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World Health Organization
…entation guide provides operational guidance for conducting tuberculosis (TB) epidemiological reviews and assessments of TB surveillance and vital registration systems within the framework of national TB programme reviews. The document describes the rationale, objectives and meth…
Lynn Sosa, Gibril J. Njie, Mark N. Lobato, Sapna Bamrah Morris, William G. Buchta, et al.
…dated recommendations for screening health care workers for tuberculosis, including eliminating serial screening in the absence of exposure or ongoing transmission. This article presents updated recommendations for screening health care workers for tuberculosis, including elimina…
Delia Goletti, Seif Al-Abri, Giovanni Battista Migliori, Cecilia S. Lindestam Arlehamn, Pranabashis Haldar, et al.
Every year, World Tuberculosis (TB) Day is commemorated on March 24 and is targeted at raising public and political awareness of TB, a preventable and treatable disease. World TB Day commemorates the day in 1882 when Professor Robert Koch announced his discovery of the microbial …
Michael Lauzardo, Meghan Nodurft-Froman
Until recently, tuberculosis in children has received little attention from the international public health community, despite it being a key sentinel event indicating recent transmission and hence a window into efforts to control transmission.1Shingadia D Novelli V Diagnosis and…
Eskild Petersen, Martin Rao, Giuseppe Ippolito, Gina Gualano, Jeremiah Chakaya, et al.
Tuberculosis today remains the world's number one cause of death from an infectious disease (WHO, 2018aWHO World Health Organization. Global tuberculosis report.2018Google Scholar). According to data from the World Health Organization Global Tuberculosis Report (WHO, 2018aWHO Wor…
María Vitale
Mycobacterium bovis is considered the proxy for zoonotic tuberculosis by international health organisations. However, in a large screening study of 940 mycobacteria-positive cultures from hospitalised patients, mainly from India and some from Bangladesh and Nepal, Shannon C Duffy…
Anthony Kodzo-Grey Venyo
Cases of tuberculosis of the testis, epididymis, scrotum and or the penis including the urethra are very rare even though pulmonary tuberculosis is common globally. In view of the fact that tuberculosis of the scrotum and scrotal contents and penis is rare, it would be envisaged …
Douglas Wilson, Patrick Cudahy, Paul K. Drain
Clinicians need improved tests to diagnose tuberculosis, especially in people living with HIV. Sputum-based molecular tests (eg, the Xpert MTB/RIF and Xpert Ultra assays, Cepheid, Sunnyvale, CA, USA) perform well in adults with presumptive tuberculosis who are HIV-positive (ie, s…
MV Smilianska, AY Volianskyi, LA Sukhanova, NV Kashpur
…ades, great changes have taken place in the epidemiology of tuberculosis (TB), which are reflected in the change in the statistical indicators of the spread of tuberculosis, due to both the infectious and social nature of the disease. At the end of the 20th century, after a long …
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 3: Supplemental database 3. Global ANOVA analysis to identify the proteins that showed significant differences among the eight groups (HC, LTBI, NTM, and TB) in plasma samples with and without stimulation. To perform the quantization analysis, the LFQ values of ea…
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 2: Supplemental dataset S2. Differentially abundance values of proteins comparing four groups (HC, LTBI, NTM and active TB) to each other’s measured from analyzed in two technical replicates computing the abundances with the MaxLFQ software tool. The analytes were…
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 4: Supplemental dataset S4. Independent-sample t-tests to identify proteins that were up-regulated or down-regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail. Fifty-nine proteins were significantly regulated upon stimulation with the ESAT-6/CFP-10 …
V. S. Krutko, L. H. Nikolaieva, Tetiana Maistat, О.A. Oparin, Anton Rohozhyn
Tuberculosis is infectious and socially dependent disease, being now one of the most pressing issues in practical health care. As well the usual types of tuberculosis infection, chemoresistant tuberculosis is spreading rapidly in the world. The WHO estimates that about 500,000 pe…
A.R. Aroyan, А. В. Мордык
Introduction . Extrapulmonary tuberculosis is more difficult to diagnose than respiratory tuberculosis. However, late detection leads to disabling consequences. Children from 4 to 11 years old are at risk for tuberculosis due to increased communication skills. It seems relevant t…
O.I. Sakhelashvili–Bil
Objective — to study the features of multidrug-resistant tuberculosis of the lungs of respiratory organs in children and adolescents from focuses of chemoresistant tuberculosis infection. 
