, Xiang Y, et al.
…ells in the natural course of human immunodeficiency virus (HIV) and tuberculosis (TB) co-infection haven't been fully elucidated. Methods The function of peripheral proinflammatory, regulatory and cytotoxic cytokine-secreting cells were investigated by direct intracellular cytok…
Clare Bristow, Uli Schwab
Introduction Patients with Human Immunodeficiency Virus (HIV) are at an increased risk of latent Tuberculosis (TB) reactivation. HIV TB concurrent infection increases mortality and reduces patient quality of life. Screening for latent TB allows treatment to commence, preventing r…
van Woudenbergh E, Irvine EB, Davies L, de Kock M, Hanekom WA, et al.
…the largest cause of death in human immunodeficiency virus (HIV)-infected individuals in part due to HIV-related CD4 + T cell loss, rendering patients immunocompromised and susceptible to a loss of Mycobacterium tuberculosis control. However, in light of increasing data pointing …
Meher Sasmita, Meher Bhanjan, Rathore Rajkumari, P. G Dhone, Rai Neeta
HIV is the most important cause of death amoung tuberculosis patient. About 25 % of all causes of death. HIV promote progression of latent TB infection, which become difficult to diagnose initially later on comorbidity and mortality leads to late diagnosis and death of patients. …
Bamidele David Ajayi, John Omotola Ogunkoya, Folake Olubunmi Ajayi
…s: It was aimed to assess the prevalence of latent TB among HIV+ patients, evaluate the coverage of isoniazid preventive therapy (IPT), the continuous risk of latent tuberculosis infection, and factors associated with the presence of latent Tb in HIV+ patients.
 Methods: Thi…
Susan Dorman, MD, Mark Nicol, MBChB, PhD, Mischka Moodley, MBChB, DTM&H, FCPath(Micro)SA
…el lateral-flow urine LAM test in detecting tuberculosis in HIV-infected adults. A secondary study objective is to evaluate the accuracy and diagnostic yield of the Cepheid Xpert MTB/Rif test in detecting tuberculosis in the blood of HIV-infected adults. Background: Tuberculosi…
Niken Ayu Farida Salim, Zulfian, Neno Fitriyani Hasbie, Arif Effendi
The interaction between TB and HIV infection is complex. In HIV-infected individuals, this situation will decrease the immune system and increase vulnerability to TB incidence. HIV causes reactivation, reinfection, and progression of latent TB infection to active tuberculosis. It…
Yuniati SK, Kusmiati T
…use of death in patients with human immunodeficiency virus (HIV)/AIDS. About 60% of HIV-positive individuals with latent TB infection (LTBI) develop active TB. Isoniazid preventive therapy (IPT) is recommended by the World Health Organization to prevent the progression of active …
M. S. Grabovskaya, Л. Н. Мотанова, D.А. Kudlаy, Н. П. Докторова
We analyzed the epidemic situation of TB/HIV co-infection in Primorsky Krai in 2008–2023 and revealed the tendency towards escalation of TB/HIV co-infection, which required a detailed analysis and improved effectiveness of preventive measures against TB infection in HIV-positive …
Ngari MM, Rashid MA, Sanga D, Mathenge H, Agoro O, et al.
…kground Although tuberculosis (TB) patients coinfected with HIV are at risk of poor treatment outcomes, there is paucity of data on changing trends of TB/HIV co-infection and their treatment outcomes. This study aims to estimate the burden of TB/HIV co-infection over time, descri…
Tomoki Nishiguchi, Godwin Mtetwa, Alexander Kay, Gugu Maphalala, Emily M. Mace, et al.
…ol disease. The risk of disease progression is higher among HIV-infected individuals and children, therefore we evaluate how HIV and age alter the balance of cytotoxic versus immune regulatory NKT immune phenotype in individuals with TB and latent Mycobacterium tuberculosis infec…
Agudelo CA, Álvarez MF, Hidrón A, Villa JP, Echeverri-Toro LM, et al.
