Showing 126–150 of 200 documents
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V. R. Karthikayan, Anil Singh
…noma in a patient with multifocal small bowel strictures in tuberculosis endemic regions like India. Objective: The management of Small bowel adenocarcinoma is radically different from that of Intestinal tuberculosis and hence this article tries to highlight the importance …
A.S. Rodrigues, Elisabete Calabuig Chapina Ohara, Lívia Mendes Oliveira, Nathália Lima Souza
INTRODUCTION: Tuberculosis (TB) is still a major public health problem worldwide. It is estimated that in 2019, worldwide, about ten million people evolved with TB and 1.2 million died due to the disease. As for treatment outcomes, in 2018, the percentage of treatment success was…
Catherine Wilson
…use zoonotic disease. The main aim of eradication of bovine tuberculosis from countries where the disease is endemic has proved to be challenging. Mycobacteria can infect a very broad range of hosts. M. bovis, which is the main agent responsible for tuberculosis in domestic anima…
Marcos Henrique Teles Simão de Melo, Luana Bretas dos Santos Leonhardt, Jônatas Ferreira de Sá, Paulo Roberto Dias Bobenrieth
Pericardial tuberculosis is a rare and potentially fatal form of extrapulmonary tuberculosis that poses a diagnostic challenge, especially in endemic regions. This article reviews its clinical, epidemiological, and diagnostic aspects, based on literature published between 2012 an…
Keertan Dheda, Aliasgar Esmail, Anzaan Dippenaar, Robin M. Warren, Jennifer Furin, et al.
…ology, diagnosis, and clinical management of drug-resistant tuberculosis (DR-TB). Tuberculosis (TB) is far from eradicated and remains the foremost single infectious disease killer worldwide. Molecular epidemiology has played an important role in advancing our understanding of DR…
Fatma Tokgöz Akyıl, Kamil Janeczek
Tuberculosis (TB) is one of the leading causes of death worldwide and the most common cause of death from a single infectious agent. TB is caused by the droplet transmission of Mycobacterium tuberculosis (M. tuberculosis) bacilli, which sick people shed into the air. About a quar…
Özlem Abakay, Menduh Oruç
Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. Mycobacterium tuberculosis is transmitted by inhalation of droplets. Medication is the main component of TB treatment. When starting tuberculosis treatment, first a case definition is made and the treatment regi…
Soham Samajpaty
Mumbai Protocol is a shot in darkness in the field of tuberculosis research. At a time when clinicians around the world are obsessed with rifampicin to an extent of believing that no regimen against tuberculosis can work without it, the Mumbai protocol has opened a new avenue in …
Isma Yuniar, Aswin Wahyono, Heri Purnomo
The World Health Organization (WHO) declares Tuberculosis (TB) as a very important and serious public health problem throughout the world and is a disease that causes a global because in most countries in the world pulmonary TB disease is uncontrolled, this is caused by the numbe…
M Santhiya, N Ananya, Y Ashik Mohammed
According to global Tuberculosis report 2024 of World Health Organization (WHO), an estimated 10.8 million fell ill with Tuberculosis (TB) worldwide. To address these challenges, the study on Multimodal approach for early detection of Tuberculosis using Deep Learning, aims to dev…
Rafael Laniado-Laborín
…fetime risk of developing active TB in subjects with latent tuberculosis infection without the human immunodeficiency infection (HIV) co-infection is 5-10%; for people living with HIV (PLWHIV), the annual risk is 3-16% per year. The interaction of these two pathogens is complex: …
Kevin Flores-Lovon, Edwin Herrera, Paola Salinas, Rodney Macedo
Individuals who have co-infection with COVID-19 and tuberculosis (TB) are more likely to have severe illness and higher mortality. Thus, we sought to review the biological, immunological, clinical, and epidemiological interactions between COVID-19 viral infection and Mycobacteriu…
Meenu K. Sharma, Quinn Wonitowy, Hafid Soualhine
