Showing 101–125 of 200 documents
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Etthel M. Windels, Eddie M. Wampande, Moses Joloba, W. Henry Boom, Galo A. Goig, et al.
Abstract Persons living with HIV are known to be at increased risk of developing tuberculosis (TB) disease upon infection with Mycobacterium tuberculosis ( Mtb ). However, it has remained unclear how HIV co-infection affects subsequent Mtb transmission from these patients. Here, …
…etrics Abstract While tuberculosis (TB) is a risk factor in HIV-1-infected individuals, the mechanisms by which Mycobacterium tuberculosis (Mtb) worsens HIV-1 pathogenesis remain scarce. We showed that HIV-1 infection is exacerbated in macrophages exposed to TB-associated microen…
Maeva Dupont, Shanti Souriant, Luciana Balboa, Thien‐Phong Vu Manh, Karine Pingris, et al.
…etrics Abstract While tuberculosis (TB) is a risk factor in HIV-1-infected individuals, the mechanisms by which Mycobacterium tuberculosis (Mtb) worsens HIV-1 pathogenesis remain scarce. We showed that HIV-1 infection is exacerbated in macrophages exposed to TB-associated microen…
Huma Haider
…ica with a population of approximately 15 million. Malaria, HIV and tuberculosis (TB) remain important public health concerns in the country, despite significant progress over the past two decades. Malaria incidence has declined markedly between 2003 and 2019 (by 81% from 2003 to…
P. O. (Peter) Adediji, M. B. (Muideen) Olatunji, S. O. (Samuel) Okijiola, A. G. (Alimi) Annabelle, J. A. (Judith) Arachie
…mics of tuberculosis (TB) and human immunodeficiency virus (HIV). This co-occurrence, often referred to as the "cursed duet," exerts a devastating impact on individuals, families, communities, and populations. In Nigeria, one of the countries significantly affected, both TB and H…
Muhammad Adnan Shereen, Nadia Bashir, Abeer Kazmi, H. Qazi, Syeda Mehreen Hassan, et al.
Background: The human immunodeficiency virus (HIV) afflicts the immune system by annihilating the white blood cells. The infection of HIV can alter the epidemiology and clinical profile of tuberculosis (TB) in patients suffering from co-infection. The objectives of the current st…
Melati Silvanni N, Spartaco Santi, Sri Novita, L Dharma
…ulosis (TB) can co-occur with Human Immunodeficiency Virus (HIV). The inflammatory condition that accompany the infection causes the release of free radicals and Reactive Oxygen Species (ROS) which can affect the lipid profile through increase of lipid peroxidase. Previous studie…
Dina Bisara, Oster Suriani Simarmata, Novianti Novianti, Felly Philipus Senewe
…tuberculosis is the most serious opportunistic infection in HIV/AIDS subjects and is a major cause of mortality and morbidity in developing countries. Objective: To describe the results of HIV / TB examination in Merauke District Hospital Method: Study design is cross-sectional u…
Tammy Meyers, MD, Paul Krogstad, MD
People who are infected with HIV and tuberculosis (TB) need to receive medications that treat both diseases safely and effectively. This study enrolled infants and children infected with HIV and TB and evaluated the safety and tolerance of an antiretroviral (ARV) treatment regime…
Amy Y Vittor, MD PHD
…erculosis (TB) is one opportunistic infection often seen in HIV individuals. In 2013, there were an estimated 31,800 HIV-TB co-infection cases and 6,100 HIV-related deaths due to TB in the Americas. Due to the non-specific nature of its clinical symptoms, TB can be confused with …
Epicentre
…m samples from adult pulmonary TB suspects in a high TB and HIV prevalence setting, using LJ and MGIT culture as gold standard. The Secondary objectives are: * To measure the performance of each assay (NRA, NRA-p, REMA-p) in sputum smear-negative patients * To describe the resu…
Human Sciences Research Council
…d South Africa has high burdens of tuberculosis (TB) and TB-HIV, yet the quality of patient care in the private sector is unknown. We describe quality of TB and TB-HIV care among private general practitioners (GPs) in two South African cities using standardised patients (SPs). Me…
Dian Natasya Rahardjo, Stefannie Sherine Santoso, Retnosari Andrajati, Ratu Ayu Dewi Sartika, Mariana Wahjudi
