TB Research

Additional file 4 of Differences in plasma proteomes for active tuberculosis, latent tuberculosis and non-tuberculosis mycobacterial lung disease patients with and without ESAT-6/CFP10 stimulation

Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, Mesfin Tamirat, Aboma Zewude, Temesgen Mohamed, et al. (13 authors)

Figshare · 2020-01

Abstract

Additional file 4: Supplemental dataset S4. Independent-sample t-tests to identify proteins that were up-regulated or down-regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail. Fifty-nine proteins were significantly regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail in HC, 36 proteins were significantly regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail in LTBI, and four proteins were differently regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail in NTM, eight proteins were significantly regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail in active TB. Columns in the Excel files designate technical replicates (donated by rep), t-test significant, comparison groups, P-value, q value, t-test difference, protein ID, protein names and gene names. P-values

MeSH terms

  • Tuberculosis
  • ESAT-6
  • Medicine
  • Latent tuberculosis
  • Disease
  • Mycobacterium tuberculosis
  • Lung disease
  • Stimulation
  • Lung
  • Immunology
  • Virology