 Materials and methods. To study the features of the course of multidrug-resistant pul…
Ahmad al Jbawi, Mohammad Fadel, Fares Kahal, Michel Najjar, Sara Albuaini, et al.
Abstract Background : Tuberculosis (TB) is a major public health concern worldwide and is the 13th leading cause of death and the second deadliest infectious disease after COVID-19. ¹ Extrapulmonary tuberculosis (EPTB) cases accounted for 16% of the 7.5 million cases of TB worldw…
Prabha Desikan, Aseem Rangnekar, Nikita Panwalkar, Ram Prakash Punde, Sridhar Anand
…etection and treatment of drug resistance in extrapulmonary tuberculosis (EPTB) is a major challenge worldwide. Drug resistance in EPTB has not been studied extensively. However, patients with drug-resistant EPTB have been reported to have poor outcomes[1]. Rifampicin and isoniaz…
Ravindra Y Mandolikar, Raju Hanumant Patil, Narendra Madhekar
Introduction: Tuberculosis is a chronic, communicable, infectious disease caused by Mycobacterium tuberculosis bacilli usually affecting lungs primarily resulting in pulmonary tuberculosis. Objective: to evaluate the Revised National Tuberculosis Control Programme (RNTCP) through…
Nilesh NamdeoGhule, Geeta Shiroor
The high incidence of Tuberculosis is a cause for concern and a huge threat to public health globally. The delays in case detection, diagnosis, health seeking, and non-adherence to treatment are some of the reason for the high Tuberculosis burden globally. In many tuberculosis Ce…
Leonardo Martínez, Neus Altet, F Boulahbal, Joan A. Caylà, Tsira Chakhaia, et al.
…t Objective To evaluate the impact of isoniazid on incident tuberculosis in household contacts of MDR tuberculosis cases. Design Systematic review and individual-participant meta-analysis. Data sources MEDLINE, Web of Science, BIOSIS, and Embase without language restrictions for …
Fernanda Bruzadelli Paulino da Costa, Mark P. Nicol, Maresa Botha, Lesley Workman, Ricardo Alexandre Arcêncio, et al.
BACKGROUND: Paediatric tuberculosis leads to more than 200 000 deaths annually. We aimed to investigate the incidence of Mycobacterium tuberculosis infection and tuberculosis disease in the first decade of life in the Drakenstein Child Health Study (DCHS), a South African cohort …
Shasha Hu, Qingzhu Wei, Yu Wu, Xin-Nian Li, Fujin Liu, et al.
BACKGROUND: Extrapulmonary tuberculosis (TB) is a relatively rare form of tuberculosis infection, accounting for approximately 15% of all tuberculosis infections. Lymph nodes are the most commonly affected sites, while involvement of the parotid gland is extremely rare. CASE PRES…
D. M. Kutuzova, T.E. Tyulkova, Valentina Tinkova
…enting with limited pulmonary damage, who were monitored in tuberculosis care institutions. Patients and Methods: a retrospective study was conducted based on medical record analysis of patients observed for tuberculosis in an antituberculosis dispensary during 2020–2021. Initial…
Olanisun P Adewole, MD, Bolanle A Omotoso, MD
Tuberculosis (TB) is caused by mycobacterial organism. It is the leading infectious disease cause of death globally, with more than 10 million new cases and over 2 million deaths annually. Developing countries bear the greatest brunt of the disease. The long duration of current t…
JAYA JAIN, Deepti Shrivastava
…CTION •There exists a lot of diagnostic dilemma for genital tuberculosis in the available literature No single test is found confirmatory except for wet culture and histopathological positivity which may become paucibacillary extrapulmonary sites and time consuming too. •Polymera…