Showing 1–25 of 119 documents
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Osei Bonsu E, Addo IY, Adjei BN, Alhassan MM, Nakua EK
Objective To assess the prevalence, treatment outcomes and determinants of tuberculosis (TB)-HIV coinfection in Ghana. Study design A retrospective review of TB case register for Kwabre East Municipality was conducted for the period 2010-2020 to identify TB-HIV coinfections. Sett…
Solange Mudih Ngala, Disline Manli Tantoh, Oswald Ndi Nfor, Gamo Djouomo Francis, Adeline Fitame, et al.
…ng impacts across age cohorts. Evaluating tuberculosis (TB) treatment outcomes, especially among HIV patients across different age groups, is crucial for effective TB management. This study assessed the age-specific relationship between HIV status and TB treatment outcomes among …
Tola A, Mishore KM, Ayele Y, Mekuria AN, Legese N
…major global health challenges in the twenty-first century. TB-HIV co-infected people are facing multifaceted problems like high lost to follow up rates, poor treatment adherence, high TB recurrence rate, and high mortality risk. Our objective was to assess the outcomes of TB tre…
Yuyun Monita, Putroue Keumala Intan
…dual is affected by TB and HIV/AIDS in his body is called a TB-HIV/AIDS coinfection. This research aims to minimize the populations of TB-HIV/AIDS coinfection with a minimum expenditure on medical expenses, that means minimizing the objective’s function ( ) or purpose function. I…
Maemun S, Mariana N, Rusli A, Mahkota R, Purnama TB
…ART) is essential to increase the survival of patients with TB-HIV coinfection. The aim of this study is to investigate the effect of ARV treatment initiation within TB treatment duration for the survival of patients with TB-HIV coinfection. Methods This is a retrospective cohort…
Zelnick JR, Seepamore B, Daftary A, Amico KR, Bhengu X, et al.
…cial workers may have a unique role to play in improving DR-TB-HIV outcomes. We designed, implemented and evaluated a model-based pilot training course on patient-centered care, treatment literacy in DR-TB and HIV coinfection, patient support group facilitation, and self-care. Te…
Sukesha Gamit, Mohamed Anas Mohamed Faruk Patni, Hiteshree Patel, Chintan Gamit, Jayendrakumar Kosambiya
**BACKGROUND:** Human immunodeficiency virus-tuberculosis coinfection represents a major public health problem, especially in resource-poor countries like India. This mixed-method study explores the epidemiological and clinical characteristics, including treatment outcomes of HIV…
Naidoo K, Rampersad S, Karim SA
…key risk factor for the development of active TB infection. Treatment integration is a key in reducing mortality in patients with HIV-TB co-infection. However, this opportunity to improve outcomes of both infections is often missed or poorly implemented. Challenges in TB-HIV trea…
Moges S, Lajore BA
…is a major public health problem in Ethiopia. Patients with TB-HIV co-infection have significantly higher mortality rates compared to those with TB or HIV mono-infection. This systematic review and meta-analysis aim to summarize the evidence on mortality and associated factors am…
Hayibor KM, Bandoh DA, Asante-Poku A, Kenu E
…th challenge in Ghana as well as many developing countries. Treatment outcome monitoring is a vital part of the surveillance needed to successfully eliminate TB. The impact of HIV status and demographic and treatment-related factors on adverse TB treatment outcome has not been st…
Machrumnizar Machrumnizar, Tris Eryando, Adang Bachtiar, Rina Kurniasri Kusumaratna, Meiyanti Meiyanti, et al.
…ify the determinants and epidemiological characteristics of TB-HIV co-infection using data from the 2023 national TB registry. **METHODS:** The study procedures were carried out using a cross-sectional design, analysing univariate, bivariate and multivariate associations between…
Maji D, Agarwal U, Kumar L, V V, Sharma A
…was to evaluate the clinical presentation and outcome of TB treatment in HIV-TB co-infected patients receiving daily anti-tubercular therapy (ATT) and concurrent antiretroviral therapy (ART) at a tertiary respiratory care centre in New Delhi, India. The research was cross-section…
Selimin DS, Ismail A, Ahmad N, Ismail R, Mohd Azman NF, et al.
