Showing 176–200 of 200 documents
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Felipe Ridolfi, Gustavo Amorim, Lauren Peetluk, David W. Haas, Cody Staats, et al.
Abstract Background Tuberculosis (TB) treatment-related adverse drug reactions (TB-ADR) can negatively affect adherence and treatment success rates. Methods We developed two prediction models for TB-ADR. We included drug-susceptible pulmonary TB participants who initiated standar…
V.B. Avdentova, E.M. Belilovsky, Borisov Se, E. M. Bogorodskaya, O. N. Zuban, et al.
…ics with unfavourable treatment outcomes of adult pulmonary tuberculosis (TB) without multidrug resistance in a region with low epidemiological rates. Methods. We studied treatment outcomes in 887 drug-susceptible pulmonary TB patients aged over 17 years. We used univariate analy…
Nava Ruelas, Rocio del Rosario
…ckground: Depression is a common comorbidity in people with tuberculosis (TB). Treating depression in people with other conditions often improves both physical and mental health outcomes. However, the impact of treating depression in people with TB on their mental health and TB-r…
Lena Faust
The COVID-19 pandemic has disrupted tuberculosis (TB) services globally. Measuring the extent of these disruptions is critical to mitigate their impact and provide valuable information for TB program improvement, particularly in settings hard-hit by both COVID-19 and TB, such as …
Muhammad Abdul Hadi
…mal doses of first-line drugs for treating drug-susceptible tuberculosis in children and adolescents are still uncertain.
 Aim: The purpose of this study was to determine whether children treated with recommended or increased doses of first-line drugs achieve successful outc…
Liza Khutsishvili, Carolin Fabian, Kennedy Ngowi, Margaretha Sariko, Krisanta Wilhelm, et al.
… care interventions remain largely untapped for people with tuberculosis (TB) in many settings. A smartphone platform adopted to support treatment of human immunodeficiency virus (HIV) in the US was adapted and piloted for HIV/TB care in a distinct urban population, with high usa…
Lisa Redwood
…e greater need for integration of mental health services in tuberculosis care.I thought
Edwin Nuwagira, Stellah Mpagama, Conrad Muzoora, Joseph Mugerwa, Mike Ssemusu, et al.
Abstract Rationale: Tuberculosis remains a public health tragedy with more than ten million people infected per year, majority of whom are from low and middle income settings. Malnutrition and HIV remain the leading risk factors for TB infection. Despite the advocacy and awarenes…
Jonas Michel Wolf
…rminants of depression among patients with drug-susceptible tuberculosis (TB) in Ogbomoso, Nigeria.By drawing attention to the intersection between infectious diseases and mental health, the research highlights a crucial but often neglected domain of TB management.The introductor…
Sang Chul Lee, Jae Kwang Lee, Jung Mo Lee, Seon Cheol Park, Chang Hoon Han
… Political change regarding for exemption of co-payment for tuberculosis (TB) treatment was made in July 2016. We investigated the effect of the co-payment waiver on long-term treatment interruption and clinical outcomes among pulmonary TB patients in South Korea. Methods Patient…
Anthony Byrne, R Wong, D Marriott, D Kocic, J Alffenaar, et al.
…tility, therapeutic drug monitoring (TDM) for Mycobacterium tuberculosis (TB) is not available in many settings including New South Wales (NSW). <b>Objectives:</b> Establish a TDM assay for clinical use amongst drug susceptible-TB patients in Sydney and evaluate its acceptance an…
Human Sciences Research Council
Poor-quality tuberculosis (TB) care is now a larger barrier to reducing mortality than poor access. South Africa (SA) has one of the highest TB burdens globally. Despite ongoing efforts to improve access to testing and treatment in primary care settings, only half of South Africa…
Bahirdar University
…nual is organized to improve knowledge and attitude towards tuberculosis, to reduce social stigma and to strengthen TB control and prevention strategies
Oriekot Anthony, Senai Goitom Sereke, Felix Bongomin, Samuel Bugeza, Zeridah Muyinda
Abstract Background: Tuberculosis (TB) is one of the leading causes of death worldwide. Radiology has an important role in the diagnosis of both drug-sensitive (DS) and drug-resistant (DR) pulmonary TB (PTB). This study aimed at comparing the chest x-ray (CXR) patterns of microbi…
Linh Nguyen, Kerri Viney, Medea Gegia, Dennis Falzon, Philippe Glaziou, et al.
<b>In 2021, WHO revised its tuberculosis treatment outcome definitions, making them uniformly applicable for different lengths of treatment for both drug-susceptible and drug-resistant disease</b>https://bit.ly/3jFFgOu
Ao Xu, Zexuan Wen, Yue Wang, Weibing Wang
Abstract Background. Tuberculosis (TB) is one of the top ten causes of death worldwide. The World Health Organization adopted the “End TB Strategy”, whose goal is to end the global TB epidemic by 2035. However, achieving this goal will be difficult using current prevention and co…
Christopher A. Berger, R. Crowder, A. Kityamuwesi, Noah Kiwanuka, M. Lamunu, et al.
Background: Tuberculosis (TB) treatment completion rates are below global targets. 99DOTS is a low-cost digital adherence technology (DAT) that could increase TB treatment completion. Methods: We conducted a pragmatic, stepped-wedge cluster randomized trial including all adults t…
Silvia S. Chiang, Helen E. Jenkins
Tuberculosis (TB) kills ∼1.5 million people worldwide each year.1 Among children and adolescents infected with TB, those <5 years old and those with HIV coinfection have a higher risk of death.2–4 Not only have few researchers quantified the impact of antiretroviral therapy (ART)…
Rajendra Prasad, Abhijeet Singh, Nikhil Gupta
Drug-susceptible tuberculosis (DS-TB) requires treatment with first-line drugs (FLDs) whereas drug-resistant TB (DR-TB) are treated with combination of second-line drugs (SLDs) and fewer FLDs. Adverse drug reactions (ADRs) to these drugs are quite evident as they are being used f…
World Health Organization. Regional Office for Europe
One key aim of tuberculosis (TB) prevention and care is to render them more people-centred, which means further boosting and improving ambulatory care models across the countries of eastern Europe and central Asia. This note is intended to remind interested parties of the evidenc…
Gates MRI
…s safe and effective in treating drug-susceptible pulmonary tuberculosis.
Beatrice Kirubi, Jane Rahedi Ong’ang’o, Peter Nguhiu, Knut Lönnroth, Aiban Rono, et al.
…stract Background: Despite free diagnosis and treatment for Tuberculosis (TB), the costs during treatment impose a significant financial burden on patients and their households. Aim : The study sought to identify the determinants for catastrophic costs among patients with drug-se…
Nelly Solomonia, K Vacharadze
…ever identification of susceptibility to the different anti-Tuberculosis (TB) drugs in different time period, not in all cases gives us opportunity to simultaneously know susceptibility to the all anti-TB drugs and to build an appropriate treatment regimens based on complete indi…
Naveen Pandhi, Ritu Dadra, Balbir Malhotra, Dr. P Prasanth
…dy, which included 200 microbiologically confirmed cases of tuberculosis (TB) which came to outpatient department or got admitted in the wards. Clinico-diagnostic profile of these cases was determined. The collected data were documented, compiled, tabulated and statistically anal…
M R Marll, M Magee, N Glover, T Ngwanto, N Mofokeng, et al.
Abstract Rationale Approximately half of all tuberculosis (TB) survivors develop post-TB lung disease (PTLD), defined as persistent respiratory abnormalities despite a microbiological cure. Fibrosis, which typically presents as a restrictive ventilatory impairment on pulmonary fu…