Showing 26–50 of 79 documents
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Widiyanti M, Adiningsih S, Kridaningsih TN, Fitrianingtyas R
…uses mortality among People Living with HIV (PLHIV), so the treatment of TB-HIV coinfection is crucial. The study aimed to identify the determinants contributing to TB coinfection among PLHIV in Papua. It is a descriptive-analytic study with a cross-sectional design involving 188…
Vonasek BJ, Rabie H, Hesseling AC, Garcia-Prats AJ
…ally. However, advances in children have lagged behind, and TB-HIV coinfection continues to be a major driver of pediatric mortality in many settings. This review highlights recent research findings in the areas of prevention, diagnosis, and treatment of HIV-associated childhood …
Kassaw A, Kefale D, Aytenew TM, Azmeraw M, Agimas MC, et al.
…national pooled proportion and incidence of mortality among TB-HIV co-infected patients were considered to be still high. The authors strongly recommended scale up and continuous provision of cotrimoxazole and isoniazid preventive therapy. In addition, early identification and tr…
Nardotto GHB, Bollela VR, Rocha A, Della Pasqua O, Lanchote VL
…iving with HIV. This study aims to assess the effect of HIV coinfection and antiviral therapy on the plasma exposure to FLATDs in patients with TB. HIV negative (TB-HIV- group; n = 15) and HIV positive (TB-HIV+ group; n = 18) adult patients with TB were enrolled during the second…
Gemechu LL, Debusho LK
…a; there is, however, no information on spatial patterns of TB-HIV coinfection in the country at the districts level at least using yearly data. This paper, therefore, aimed at determining the spatial clustering of TB-HIV coinfection prevalence rates in the country at the distric…
López-Medina EM, Sainz T, de Ory SJ, Mellado-Peña MJ, González-Tomé MI, et al.
…ribe the changing epidemiology and clinical presentation of TB-HIV co-infection in a cohort of HIV-infected children in Spain. METHODS: Children diagnosed with TB between 1995 and 2016 in the paediatric HIV cohort were identified. The incidence and clinical presentation were comp…
Tamene W, Abebe M, Wassie L, Mollalign H, Bauer K, et al.
… microbial products have not been well studied. Method HIV (TB-HIV+), TB (TB+HIV-) and TB/HIV co-infected (TB+HIV+) patients as well as apparently healthy controls (TB-HIV-) were recruited. TB and HIV patients were treatment naïve while TB/HIV patients were both ART naïve and exp…
Winter JR, Stagg HR, Smith CJ, Lalor MK, Davidson JA, et al.
… (17.2%). Conclusions There has been an overall decrease in TB-HIV co-infection and a decline in the proportion of patients diagnosed simultaneously with both infections. However, high rates of HIV remain in some sub-populations of patients with TB, particularly black Africans bo…
Madan C, Chopra KK, Satyanarayana S, Surie D, Chadha V, et al.
…man immunodeficiency virus (HIV) co-infection have worse TB treatment outcomes compared to patients with TB alone. The distribution of unfavourable treatment outcomes differs by socio-demographic and clinical characteristics, allowing for early identification of patients at risk.…
Adamu AL, Aliyu MH, Galadanci NA, Musa BM, Lawan UM, et al.
Background Successful tuberculosis (TB) treatment is essential to effective TB control. TB-HIV coinfection, social determinants and access to services influenced by rural residence can affect treatment outcome. We examined the separate and joint effects of rural residence and HIV…
Enimil A, Antwi S, Yang H, Dompreh A, Alghamdi WA, et al.
…er than 3 years old (young children) with tuberculosis (TB) coinfection. To date, there are insufficient data to recommend nevirapine-based therapy during first-line antituberculosis (anti-TB) therapy in young children. We compared nevirapine pharmacokinetics (PK) in HIV-infected…
Wyrsch F, von Braun A, Sekaggya-Wiltshire C, Haller S, Ledergerber B, et al.
…d TB drug levels were obtained at Week 0, 2, 8 and 24 of TB treatment. RESULTS: A total of 107 patients were included in this analysis. Random plasma glucose ≥200 mg/dL was found in 1/53 (2%) participant at Week 0. The prevalence of FPG ≥ 126 mg/dL decreased from 8/41 (20%) at We…
Gbeasor-Komlanvi FA, Sadio AJ, Adama OI, Zida-Compaore WIC, Tchankoni MK, et al.
