ACTIVE TUBERCULOSIS AFTER NEGATIVE SCREENING BEFORE TREATMENT OF PEDIATRIC AUTOIMMUNE DISEASES - NEED FOR RE-SCREENING IN HIGH-BURDEN TUBERCULOSIS AREAS?
Rafaela Baroni Aurílio, Adriana Rodrigues Fonseca, Ana Alice Amaral Ibiapina Parente, Maria de Fátima B. Pombo March, Marta Cristine Félix Rodrigues, Rozana Gasparello de Almeida, Christianne Costa Diniz, Flávio Sztajnbok, et al. (10 authors)
Abstract
Tuberculosis (TB) and reactivation of latent tuberculosis infection (LTBI) remains a major concern in patients with rheumatic diseases due to immune dysregulation and immunosuppressive and biological treatment, especially in a high-burden TB country. Xpert® MTB/RIF (real-time PCR-based molecular test) and culture are recommended to suspected TB cases, whenever it can be performed. This study aims to report a case series of pediatric patients with autoimmune rheumatic diseases, diagnosed with active TB in 2019, in a tertiary referral center in Pediatric Rheumatology and Pulmonology.
MeSH terms
- Medicine
- Tuberculosis
- Rheumatology
- Pulmonology
- Latent tuberculosis
- Internal medicine
- Active tuberculosis
- Immunology
- Mycobacterium tuberculosis
- Pediatrics