Showing 101–125 of 200 documents
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Yao S, Yan J, Li L, Ma D, Liu J, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) is currently a major problem in China. The prevention and treatment work for MDR-TB patients started late in Anhui province. To determine the prevalence of MDR-TB in sputum smear-positive TB patients (SSPTBPs) and analyze the r…
Plans-Rubió P, Godoy S, Toledo D, Domínguez A, Caylà J, et al.
…dy was to identify factors associated with non-adherence to tuberculosis (TB) preventive treatment among contacts with latent TB infection for new cases of pulmonary TB cases reported in Catalonia in 2019-2021. All contacts aged 18 years or older with a latent TB infection who re…
Lynn Sosa, Gibril J. Njie, Mark N. Lobato, Sapna Bamrah Morris, William G. Buchta, et al.
…dated recommendations for screening health care workers for tuberculosis, including eliminating serial screening in the absence of exposure or ongoing transmission. This article presents updated recommendations for screening health care workers for tuberculosis, including elimina…
Delia Goletti, Seif Al-Abri, Giovanni Battista Migliori, Cecilia S. Lindestam Arlehamn, Pranabashis Haldar, et al.
Every year, World Tuberculosis (TB) Day is commemorated on March 24 and is targeted at raising public and political awareness of TB, a preventable and treatable disease. World TB Day commemorates the day in 1882 when Professor Robert Koch announced his discovery of the microbial …
Michael Lauzardo, Meghan Nodurft-Froman
Until recently, tuberculosis in children has received little attention from the international public health community, despite it being a key sentinel event indicating recent transmission and hence a window into efforts to control transmission.1Shingadia D Novelli V Diagnosis and…
Eskild Petersen, Martin Rao, Giuseppe Ippolito, Gina Gualano, Jeremiah Chakaya, et al.
Tuberculosis today remains the world's number one cause of death from an infectious disease (WHO, 2018aWHO World Health Organization. Global tuberculosis report.2018Google Scholar). According to data from the World Health Organization Global Tuberculosis Report (WHO, 2018aWHO Wor…
María Vitale
Mycobacterium bovis is considered the proxy for zoonotic tuberculosis by international health organisations. However, in a large screening study of 940 mycobacteria-positive cultures from hospitalised patients, mainly from India and some from Bangladesh and Nepal, Shannon C Duffy…
Anthony Kodzo-Grey Venyo
Cases of tuberculosis of the testis, epididymis, scrotum and or the penis including the urethra are very rare even though pulmonary tuberculosis is common globally. In view of the fact that tuberculosis of the scrotum and scrotal contents and penis is rare, it would be envisaged …
Douglas Wilson, Patrick Cudahy, Paul K. Drain
Clinicians need improved tests to diagnose tuberculosis, especially in people living with HIV. Sputum-based molecular tests (eg, the Xpert MTB/RIF and Xpert Ultra assays, Cepheid, Sunnyvale, CA, USA) perform well in adults with presumptive tuberculosis who are HIV-positive (ie, s…
MV Smilianska, AY Volianskyi, LA Sukhanova, NV Kashpur
…ades, great changes have taken place in the epidemiology of tuberculosis (TB), which are reflected in the change in the statistical indicators of the spread of tuberculosis, due to both the infectious and social nature of the disease. At the end of the 20th century, after a long …
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 3: Supplemental database 3. Global ANOVA analysis to identify the proteins that showed significant differences among the eight groups (HC, LTBI, NTM, and TB) in plasma samples with and without stimulation. To perform the quantization analysis, the LFQ values of ea…
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 4: Supplemental dataset S4. Independent-sample t-tests to identify proteins that were up-regulated or down-regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail. Fifty-nine proteins were significantly regulated upon stimulation with the ESAT-6/CFP-10 …
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 2: Supplemental dataset S2. Differentially abundance values of proteins comparing four groups (HC, LTBI, NTM and active TB) to each other’s measured from analyzed in two technical replicates computing the abundances with the MaxLFQ software tool. The analytes were…
Khader Y, Al-Rahamneh MJ, Abu Khudair S, Abaza H, Al Shatnawi A, et al.
