Showing 26–50 of 87 documents
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Kassaw A, Kefale D, Aytenew TM, Azmeraw M, Agimas MC, et al.
…national pooled proportion and incidence of mortality among TB-HIV co-infected patients were considered to be still high. The authors strongly recommended scale up and continuous provision of cotrimoxazole and isoniazid preventive therapy. In addition, early identification and tr…
Vonasek BJ, Rabie H, Hesseling AC, Garcia-Prats AJ
…ally. However, advances in children have lagged behind, and TB-HIV coinfection continues to be a major driver of pediatric mortality in many settings. This review highlights recent research findings in the areas of prevention, diagnosis, and treatment of HIV-associated childhood …
Asiko Ongaya, Megan Files, Yazmin B. Martinez-Martinez, Robi Chacha, Jeremiah Kyalo, et al.
…public health concern. Complexities associated with Mtb/HIV coinfections, including in those virally suppressed with anti-retroviral therapy (ART), present significant challenges to efforts to reduce both infections. The pattern of cytokines produced by T helper (Th) lymphocytes …
Nardotto GHB, Bollela VR, Rocha A, Della Pasqua O, Lanchote VL
…iving with HIV. This study aims to assess the effect of HIV coinfection and antiviral therapy on the plasma exposure to FLATDs in patients with TB. HIV negative (TB-HIV- group; n = 15) and HIV positive (TB-HIV+ group; n = 18) adult patients with TB were enrolled during the second…
Tapati Mondal, Abhik Sarkar, Surya Jyati Chaudhuri, Julius Rahaman
…o act synergistically and result in higher mortality rates. TB-HIV coinfection and emergence of drug resistant forms of MTB can impact positively on treatment outcomes. Aims and Objectives: The aim of this study was to determine of the prevalence of TB-HIV co-infection among MTB …
Widiyanti M, Adiningsih S, Kridaningsih TN, Fitrianingtyas R
…uses mortality among People Living with HIV (PLHIV), so the treatment of TB-HIV coinfection is crucial. The study aimed to identify the determinants contributing to TB coinfection among PLHIV in Papua. It is a descriptive-analytic study with a cross-sectional design involving 188…
Tamene W, Abebe M, Wassie L, Mollalign H, Bauer K, et al.
… microbial products have not been well studied. Method HIV (TB-HIV+), TB (TB+HIV-) and TB/HIV co-infected (TB+HIV+) patients as well as apparently healthy controls (TB-HIV-) were recruited. TB and HIV patients were treatment naïve while TB/HIV patients were both ART naïve and exp…
Ahmed A, Weldegebreal F, Tebeje F, Dessie Y
Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection pose significant challenges to global health, particularly in achieving the target of ending TB. However, the impact of HIV status on TB treatment outcomes remains unclear, especially in eastern Ethiopia. This s…
Uzochukwu Godswill Ekeleme, Ikenna Oluebube Ogini, Stanley Chinedu Eneh, Ugonma Winnie Dozie, Stephanie Adiruo Akunna, et al.
…miciled in Sub-Saharan Africa. Given the paucity of data on TB-HIV co-infection in children, this study aimed to understand the factors associated with co-infection in children receiving antiretroviral therapy (ART) in Imo State, Nigeria. We used a matched case-control study desi…
Enimil A, Antwi S, Yang H, Dompreh A, Alghamdi WA, et al.
…er than 3 years old (young children) with tuberculosis (TB) coinfection. To date, there are insufficient data to recommend nevirapine-based therapy during first-line antituberculosis (anti-TB) therapy in young children. We compared nevirapine pharmacokinetics (PK) in HIV-infected…
Thuli Mthiyane
Introduction: Biomarkers of tuberculosis (TB) diagnosis and treatment response in patients coinfected with human immunodeficiency virus (HIV) are a necessity to ensure early diagnosis and adequate monitoring of TB treatment response. We conducted 3 sub-studies: study 1 was a bioa…
Caian L. Vinhaes, Betania Nogueira, Cristina da Silva Almeida Damasceno, Emanuelle Souza Oliveira Ferreira, Euclimeire da Silva Neves, et al.
