Showing 176–200 of 200 documents
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Hyun-Eui Park, Jin-Sik Park, Hong-Tae Park, Jeong-Gyu Choi, Jeong-Ih Shin, et al.
(MAP), which induces persistent diarrhea and cachexia. JD causes huge economic losses to the dairy industry due to reduced milk production and premature culling. Infected animals excrete MAP via feces during the prolonged subclinical stage without exhibiting any clinical signs. T…
Isaac Dayo Olorunshola, Khaled Ahmad, A.R. Peters, R. A. J. Nicholas, David S. Adegboye
Abstract Mycoplasma bovis infections in cattle constitute a worldwide problem with significant detrimental economic impacts on cattle industry. Mastitis, pneumonia, arthritis, keratoconjunctivitis, otitis media and genital disorders are its clinical manifestations. Presently, no …
Rim Bayaa
La tuberculose (TB) reste l'une des principales causes de décès dans le monde. Il est essentiel de s'appuyer sur un diagnostic précoce et des biomarqueurs évaluant l’efficacité du traitement. L'Organisation mondiale de la santé (OMS) a déclaré un besoin urgent de tests alternatif…
Aditya Kumar Jha
…ar microscopy and culture have low sensitivity, so advanced diagnostics like PCR, histopathology, FNAC, and Xpert MTB/ RIF are needed. This study aimed to assess the clinical features and diagnostic accuracy of these methods in smear-negative cervical tuberculous lymphadenitis. M…
Christine Tzelios, Ruvandhi R. Nathavitharana
…OHigh-priority target product profiles for new tuberculosis diagnostics: report of a consensus meeting. World Health Organization, Geneva2014Google Scholar Above this sensitivity threshold, the receiver operating characteristic curves did not differ significantly between the five…
Maria Olivia Fotiou, Amelia Holloway, Anoop Kurian Mathew, Alexis Jones, Jessica Manson
Abstract Introduction Severe systemic lupus erythematosus (SLE) can present with multi-organ involvement, including respiratory manifestations. SLE can both mimic and trigger hyperinflammatory states, including haemophagocytic lymphohistiocytosis (HLH). This case describes a pati…
M Gonzalez, R Gupta, A Bint, I Munir, J Verma, et al.
Abstract Cavitary pulmonary lesions present a diagnostic challenge, particularly in patients with structural lung disease and immunologic vulnerability. We report the case of a 74-year-old male with severe COPD and a remote history of treated tuberculosis who presented with acute…
Mei Li, Yuxin Luo, Yuxin Luo, Wenqiang Li, Yiqing Wang, et al.
…onfigurable systems offer rapid, low‐cost, field‐deployable diagnostics. Modular nanosensors utilize functionalized interfaces to amplify trace biomarker capture, reduce interference, and enable multiplexing, advancing high‐sensitivity, low‐cost infectious disease diagnostics. It…
Shani Abidi, Handri Andika
Background: Tuberculosis (TB) remains a major global health challenge, with its variable clinical presentations often complicating timely and accurate diagnosis. Diagnostic imaging modalities such as chest X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and pos…
Abidemi Ojo, Seun Owolabi Adebajo, Olugbenga Ojo, Aderibigbe Ajibola, D. A. Ojo, et al.
Statement of the Problem: Tuberculosis remains a serious public-health threat in developing countries though it has been eradicated in some advanced countries. This disease constitutes a significant threat to global health, being the second highest cause of morbidity and mortalit…
Gayathri Ramasubban, Joy Sarojini Michael, Richa Gupta, Kavyasri Channamaneni, Dhanabagyam Krishnan, et al.
…developed to provide efficient, accurate, and accessible TB diagnostics. This study evaluates the performance of the mfloDx ™ pre-XDR-TB test for detecting TB and drug resistance against MGIT culture and drug susceptibility testing (DST). Methodology We have evaluated the perform…
Kato Jacob, Simon Peter Rugero, Mathias Tumwebaze, Mabuga William
Background: Diagnosing tuberculosis (TB) in HIV-positive patients on Antiretroviral Therapy (ART) remains challenging, especially in resource-limited settings. C-reactive protein (CRP) levels and TB LAM tests have been suggested as potential diagnostic tools. This study aimed to …
Filipa Jesus, Maria Francisca Barros, Ana Isabel Ribeiro, Óscar Felgueiras, Raquel Duarte
<bold>Introduction:</bold> Tuberculosis (TB) remains a global health concern and the COVID-19 pandemic has impacted the fight against TB, with delays in diagnosis. Timely diagnosis is crucial, with experts suggesting that diagnostic delay reflects the efficacy of TB programs. Des…
Declan Emegano, Nazife Sultanoğlu, Efe Precious Onakpojeruo, Berna Uzun, Dilber Uzun Ozsahin, et al.