Objectives Evaluate and determine the gaps in the National Tuberculosis Program and Tuberculosis Surveillance System in Jordan. Methods A concurrent embedded mixed quantitative/qualitative methods study was conducted to assess the National Tuberculosis Program and Tuberculosis Su…
Bhargava A, Bhargava M, Meher A, Benedetti A, Velayutham B, et al.
Background In India, tuberculosis and undernutrition are syndemics with a high burden of tuberculosis coexisting with a high burden of undernutrition in patients and in the population. The aim of this study was to determine the effect of nutritional supplementation on tuberculosi…
V. S. Krutko, L. H. Nikolaieva, Tetiana Maistat, О.A. Oparin, Anton Rohozhyn
Tuberculosis is infectious and socially dependent disease, being now one of the most pressing issues in practical health care. As well the usual types of tuberculosis infection, chemoresistant tuberculosis is spreading rapidly in the world. The WHO estimates that about 500,000 pe…
A.R. Aroyan, А. В. Мордык
Introduction . Extrapulmonary tuberculosis is more difficult to diagnose than respiratory tuberculosis. However, late detection leads to disabling consequences. Children from 4 to 11 years old are at risk for tuberculosis due to increased communication skills. It seems relevant t…
O.I. Sakhelashvili–Bil
Objective — to study the features of multidrug-resistant tuberculosis of the lungs of respiratory organs in children and adolescents from focuses of chemoresistant tuberculosis infection. 
 Materials and methods. To study the features of the course of multidrug-resistant pul…
Ahmad al Jbawi, Mohammad Fadel, Fares Kahal, Michel Najjar, Sara Albuaini, et al.
Abstract Background : Tuberculosis (TB) is a major public health concern worldwide and is the 13th leading cause of death and the second deadliest infectious disease after COVID-19. ¹ Extrapulmonary tuberculosis (EPTB) cases accounted for 16% of the 7.5 million cases of TB worldw…
Prabha Desikan, Aseem Rangnekar, Nikita Panwalkar, Ram Prakash Punde, Sridhar Anand
…etection and treatment of drug resistance in extrapulmonary tuberculosis (EPTB) is a major challenge worldwide. Drug resistance in EPTB has not been studied extensively. However, patients with drug-resistant EPTB have been reported to have poor outcomes[1]. Rifampicin and isoniaz…
Zifodya JS, Kreniske JS, Schiller I, Kohli M, Dendukuri N, et al.
…on (WHO)-recommended rapid tests that simultaneously detect tuberculosis and rifampicin resistance in people with signs and symptoms of tuberculosis. This review builds on our recent extensive Cochrane Review of Xpert MTB/RIF accuracy. Objectives To compare the diagnostic accurac…
Van Hoving DJ, Griesel R, Meintjes G, Takwoingi Y, Maartens G, et al.
Background Accurate diagnosis of tuberculosis in people living with HIV is difficult. HIV-positive individuals have higher rates of extrapulmonary tuberculosis and the diagnosis of tuberculosis is often limited to imaging results. Ultrasound is such an imaging test that is widely…
Ravindra Y Mandolikar, Raju Hanumant Patil, Narendra Madhekar
Introduction: Tuberculosis is a chronic, communicable, infectious disease caused by Mycobacterium tuberculosis bacilli usually affecting lungs primarily resulting in pulmonary tuberculosis. Objective: to evaluate the Revised National Tuberculosis Control Programme (RNTCP) through…
Simon C Mendelsohn, Humphrey Mulenga, Michele Tameris, Tumelo Moloantoa, Stephanus T Malherbe, et al.
**BACKGROUND:** More than half of tuberculosis cases detected by community prevalence surveys are classified as asymptomatic. We evaluated yield of symptom and chest radiograph screening of tuberculosis-exposed household contacts in South Africa. **METHODS:** For this prospectiv…
Melike Hazal Can, Sedona Sweeney, Brian W Allwood, Susan E Dorman, Ted Cohen, et al.
**BACKGROUND:** Untreated pulmonary tuberculosis causes ongoing lung damage, which can persist after treatment. Conventional modelling approaches for assessing tuberculosis health effects might not fully capture these mechanisms. We evaluated how tuberculosis-associated lung dama…