Additional file 3 of Differences in plasma proteomes for active tuberculosis, latent tuberculosis and non-tuberculosis mycobacterial lung disease patients with and without ESAT-6/CFP10 stimulation

Additional file 3: Supplemental database 3. Global ANOVA analysis to identify the proteins that showed significant differences among the eight groups (HC, LTBI, NTM, and TB) in plasma samples with and without stimulation. To perform the quantization analysis, the LFQ values of each protein derived from MaxQuant were first log2 transformed and filtered to eliminate proteins with the most missing values. Missing values for other proteins were imputed and then multiple-samples test (ANOVA) was performed with Benjamini-Hochberg correction (FDR = 0.05), which led to 68 proteins that showed significant difference among the eight groups. P-values