… the most common causes of hospitalisation in patients with HIV. Despite this, hospital outcomes of patients with this co-infection have rarely been described since antiretroviral therapy became widely available. Methods Prospective cohort study of HIV-infected adult patients hos…
Sr Mary Nyambura Mwangi, Virginia M. Kitetu, Isaac O. Okwany
A non-linear HIV-TB co-infection has been formulated and analyzed. The positivity and invariant region has been established. The disease free equilibrium and its stability has been determined. The local stability was determined and found to be stable under given conditions. The b…
Jorge Gonzalez Mendoza
Since the early days of HIV infection, back in the eighties, TB – particularly extrapulmonary TB emerged as one of the opportunistic infections affecting these patients, specifically as a reactivation of latent TB infections. A diagnosis of TB in the context of HIV infection was …
Susan Dorman, MD, Yukari Manabe, MD
…e lipoarabinomannan (LAM) test in detecting tuberculosis in HIV-infected adults. A secondary study objective is to determine the accuracy, efficiency, costs, and cost-effectiveness of various combinations of Tuberculosis (TB) diagnostic tests, including the novel Xpert MTB/Rif t…
Saraceni V, Benzaken AS, Pereira GFM, Andrade KB, Oliveira PB, et al.
…n reported AIDS cases, to compare the characteristics of TB/HIV subjects with those without TB and to evaluate survival with or without TB in Brazil. Methods The data source was the linked database between AIDS (2011-2014) and TB (2011-2014) databases from the Notifiable Diseases…
DeAtley T, Hamada Y, Baddeley A, Werner P, Kanchar A, et al.
…mmends TB preventive treatment (TPT) for people living with HIV, including pregnant women. Uptake of this policy recommendation in this subpopulation and country alignment with WHO guidance is unclear. METHODS: We conducted a policy review in 38 WHO high TB and TB-HIV burden coun…
Adams S, Ehrlich R, Baatjies R, Dendukuri N, Wang Z, et al.
…th Africa, a tuberculosis and human immunodeficiency virus (HIV) endemic setting Methods: 505 HCWs were screened for LTBI using TST, QuantiFERON-gold-in-tube (QFT-GIT) and T-SPOT.TB. A latent class model utilizing prior information on test characteristics was used to estimate tes…
Mareli Claassens, Chawangwa Modongo, Tadesse Kassaye, Gunar Guenther, Emmanuel Nepolo, et al.
…an context. A particular gap in knowledge was the effect of HIV and tuberculosis (TB) on the outcomes of Covid-19 disease. We implemented a research study that addressed critical questions concerning Covid-19 disease epidemiology in the context of low resource countries with high…
Elsa Anes, Wondwossen Amogne
…eath among people living with human immunodeficiency virus (HIV) (PLWH) [1], and was responsible for approximately twice as many deaths as HIV/ acquired immunodeficiency syndrome (AIDS) alone [2]. The immune responses to monoinfection with the causative agent, Mycobacterium tuber…
Kaushik G, Vashishtha R
…iation of innate immune responses, therefore, the effect of HIV infection on TLRs gene expression was investigated in functional context through mRNA levels estimations of selected TLRs. Methods In the present study mRNA gene expression of TLR2, TLR4 and TLR9 has been investigate…
Wadee R, Wadee AA
…e of the components of the immune response in granulomas in HIV-positive and -negative lymph nodes. We investigated the immunohistochemical profiles of CD4+, CD8+, CD68+, Th-17, Forkhead box P3 (FOXP3) cells, accessory molecule expression (human leukocyte antigen [HLA] classes I …
Kaushal D, Singh DK, Singh DK, Mehra S
HIV and TB are the cause of significant worldwide mortality and pose a grave danger to the global public health. TB is the leading cause of death in HIV-infected persons, with one in four deaths attributable to TB. While the majority of healthy individuals infected with M. tuberc…
Adeline M Nyamathi, PhD
… TBI treatment adherence, HBV vaccination, and adherence to HIV therapy. This study will assess the impact of the TBI program that the investigators have developed, as a single arm intervention study, among 76 eligible TBI homeless adults on completion of 3HP treatment, decrease…