…roduction: Indonesia is one of the countries with a high TB-HIV prevalence. Antiretroviral treatment (ART) is only being administered to approximately 42% of TB-HIV patients. The low utilization of ART can be attributed, in part, to the delayed initiation of treatment. Nonetheles…
Puspita Kristina Kusumawati, Lintang Dian Saraswati, Martini Martini, Retno Hestiningsih
HIV and Tuberculosis are two public health problems of global concern. People living with HIV (PLWH), can develop opportunistic infections because they do not know their HIV status. With the vulnerability of PLWH to opportunistic infections, especially TB, it is necessary to rout…
Keertan Dheda, MBChB, PhD
TB kills most people with HIV in Africa. TB is out of control. Radically different approaches to deal with the disease is therefor needed. It is known that intensified case finding works in high HIV prevalence environments. However, the poor performance of conventional diagnostic…
Amelia Stanton, PhD
…IT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among individuals with HIV and/or TB in Cape Town, South Africa. If feasibility, acceptability, and preliminary efficacy are demonstrated, the intervention will be ready for large-scale effectiv…
Uzochukwu Godswill Ekeleme, Ikenna Oluebube Ogini, Stanley Chinedu Eneh, Ugonma Winnie Dozie, Stephanie Adiruo Akunna, et al.
Nearly 90% of children living with HIV and tuberculosis are domiciled in Sub-Saharan Africa. Given the paucity of data on TB-HIV co-infection in children, this study aimed to understand the factors associated with co-infection in children receiving antiretroviral therapy (ART) in…
Human Sciences Research Council
…ive immunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process but has not been systematically studied in …
Marziye Kazerani, Fatemeh Abedi
HIV-TB co-infection is a major public health threat. HIV complicates every aspect of TB including presentation. The aim of this study was the assessment of some epidemiologic factors HIV-TB co-infection in patients referred to the infection- behavioral disorders center of Mashhad…
Nitya Vyas, Jyotsna Chandwani, Sakshee Gupta, Babita Sharma
…etiology during the course of human immunodeficiency virus (HIV) infection. High burden of tuberculosis (TB) among HIV-infected patients leads to lowering of immunity, thus increasing the incidence of other opportunistic infections. The present study was conducted to discuss the …
Uma Malik, Ghulam Rajput, Dsasui Tunio
A major global health concern is the co-infection of HIV/AIDS and TB, which increases rates of morbidity and mortality. The mortality ratios linked to HIV with TB co-infection are examined in this article through an analysis of epidemiological data of one window Service Treatment…
Suraj Abdulkarim, Stephen John, Tomon Garba, Hunpiya Basason, Paul Balogun, et al.
…icating (dormant) state and the increasing global burden of HIV coinfection. Consequently, understanding the knowledge and perception of the population at risk of tuberculosis-HIV infection is essential to designing a strategy of intervention embraced by the target population. A …
Christopher C. Whalen, MD, Roy Mugerwa, MD, Diane Havlir, MD
…his study is designed to determine whether 6 months of anti-HIV drugs given along with tuberculosis treatment will delay the onset of AIDS in HIV infected African patients. Tuberculosis (TB) is a common and serious complication of HIV infection in the developing world, especiall…
Arsalan Ahmed Uqaili, Marvi Gurbakhshani, Zahid Ali Shaikh, Imdad Ali Ansari, Keenjhar Gurbakhshani
…tors for hepatotoxicity among Human Immunodeficiency Virus- (HIV-) positive, tuberculosis (TB), and HIV/TB patients on treatment. This was a prospective follow-up study involving 125 participants from the HIV/AIDS and TB treatment centres in Tertiary Care hospital of Larkana and S…
E. I. Veselova, Anna Panova, Grigory Kaminskiy, Vadim Testov, Anastasia Samoilova, et al.
…osis (MTB) DNA and DST. It is critical important for TB and HIV co-infected patients due to acute and severe TB manifestation. <b>Aims:</b> To study efficiency of MTB DNA detection (MTBD) by MGM among new TB cases with HIV positive (HIV+) and HIV negative (HIV-) status. <b>Method…