Showing 101–125 of 200 documents
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Rafaela Baroni Aurílio, Adriana Rodrigues Fonseca, Ana Alice Amaral Ibiapina Parente, Maria de Fátima B. Pombo March, Marta Cristine Félix Rodrigues, et al.
Tuberculosis (TB) and reactivation of latent tuberculosis infection (LTBI) remains a major concern in patients with rheumatic diseases due to immune dysregulation and immunosuppressive and biological treatment, especially in a high-burden TB country. Xpert® MTB/RIF (real-time PCR…
Yu Rim Lee, Heechul Park, Yun-Jeong Kang, Sung‐Bae Park, J. Kim, et al.
Objectives: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) bacteria.According to a World Health Organization report, a third of the world' s population has latent TB infection (LTBI), and 5%-10% of people with LTBI are at risk of developing …
Rosana Agus, Ian Imanuel Fidhatami, Mochammad Hatta
…er countries are included in High Burden Countries (HBC) in Tuberculosis (TB) cases. One of the problems in TB control in Indonesia is detecting latent TB appropriately. Diagnosis of latent TB does not have a gold standard. Some tests to detect latent TB have limitations in TB en…
Z. Mohamed, R.H. Pando, Mohd Nor Norazmi
Background: New effective tuberculosis (TB) vaccines are urgently needed to control the disease which infects about 10 million people and kills about 2 million people annually. The existing TB vaccine, Bacille Calmette Guerin (BCG), is the only available licenced vaccine which is…
Sabrina Prihantika S., Nova Kurniati, Kemas Yakub Rahadiyanto, Mgs. Irsan Saleh, Zen Hafy, et al.
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis which is still a health problem in the world including in Indonesia. TB infection arises due to interference with the regulation of the body's defense system. Cellular immune system play…
Yu Zhou, Yu Zhou, Haiping Lan, Hanlu Shi, Peihao Wu, et al.
Abstract Background: Tuberculosis (TB) is a leading global public health problem, but the mechanisms underlying the immunopathology of TB progression are not well understood. It is currently believed that Mycobacterium tuberculosis (Mtb) infection can modify NK cell phenotypic si…
Patricio Escalante, Kelly M. Pennington, Virginia P. Van Keulen, Courtney L. Erskine, Tobias Peikert
…ty with CA-antigens (CAAg) have been variable during latent tuberculosis infection (LTBI) screening. We hypothesized that the use of a CAAg in an ELISPOT assay would provide a positive control to study tuberculosis (TB)-antigen specific immune responses. Objective To test an ELIS…
Ananya S Willsraj, Suba Joice, Y Dishan, Blessed Singh, Ajin Chandran
Background and objectives: Latent tuberculosis infection (LTBI) affects one-third of all mankind and is the reservoir for a significant proportion of emerging active tuberculosis (TB) cases in the future. The detection and management of TB infection is one of the key components o…
Laura A. Vonnahme, Preeti Ravindhran, Julie Espey, Bhumika Sharma, Taylor Moore, et al.
Abstract Importance Tuberculosis (TB) was the leading infectious cause of death worldwide in 2023. Most US TB cases represent reactivation of latent TB infection (LTBI). Because LTBI treatment is approximately 90% effective for preventing TB disease, LTBI screening and treatment …
Rubens Camargo Siqueira, Fernando Oréfice
Precise detection of latent tuberculosis infection is becoming increasingly important due to increased use of immunosuppressive drugs and the human immunodeficiency virus epidemic , which increased the risk of reactivation to active tuberculosis (TB).The QuantiFERON® TB Gold IGRA…
Niaina Rakotosamimanana, Mark Doherty, Vaomalala Raharimanga, Vincent Richard, Brigitte Gicquel, et al.
…estimated to be latently infected (LTBI) with Mycobacterium tuberculosis (Mtb) and are at risk of progressing to contagious active tuberculosis. New TB vaccines and improved detection of LTBI are therefore urgently required for global TB control. As a first step towards these goa…
Dong Won Park, Yun Jin Kim, Yoon‐Kyoung Sung, Sung Jun Chung, Yoomi Yeo, et al.
