Showing 26–50 of 200 documents
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Enane LA, Christenson JC
…-resistant infections. Global burdens of drug-resistant TB, HIV and gram-negative pathogens have a particular impact on paediatric age groups, necessitating a paediatric-focused agenda to address emerging resistance. Dedicated approaches are needed to find, successfully treat and…
Dmytro Butov, MD
…n 44% and 32.9% of TB isolates. The first Ukrainian case of HIV was reported in 1987. Today, Ukraine has the highest HIV rate in the Eastern Europe, with increasing proportion of dual infection. For example, in 2002 the prevalence of TB and HIV co-infection was 6.3%, but in 2006 …
Grant Theron, PhD
…hese clinics are representative of many areas where TB (and HIV) are found at high prevalence. If the constraints of working in such areas can be understood and appropriate changes that work made, the investigators believe the outputs and policy changes generated in this study wi…
Sultana ZZ, Hoque FU, Beyene J, Akhlak-Ul-Islam M, Khan MHR, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) in HIV infected individuals is a serious threat to global efforts to combat tuberculosis. Inconsistent findings on the association between HIV infection and MDR-TB were present in many studies. We aimed to review existing data …
Malabad JCM, Ang CF, Palabrica FAR, Cajucom MAM, Gloriani NG, et al.
…e infectious disease, particularly among people living with HIV (PLHIV). Molecular epidemiology provides information on prevalent genotypes of Mycobacterium tuberculosis and disease transmission dynamics, which aid in TB control. Identification of mutations that confer drug resis…
World Health Organization. Regional Office for Europe
…oordinating meeting of the WHO collaborating centres on TB, HIV, viral hepatitis and STI was held in Copenhagen, Denmark, on 11–12 November 2019, and included presentations and discussions. The overall objectives were to review the current activities of the participating WHO coll…
World Health Organization. Regional Office for Europe
… WHO Technical Officers together in order to strengthen TB, HIV and viral hepatitis laboratory diagnostics, testing and monitoring capacity. The most recent developments in these fields were covered during expert presentations followed by extensive discussions. Panel discussions,…
Sydney Rosen
…o present at the study clinic for TB screening and optional HIV testing, providing a reward to the index patients for participating, and entering index patients whose contacts do present into a lottery to win a prize.The effectiveness of the intervention in screening a high propo…
H Nyilana, K Reis, B Seepamore, R Perumal, A Wolf, et al.
… adherence support interventions for people with MDR-TB and HIV. Addressing these factors through tailored interventions is crucial to improving care engagement and challenging one-size-fits-all approaches to TB prevention.
Singh R, Fatima N, Shukla I, Shameem M
…on opportunistic infection in human immunodeficiency virus (HIV)-infected individuals. The risk of eventually developing active TB from latent TB infection (LTBI) is about 10% per year in HIV-positive patients in contrast to 10% lifetime risk in HIV-negative patients. Until recen…
Song Y, Jin Q, Qiu J, Ye D
…e emergence of multidrug-resistant tuberculosis (MDR-TB) in HIV-positive people poses a significant challenge to international efforts to eradicate tuberculosis (TB). Many studies found conflicting results when examining the correlation between HIV and MDR-TB. The purpose of the …
Rubinstein M, Makhon A, Losev Y, Valenci GZ, Gatt YE, et al.
Coinfection of HIV and multidrug-resistant tuberculosis (MDR-TB) presents significant challenges in terms of the treatment and prognosis of tuberculosis, leading to complexities in managing the disease and impacting the overall outcome for TB patients. This study presents a remar…
Zhou M, Liu S, Li Q, Wang Q, Zhu M, et al.