BACKGROUND: Good adherence is essential in the treatment of TB. The aim of this study was to describe medication consumption patterns and to assess factors associated with adherence to TB treatment among TB patients in Lomé, Togo. METHODS: A cross-sectional study was conducted am…
Byamungu LN, du Preez K, Walters E, Nachega JB, Schaaf HS
…diagnoses in children. Design Retrospective cohort study in TB-HIV co-infected children aged Results Of 88 children with TB-HIV co-infection, 37 (42%) had a simultaneous TB-HIV diagnosis; 51 children had been known to have HIV before their TB diagnosis. Interruption of antiretrov…
Chittamany P, Yamanaka T, Suthepmany S, Sorsavanh T, Siphanthong P, et al.
…patients incur large costs for care seeking, diagnosis, and treatment. To understand the magnitude of this financial burden and its main cost drivers, the Lao People's Democratic Republic (PDR) National TB Programme carried out the first national TB patient cost survey in 2018-20…
Amirkhani A, Humayun M, Ye W, Worku Y, Yang Z
…identified prison TB research as a top priority to guide TB treatment/control interventions. Methods We retrospectively analyzed 921 notified TB cases that were diagnosed at Kality Federal Prison, Ethiopia during 2009-2017. To assess trends of microbiologically confirmed pulmonar…
Amelo Bolka, Selamawit Sikuare, Assefa Philipos Kare, Fentaw Wassie Feleke, Tafese Bosha
…ry diversity (APR = 1.56; 95% CI: 1.21-2.01), TB-HIV coinfection (APR = 1.65; 95% CI: 1.23-2.21), and parasite infection (APR = 1.78; 95% CI: 1.41-2.25). The identified predictors of anemia among PWTB were food insecurity (APR =&#x…
Ufoaroh CU, Anyabolu EN, Okoye IC, Chinweuba IS
…global healthcare problem. In Sub-Saharan African countries TB-HIV co-infection is an evil duo. This study sought to evaluate TB characterization and mortality rate in TB subjects in a semi-urban tuberculosis center in Southeast Nigeria. Methodology This was a retrospective study…
Gabriela Tavares Magnabosco, Fernanda de Paulo Pedroso, Isadora Gabriella Silva Palmieri, Letícia Baio de Souza, Heitor Hortensi Sesnik, et al.
In Brazil, tuberculosis-human immunodeficiency virus (TB-HIV) coinfection remains a major public health challenge despite advances in antiretroviral therapy and tuberculosis preventive treatment (TPT) Civil society has historically contributed to HIV responses, but little is know…
Nabisere R, Musaazi J, Denti P, Aber F, Lamorde M, et al.
…py, although very effective, has limitations including long-treatment duration with a possibility of non-adherence, drug interactions, and toxicities. Dose escalation of rifampicin, an important drug within the regimen, has been proposed as a potential route to higher treatment e…
Yang H, Antwi S, Maranchick N, Dompreh A, Amissah AK, et al.
… to address these questions. DESIGN/METHODS: Children on TB treatment were enrolled. After 4 weeks on therapy, blood samples were collected at pre-dose, 1, 2, 4, 8, and 12 h post-dose for pharmacokinetic analysis. Plasma drug exposure below and above the lower and upper bounds of…
Skouvig Pedersen O, Barkholt TØ, Horskær Madsen S, Rudolf F
…resent the case of a patient with HIV and tuberculosis (TB) coinfection who initially developed paradoxical TB immune reconstitution inflammatory syndrome (TB-IRIS) post-antituberculous treatment and post-antiretroviral therapy initiation. Despite being managed effectively, lymph…
Safe IP, Amaral EP, Araújo-Pereira M, Lacerda MVG, Printes VS, et al.
…C as adjunct therapy during the first two months of anti-TB treatment was safe. Whether adjunct NAC therapy of patients with TB-HIV coinfection in the context of anti-TB treatment could directly affect pro-oxidation and systemic inflammation has not been yet formally demonstrated…
Villalva-Serra K, Barreto-Duarte B, Rodrigues MM, Queiroz ATL, Martinez L, et al.
…cenarios. Findings Vulnerabilities including incarceration, TB-HIV coinfection and TB-diabetes mellitus, as well as coverages of directly observed therapy (DOT), contact investigation and preventive treatment (TPT) completion rates, were identified as key predictors of TB inciden…
Carroll A, Vincenti-Delmas M, Maung BM, Htun WPP, Nosten F, et al.
…B programme. METHODS: Routinely collected data on TB cases, treatment outcomes and causes of death were analysed for adult TB cases diagnosed between January 2013 and April 2017. Mortality in the 6 months post-diagnosis was calculated and risk factors were identified using multiv…