BACKGROUND/AIMS: Latent tuberculosis infection (LTBI) remains a critical challenge in global tuberculosis (TB) control efforts, necessitating effective diagnostic techniques.This study provides a comprehensive analysis of 7 diagnostic methods for LTBI, including QuantiFERON-TB an…
Yuliya Mikhaylova, Nadezhda Mezentseva, С. А. Стерликов, Aleksandr Mikhaylov, Yana Pankova
Significance. The system of microbiological diagnostics is of key importance for organizing microbiological diagnostics in accordance with the modern recommendations, and fulfilling political commitments of the Russian Federation within the framework of the End TB Strategy Purpos…
Serge Diagbouga, Diakourga Arthur Djibougou, Camille Pease, Ariana Alcaide, Audrey Berthoux, et al.
ABSTRACT Importance Accurate diagnosis of tuberculosis (TB) infection can be achieved with interferon-γ release assays. Their performance can be improved by utilizing fully automated, single-patient formats. Objective Establish clinical thresholds for a new interferon-γ release a…
Abdurahmonova K.R, Xasanova S.T, Hoshimova Z.Y, Norboyeva S.Z
This article reviews modern diagnostic approaches to the study of tuberculosis (TB) infections and their clinical and epidemiological significance. The article analyzes the possibilities of detecting Mycobacterium tuberculosis using molecular-genetic methods, in particular polyme…
Sohail Hussain, Faiza Nafees Khan, Aimen Noor Ul Ain, Momina Shahid, Imtiaz Begum, et al.
Abstract Background Tuberculosis (TB) of the abdomen is a rare form of extrapulmonary TB with indeterminate symptoms that are commonly mistaken for malignancies, leading to substantial diagnostic problems. This report describes the intricacies of diagnosing abdominal TB and empha…
Abdurahmonova K.R, Xasanova S.T, Hoshimova Z.Y, Norboyeva S.Z
This article reviews modern diagnostic approaches to the study of tuberculosis (TB) infections and their clinical and epidemiological significance. The article analyzes the possibilities of detecting Mycobacterium tuberculosis using molecular-genetic methods, in particular polyme…
World Health Organization
…echnologies. The guidance applies to a broad range of rapid diagnostics, including tests for HIV, tuberculosis, malaria, SARS-CoV-2, hepatitis, syphilis and pregnancy, among others. The publication outlines practical considerations to improve accessibility and usability across l…
Elmira Ibraim, MD
…vestigators are aiming for the assessment of several new TB diagnostics (e.g. new AID strip assays and TrDNA assay in urine) in TB suspects who are presenting themselves to the pulmonary ambulance (TB dispensary for sector 4) at the Marius Nasta Institute (MNI). The study will be…
Khadka Priyatam, Kharel Ranju
Ocular tuberculosis is an exigent clinical entity—lacking a distinct clinical presentation and attributing the diagnostic conundrum. Nevertheless, the early-precise diagnosis with implicated anti-tubercular therapy may be sight-saving; diagnostic delays often encountered due to p…
Jay Prakash Yadav, Pankaj Dhaka, Maninder Singh
Mycobacterium bovis ( M. bovis ), the causative agent of bovine tuberculosis (bTB), is recognized as a significant zoonotic pathogen at the intersection of wildlife, livestock, and humans. This comprehensive review aims to evaluate the prevalence of bTB in naturally infected wild…
Dissou AFFOLABI, MD, MSc, PhD
Recent advances in molecular diagnostics of tuberculosis, especially the GeneXpert Mycobacterium tuberculosis/Rifampicin test have reduced the time to diagnose Rifampicin Resistant Tuberculosis (RR-TB) but only rifampicin resistance is diagnosed, leading to presumptive diagnosis …
Courtney M. Yuen, Ana Karina Millones, David Acosta-Silva, Isabel Torres, Sheyla Farroñay, et al.
SETTING: Lima, Peru. OBJECTIVE: To close the gap in TB diagnosis, TB diagnostic services must match care-seeking preferences. We sought to identify preferred strategies for delivering TB diagnostic services and to determine whether preferences differ among demographic groups. DES…