… of TB isolates from tuberculosis patients with and without HIV (TB-HIV patients and TBw/oHIV patients) in Chengdu, Sichuan, China. Methods Isolates from respiratory samples of TBw/oHIV patients and TB-HIV patients hospitalized between January 2014 and December 2017 were collecte…
Mukonzo J, Aklillu E, Marconi V, Schinazi RF
HIV-positive TB co-infected patients are at increased risk of multidrug-resistant (MDR)-TB compared to HIV-negative patients. Co-treatment of MDR-TB and HIV is common particularly in Sub-Saharan Africa where the co-morbidity is endemic. We discuss potential cellular metabolic pat…
Bitrus Joshua Barde, Joseph Okopi, Isiyaku Ahmadu
… the global fight for the elimination of Tuberculosis (TB), HIV coinfection with MDR-TB makes TB management even worse. Previous studies have reported poorer outcomes and staggering high mortality rates among persons coinfected with HIV and MDR-TB. This coinfection is said to be …
Marsha Zahrani, Rebekah Juniati Setiabudi, Helmia Hasan, Manik Retno Wahyunitisari
…n transmission and TB treatment failure. In addition to TB, HIV and diabetes mellitus may raise the risk of TB MDR. To determine the TB MDR risk factors, it's critical to understand the prevalence of TB MDR patients with TB, HIV, and diabetes mellitus histories.Methods: This stud…
Song Y, Jin Q, Qiu J, Ye D
…e emergence of multidrug-resistant tuberculosis (MDR-TB) in HIV-positive people poses a significant challenge to international efforts to eradicate tuberculosis (TB). Many studies found conflicting results when examining the correlation between HIV and MDR-TB. The purpose of the …
Spooner E, Reddy S, Ntoyanto S, Sakadavan Y, Reddy T, et al.
BACKGROUND: TB diagnosis in patients with HIV is challenging due to the lower sensitivities across tests. Molecular tests are preferred and the Xpert ® MTB/RIF assay has limitations in lower-income settings. We evaluated the performance of loop-mediated isothermal amplification (…
Hong H, Budhathoki C, Farley JE
…test in tuberculosis (TB) and human immunodeficiency virus (HIV) endemic countries in sub-Saharan Africa. However, whether HIV coinfection is associated with a higher incidence of AG-induced hearing loss during MDR-TB treatment is controversial. Objective To evaluate the impact o…
Miriam Abadie, Alexander Kay
…ug-resistant tuberculosis (DR-TB) treatment for people with HIV (PWH), including drug-drug interactions, investigational medications and host-directed therapy, as well as emerging evidence on novel treatment regimens, post-TB complications, and DR-TB medication resistance among P…
Hassan-Moosa R, Motsomi KW, Narasimmulu R, Sivro A, Naidu KK, et al.
…tcomes of three patients with human immunodeficiency virus (HIV), DR-TB and COVID-19. Case one A virologically suppressed 31-year-old man on antiretroviral therapy (ART) and multidrug-resistant (MDR)-TB treatment presented with mild COVID-19 and was hospitalised for 10 days of cl…
Bhim Bahadur Subba, N. Rimal, Bikash Shrestha
…TB is considered one of the opportunistic infection among PLHIV. The increasing burden of HIV/TB co-infection among key population cause problem to maintain adherence to ART and DOTS services. The emergence of MDR-TB is one of the greatest challenge to control and management of b…
Fred Monje, Daniel Kadobera, Yakubu Owolabi, Lilian Bulage, Alex Riolexus Ario, et al.
…rs associated with completion of TB treatment at MRRH among HIV-positive and HIV-negative patients. Results: We identified 331 TB case notifications among children <15 years. TB case notification rates declined from 6.6/100,000 in 2013 to 2.2/100,000 in 2017 [odds ratio (OR)=0…
Pinaka Swasti Ratu Suryantari, I Irnawati
… in patients with Multy-Drug Resistant (MDR) TB and TB with HIV. To find out the description of medication adherence in pulmonary TB patients and and characteristics in pulmonary TB patients. This study used a literature review design. The pill count compliance measurement method…
Monica R A Pachar Flores, Ricardo Gollini, Anabelle Drake, María Alejandra Rengifo, Gissel A Figueroa, et al.
…r patients are at higher risk due to immunosuppression from HIV, chemotherapy, and corticosteroids. Despite 155,917 consultations and 50,306 radiotherapy treatments at ION in 2022, TB prevalence in oncology patients is understudied. This study examines TB’s clinical and epidemiol…