…tudy aimed to identify the characteristics, unsuccessful TB treatment rate, and determinants of unsuccessful TB treatment outcome among patients with TB-HIV coinfection in Kuala Lumpur. Methods This was a cross-sectional study. The data of all patients with TB-HIV in the federal …
Musaazi J, Sekaggya-Wiltshire C, Kiragga AN, Kalule I, Reynolds SJ, et al.
OBJECTIVE To examine tuberculosis (TB) treatment outcomes from a long-term TB-HIV (human immunodeficiency virus) integrated model of care at the Infectious Diseases Institute Clinic, Kampala, Uganda. METHODS We included HIV-positive adults who were new TB cases initiated on anti-…
Akanbi K, Ajayi I, Fayemiwo S, Gidado S, Oladimeji A, et al.
…g countries. World Health Organization (WHO) recommends 85% treatment success rate for all TB cases as an indicator of TB control. The study aimed at determining TB treatment success rate among TB-HIV co-infected patients and identifying predictors of successful treatment among p…
Md Abdul Kuddus, Sazia Khatun Tithi, Anip Kumar Paul, Thitiya Theparod
… This dual burden exacerbates disease severity, complicates treatment strategies, and increases mortality rates. In this study, we developed a mathematical model of TB-HIV co-infection to examine the dynamics of TB prevalence, HIV prevalence, co-infection prevalence and combined …
Hoerter A, Arnett E, Schlesinger LS, Pienaar E
…y between Mycobacterium tuberculosis ( Mtb ) and HIV during coinfection include: disruption of cytokine balances, impairment of innate and adaptive immune cell functionality, and Mtb -induced increase in HIV viral loads. Tuberculosis granulomas are the interface of host-pathogen …
Renu Kumari, Priyamvada Roy, Shalini Malhotra, Ulka Kamble, Nirmaljit Kaur
…to HIV-positive patients without TB following six months of treatment with anti-tuberculosis therapy (ATT) and antiretroviral therapy (ART). This study aims to assess absolute CD4 counts and the percentage of recovery in TB-HIV co-infected patients prior to starting antituberculo…
Bhering M, Duarte R, Kritski A
…h worldwide in the number of TB cases and 19 th in terms of TB-HIV co-infected cases. This study aims at identifying clinical and demographic factors associated with unsuccessful treatment outcomes (loss to follow-up, treatment failure and death) of HIV-positive patients with mul…
Kegne TW, Anteneh ZA, Bayeh TL, Shiferaw BM, Tamiru DH
…predictors of mortality were not sufficiently studied among TB-HIV co-infected patients in Ethiopia. Objective This study aimed to investigate the survival rate and predictors of mortality among TB-HIV co-infected patients during TB treatment at public health facilities in Bahir …
Demitto FO, Schmaltz CAS, Sant'Anna FM, Arriaga MB, Andrade BB, et al.
…ns to treat both diseases concomitantly. Nevertheless, some TB-HIV patients undertaking ARVs (ARV-experienced) are already failing the first line efavirenz-based regimen and seem to display different response to second line ARV therapy and exhibit other predictors of mortality. M…
Mekonen H, Negesse A, Dessie G, Dessie G, Desta M, et al.
…spite the implementation of a short-term direct observation treatment programme, HIV coinfection is one of the main determinants of tuberculosis (TB) treatment success. This meta-analysis was conducted to report the impact of HIV on TB treatment outcomes using inconsistent and va…
Aung ZZ, Saw YM, Saw TN, Oo N, Aye HNN, et al.
…with the highest burden of tuberculosis and HIV infections (TB-HIV) in the world. However, the survival rate and risk factors for mortality among TB-HIV co-infected patients in the country remain unstudied. Therefore, the purpose of this study was to examine these factors. Method…
Padayatchi N, Bionghi N, Osman F, Naidu N, Ndjeka N, et al.
…d with HIV drug-resistant tuberculosis (DR-TB). We compared treatment outcomes in DR-TB patients treated with BDQ- and linezolid (LZD) containing regimens to historic controls treated with second-line injectable-containing regimens. METHODS: Retrospective cohort study of consecut…
P. O. (Peter) Adediji, M. B. (Muideen) Olatunji, S. O. (Samuel) Okijiola, A. G. (Alimi) Annabelle, J. A. (Judith) Arachie
…e perceptions and awareness of risk factors associated with TB-HIV coinfection among healthcare attendees in Ibadan, Nigeria. The participant gender distribution in this study was relatively balanced, with women possibly demonstrating higher health awareness. TB/HIV knowledge was…