To Study the Pattern of Drug Resistance in Microbiologically Confirmed Cases of Tuberculosis and Risk Factors Associated with Drug Resistance

This is an observational prospective study, which included 200 microbiologically confirmed cases of tuberculosis (TB) which came to outpatient department or got admitted in the wards. Clinico-diagnostic profile of these cases was determined. The collected data were documented, compiled, tabulated and statistically analysed to reach a valid conclusion. Out of 200 microbiologically confirmed cases of TB, 25% of the cases were in the age group of 21-30 years, 147 (73.5%) were drug susceptible (DS) and 53 (26.5%) were drug resistant (DR). Amongst DR-TB cases, 21 (18.7%) were new and 32 (36.4%) were previously treated cases. Rifampicin mono-resistance was higher in both new (47.6%) and previously treated (37.5%) drug resistance cases. The majority of the patients with DR-TB had previous history of ATT i.e., (p value <0.5). Risk factors associated with DR-TB are female gender and previous history of Anti-tubercular therapy (ATT) (p value <.05).