The Mycobacterium tuberculosis complex (MTBC) is comprised of species M. tuberculosis, M. bovis including M. bovis BCG (vaccine strain), M. caprae, M. pinnipedii, M. africanum, M. microti, M. canettii, “M. mungi”, and “M. orygis” (Woods et al., Susceptibility testing of mycobacte…
Mange Ram Yadav, Dushyant V. Patel, Divya Teli, Hiral Shah
Tuberculosis (TB) remains a substantial challenge for public health globally, impacting millions of individuals around the world. Despite extensive efforts to control the disease, it continues to pose a major public health challenge, involving therapeutic implications for multi-d…
Daniel L. Clemens
Mycobacterium tuberculosis subverts the normal membrane trafficking pathway of the host cell: it prevents the maturation and acidification of its phagosome, and thereby achieves a phagosome that is hospitable for its growth. The composition of the phagosome and the interactions b…
Guadalupe García-Elorriaga, Del Rey-Pineda Guillermo
Despite breakthroughs in tuberculosis (TB) laboratory detection over the last 30 years, only a small part of the global population has benefited. The World Health Organization (WHO) recommends using nucleic acid amplification tests (NAAT) to detect tuberculosis rather than smear …
Pankti C. Balar, Bedanta Bhattacharjee, Dixa A. Vaghela, Lalitkumar K. Vora, Vasso Apostolopoulos, et al.
Tuberculosis (TB) remains a global health challenge, necessitating innovative strategies to enhance prevention, diagnosis, and treatment. The present chapter explores cutting-edge developments in the field of TB control, with a specific focus on the pivotal roles played by vaccin…
Roxana Rustomjee
Abstract The failure to control tuberculosis (TB) in recent times stems, at least in part, from complacency towards TB control in the 1970s and 1980s and the subsequent devastating impact of the HIV-1 pandemic, the rising emergence of drug resistance as well as the growing dispar…
Andy Setiawan, Pramudya Pramudya, Hasyrin Ainun
Multidrug resistance tuberculosis (MDR-TB) is a form of tuberculosis bacterial resistance to at least two first-line anti-TB treatments, isoniazid and rifampicin, the two most effective TB medications.Treatment of Drug Resistant TB is set to be part of the national TB Control pro…
Andy Setiawan, Pramudya Pramudya, Hasyrin Ainun
Multidrug-resistant tuberculosis (MDR-TB) represents a strain of TB bacteria that exhibits resistance to a minimum of two primary anti-TB medications: Isoniazid and Rifampicin, both of which are regarded as the most potent drugs for combating TB.The management of drug-resistant T…
K. S. Mithra
Tuberculosis (TB) is one of the worst lung infections caused by bacteria called Mycobacterium tuberculosis. It is a disease that can be controlled in cases where it is quickly identified and treated. As sputum microscopy is a simple and low-cost approach, most countries use this …
Ramya Gopinath, Suthandira Munisamy, M. Jeyadevasena, Jacobson Jeffrey, Elanchezhiyan Manickan
…staining and smear microscopy employed for the diagnosis of tuberculosis (TB) have a significant disadvantage of poor sensitivity and the gold standard diagnostic method employing culture is time-consuming. This study was conducted to isolate and identify Mycobacterium tuberculos…
Dinara Adjablaeva
…ameters of children and adolescents with different forms of tuberculosis. Laboratory and instrumental methods of examination of patients do not cover all aspects of tuberculous infection and do not allow valuing the condition of children and adolescents with pulmonary tuberculosi…
Zahra Toossi, Larry S. Schlesinger
…tral role for mononuclear phagocytes in the pathogenesis of tuberculosis has been known for a century, the resurgence of tuberculosis in the United States and worldwide over the past two decades has lead to an equally impressive resurgence of research aimed at further defining th…
Tuberculosis (TB) infects one-third of the world population, and more than 80% of patients with active tuberculosis are HIV positive and at high risk of developing active disease. Intraocular TB constitutes a very small percentage of uveitis cases in North America and Europe (abo…