… factor inhibitors (TNFI) treatment are screened for latent tuberculosis infection (LTBI) and receive appropriate treatment before initiating TNFI [1]. However, there are no well-designed real-world studies proving the effectiveness of this guideline for rheumatoid arthritis (RA)…
Xu Gao, Sifan Tian, Tonglei Guo, Marianthi Anna Kioumourtzoglou, Lei Gao
…that air pollution was associated with an increased risk of tuberculosis (TB), an infectious disease caused by bacillus Mycobacterium tuberculosis (MTB). However, the associations of air pollution with latent TB infection (LTBI) and subsequent active TB development have not yet b…
Nazia Tabassum Sheikh, Sameera Akhtar, Shazia Tabassum, Sumat Ul Khurshid
Background: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis and one of the major diseases affecting children throughout the world. Mantoux test and direct microscopic examination of acid-fast bacilli (AFB) by Ziehl–Neelsen staining are diagn…
The Pharmaceutical Society Of Korea, Seungjae Oh, Eun Joo Lee, Jin‐Won Kwon, Hyun Soon Sohn
…teadily decreasing, Korea has not yet completely eradicated tuberculosis (TB), strategies to prevent the spread of infection and manage active TB and latent tuberculosis infection (LTBI) are necessary. This study aimed to assess the knowledge, risk perception, and stigma related …
Hye Seong, Yun Jeong Lee, Jiyeon Seo, Hakjun Hyun, Jin Gu Yoon, et al.
Abstract Background As most of the tuberculosis (TB) cases occur from latent TB (LTBI) reactivation, effective therapeutic interventions for LTBI are crucial to national TB control. Age is one of the important factors affecting LTBI treatment and management. This study assessed t…
Bülent Kaya
…and CD4/CD8 ratios as markers for the progression of latent tuberculosis infection (LTBI) to active tuberculosis (TB) infection in HIV-positive patients followed in the Acquired Immunodeficiency Virus (HIV) Polyclinic of our hospital.
Silvia Paulino Ribeiro Albanese, Arlete Alves Nunes Fragoso da Costa, Flávia Meneguetti Pieri, Elaine Cristina Santos Alves, Danielle Talita dos Santos, et al.
…tuberculin test is a diagnostic method for detecting latent tuberculosis (TB) infection, especially among disease contact cases. The objective of this study was to analyze the prevalence and evolution of Mycobacterium tuberculosis infection among TB contact cases. METHODS : A ret…
Seran Cheon, Siho Kim, Cheon Hoo Jeon, Yu Mi Wi
…care workers (HCWs) into five groups based on Mycobacterium tuberculosis exposure risk and transmission impact, guiding initial and periodic TB screening. These classifications serve as the basis for initial and periodic TB screening. However, data regarding the actual exposure f…
Holly Meacham, Takaaki Kobayashi, Mohammed Alsuhaibani, Stephanie Holley, Michael B. Edmond, et al.
Background: The CDC recently updated recommendations on tuberculosis (TB) screening in healthcare facilities, suggesting the discontinuation of annual TB screening. However, hospitals may opt to continue based on their local TB epidemiology. We assessed TB infection control param…
Özlem Karakaş, İsmail Doğan, Serdar Can Güven, Şule Erel, Şükran Erten
…neffectiveness. The number of patients who underwent latent tuberculosisc infection (LTBI) screening before treatment was 37 (62.7%); the number of patients who received prophylaxis was 13 (22%). None of the patients receiving IL-1 antagonists developed active tuberculosis. Concl…
Naesinee Chaiear, Phanumas Kraisorn, Chatpong Ngarmchokwatta, Kiatichai Faksri, Yingrit Chantarasuk, et al.
…ct Introduction Hospital staff are at higher risk of latent tuberculosis infection (LTBI), but there is limited understanding of the real LTBI situation among the large hospital staff in Thailand. Objectives: 1) We investigated 1) the proportion of LTBI among hospital workers at …
Shireen Ashkar
Tuberculosis (TB) is an infectious pulmonary disease caused by the pathogen Mycobacterium tuberculosis (MTB). It is the leading cause of death from a single bacterial pathogen and second, only to COVID-19, as the deadliest infectious disease overall. In 2020 alone, approximately …
Thana Khawcharoenporn, Kongporn Noisang
Abstract Background Tuberculosis (TB) contact investigation is recommended for healthcare professionals (HCPs) after TB exposure. However, association between no participation in or incomplete contact investigation and subsequent TB development has not been well-described. This s…
Sumaiya Islam, Dona A. Kiriella, Olutobi Oridota, Avika Dixit
…tely 1.2 million children are estimated to be infected with tuberculosis (TB) worldwide. The World Health Organization (WHO) routinely updates guidelines for the treatment to lateen tuberculosis infection (LTBI) in children with the last update provided in 2020. The objective of …