…eading cause of death among people living with HIV (PLHIV). TB-HIV coinfection contributes substantially to global TB mortality. While previous studies have linked early mortality to delayed initiation of antiretroviral therapy (ART) and disseminated TB, the immunological mechani…
Josimara Brunyelly Ximenes de Sousa
…of liberty (PDL). In Rio Grande do Sul, the high incidence, TB-HIV coinfection, and prison conditions such as overcrowding and poor sanitation favor transmission and hinder disease control. The objective was to analyze the epidemiological profile of tuberculosis in men deprived o…
Gemechu LL, Debusho LK
…a; there is, however, no information on spatial patterns of TB-HIV coinfection in the country at the districts level at least using yearly data. This paper, therefore, aimed at determining the spatial clustering of TB-HIV coinfection prevalence rates in the country at the distric…
Josimara Brunyelly Ximenes de Sousa
…of liberty (PDL). In Rio Grande do Sul, the high incidence, TB-HIV coinfection, and prison conditions such as overcrowding and poor sanitation favor transmission and hinder disease control. The objective was to analyze the epidemiological profile of tuberculosis in men deprived o…
Madan C, Chopra KK, Satyanarayana S, Surie D, Chadha V, et al.
…man immunodeficiency virus (HIV) co-infection have worse TB treatment outcomes compared to patients with TB alone. The distribution of unfavourable treatment outcomes differs by socio-demographic and clinical characteristics, allowing for early identification of patients at risk.…
Amirkhani A, Humayun M, Ye W, Worku Y, Yang Z
…identified prison TB research as a top priority to guide TB treatment/control interventions. Methods We retrospectively analyzed 921 notified TB cases that were diagnosed at Kality Federal Prison, Ethiopia during 2009-2017. To assess trends of microbiologically confirmed pulmonar…
Asmah Amirkhani, Maheen Humayun, Wen Ye, Yoseph Worku, Zhenhua Yang
…identified prison TB research as a top priority to guide TB treatment/control interventions. Methods: We retrospectively analyzed 921 notified TB cases that were diagnosed at Kality Federal Prison, Ethiopia during 2009-2017. To assess trends of microbiologically confirmed pulmona…
Byamungu LN, du Preez K, Walters E, Nachega JB, Schaaf HS
…diagnoses in children. Design Retrospective cohort study in TB-HIV co-infected children aged Results Of 88 children with TB-HIV co-infection, 37 (42%) had a simultaneous TB-HIV diagnosis; 51 children had been known to have HIV before their TB diagnosis. Interruption of antiretrov…
Gbeasor-Komlanvi FA, Sadio AJ, Adama OI, Zida-Compaore WIC, Tchankoni MK, et al.
BACKGROUND: Good adherence is essential in the treatment of TB. The aim of this study was to describe medication consumption patterns and to assess factors associated with adherence to TB treatment among TB patients in Lomé, Togo. METHODS: A cross-sectional study was conducted am…
Ufoaroh CU, Anyabolu EN, Okoye IC, Chinweuba IS
…global healthcare problem. In Sub-Saharan African countries TB-HIV co-infection is an evil duo. This study sought to evaluate TB characterization and mortality rate in TB subjects in a semi-urban tuberculosis center in Southeast Nigeria. Methodology This was a retrospective study…
Amelo Bolka, Selamawit Sikuare, Assefa Philipos Kare, Fentaw Wassie Feleke, Tafese Bosha
…ry diversity (APR = 1.56; 95% CI: 1.21-2.01), TB-HIV coinfection (APR = 1.65; 95% CI: 1.23-2.21), and parasite infection (APR = 1.78; 95% CI: 1.41-2.25). The identified predictors of anemia among PWTB were food insecurity (APR =&#x…
Gabriela Tavares Magnabosco, Fernanda de Paulo Pedroso, Isadora Gabriella Silva Palmieri, Letícia Baio de Souza, Heitor Hortensi Sesnik, et al.
In Brazil, tuberculosis-human immunodeficiency virus (TB-HIV) coinfection remains a major public health challenge despite advances in antiretroviral therapy and tuberculosis preventive treatment (TPT) Civil society has historically contributed to HIV responses, but little is know…
Nabisere R, Musaazi J, Denti P, Aber F, Lamorde M, et al.
…py, although very effective, has limitations including long-treatment duration with a possibility of non-adherence, drug interactions, and toxicities. Dose escalation of rifampicin, an important drug within the regimen, has been proposed as a potential route to higher treatment e…
Yang H, Antwi S, Maranchick N, Dompreh A, Amissah AK, et al.
… to address these questions. DESIGN/METHODS: Children on TB treatment were enrolled. After 4 weeks on therapy, blood samples were collected at pre-dose, 1, 2, 4, 8, and 12 h post-dose for pharmacokinetic analysis. Plasma drug exposure below and above the lower and upper bounds of…