Showing 26–50 of 200 documents
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Chang CJ, Huang JR, Tseng YH, Pan SW, Feng JY, et al.
… of circulating cell-free DNA (cfDNA) differentiates active tuberculosis (TB) from latent TB infection (LTBI). Methods Patients with pulmonary TB, contacts with LTBI, and healthy controls were enrolled (2018-2021). Plasma cfDNA was extracted, and using a 5-methylcytosine (5mC) DN…
Woodruff R, Pratt R, Kolasa M
Problem/condition Elimination of tuberculosis (TB) is defined as reducing TB disease incidence in the United States to less than 1 case per million persons per year. In 2022, TB incidence in the United States was 2.5 TB cases per 100,000 persons. CDC's TB program developed a set …
Sharma N, Bakshi R, Basu S, Zode M, Arora R, et al.
…nitiation, implementation and treatment completion rates of tuberculosis (TB) preventive therapy (TPT) using 3HP (INH-Rifapentine) among household contacts of microbiologically confirmed drug sensitive TB cases on anti-tubercular treatment under programmatic real-world settings. …
Massi MN, Hidayah N, Handayani I, Iskandar IW, Djannah F, et al.
…ificance as an immunomarker for several diseases, including tuberculosis. This study aimed to determine the difference between miR-425-5p and miR-4523 expressions in patients with active pulmonary TB (PTB), latent TB infection (LTBI), and lymph node TB (LNTB), whose diagnosis rem…
Nababan B, Triasih R, Chan G, Dwihardiani B, Hidayat A, et al.
In Indonesia, the implementation of tuberculosis (TB) contact investigation is limited, with low detection rates. We report the yield of and risk factors for TB disease and infection for household contacts (HHCs) investigated using chest X-ray (CXR) screening. We identified HHCs …
Plans-Rubió P, Godoy S, Toledo D, Domínguez A, Caylà J, et al.
…dy was to identify factors associated with non-adherence to tuberculosis (TB) preventive treatment among contacts with latent TB infection for new cases of pulmonary TB cases reported in Catalonia in 2019-2021. All contacts aged 18 years or older with a latent TB infection who re…
Lynn Sosa, Gibril J. Njie, Mark N. Lobato, Sapna Bamrah Morris, William G. Buchta, et al.
…dated recommendations for screening health care workers for tuberculosis, including eliminating serial screening in the absence of exposure or ongoing transmission. This article presents updated recommendations for screening health care workers for tuberculosis, including elimina…
Delia Goletti, Seif Al-Abri, Giovanni Battista Migliori, Cecilia S. Lindestam Arlehamn, Pranabashis Haldar, et al.
Every year, World Tuberculosis (TB) Day is commemorated on March 24 and is targeted at raising public and political awareness of TB, a preventable and treatable disease. World TB Day commemorates the day in 1882 when Professor Robert Koch announced his discovery of the microbial …
Michael Lauzardo, Meghan Nodurft-Froman
Until recently, tuberculosis in children has received little attention from the international public health community, despite it being a key sentinel event indicating recent transmission and hence a window into efforts to control transmission.1Shingadia D Novelli V Diagnosis and…
MV Smilianska, AY Volianskyi, LA Sukhanova, NV Kashpur
…ades, great changes have taken place in the epidemiology of tuberculosis (TB), which are reflected in the change in the statistical indicators of the spread of tuberculosis, due to both the infectious and social nature of the disease. At the end of the 20th century, after a long …
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 3: Supplemental database 3. Global ANOVA analysis to identify the proteins that showed significant differences among the eight groups (HC, LTBI, NTM, and TB) in plasma samples with and without stimulation. To perform the quantization analysis, the LFQ values of ea…
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 4: Supplemental dataset S4. Independent-sample t-tests to identify proteins that were up-regulated or down-regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail. Fifty-nine proteins were significantly regulated upon stimulation with the ESAT-6/CFP-10 …
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 2: Supplemental dataset S2. Differentially abundance values of proteins comparing four groups (HC, LTBI, NTM and active TB) to each other’s measured from analyzed in two technical replicates computing the abundances with the MaxLFQ software tool. The analytes were…
Berrocal-Almanza LC, Harris R, Lalor MK, Muzyamba MC, Were J, et al.
… Evaluating interventions that might lead to a reduction in tuberculosis in high-income countries with a low incidence of the disease is key to accelerate progress towards its elimination. In such countries, migrants are known to contribute a large proportion of tuberculosis case…
Kim JW, Bowman K, Nazareth J, Lee J, Woltmann G, et al.
Background Incipient tuberculosis, a progressive state of Mycobacterium tuberculosis infection with an increased risk of developing into tuberculosis disease, remains poorly characterised. Animal models suggest an association of progressive infection with bacteraemia. Circulating…
Belay M, Tulu B, Younis S, Jolliffe DA, Tayachew D, et al.
…rface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent tuberculosis infection. Our aim was to determine whether M tuberculosis complex DNA is detectable in CD34-positive peripheral blood mononuclear cells (PBMCs) isolated from asymp…
E. M. Bogorodskaya, E. M. Belilovsky, L. B. Ayusheeva, E. N. Posadskaya
…tients with HIV infection is of the leading risk groups for tuberculosis. According to WHO, the presence of HIV infection increases the likelihood of developing tuberculosis by 26 times and is the second factor in the world after malnutrition that affects the number of cases of t…
Yang C, Yasseen AS 3rd, Stimec J, Rea E, Waters V, et al.
…ground There are few data about the utility of the Canadian tuberculosis medical surveillance system for detecting tuberculosis in children and adolescents. We sought to assess the prevalence of tuberculosis infection and disease in children and adolescents referred by the tuberc…
Yue Yu, Qiao Yu, Ke Ren Shen, Ding Ting Xu, Wen Hu, et al.
The datasets during the current study are available from the corresponding author upon reasonable request.
G. S. Oganezova, E. M. Bogorodskaya, N. I. Briko, E. M. Belilovsky
…ection not only through the identification of patients with tuberculosis, but also through the identification of patients infected with M. tuberculosis, who still do not have manifestations of a local form of the disease. This made it possible to search for persons who were infec…
Saha A, Escuduero J, Layouni T, Richardson B, Hou S, et al.
…ound Pregnancy is a risk factor for progression from latent tuberculosis infection to symptomatic tuberculosis. However, how pregnancy influences T-cell responses to Mycobacterium tuberculosis is unknown. Methods We measured M. tuberculosis-specific cytokines, T-cell memory marke…
Barham MS, Whatney WE, Khayumbi J, Ongalo J, Sasser LE, et al.
…ficant risk factor for reactivation of latent Mycobacterium tuberculosis infection (LTBI) and progression to active tuberculosis disease, yet the mechanisms whereby HIV impairs T cell immunity to M. tuberculosis have not been fully defined. Evaluation of M. tuberculosis -specific…
Rebecca Berhanu, Karen R. Jacobson
EditorialsOctober 2021Tuberculosis Preventive Therapy for People With HIV Infection in High Tuberculosis Burden Settings: How Much Is Enough?Rebecca H. Berhanu, MD and Karen R. Jacobson, MD, MPHRebecca H. Berhanu, MDBoston University School of Public Health, Boston, Massachusetts…
Harirzadeh S, Kazemi MJ, Babakhani S
Introduction: Mycobacterium tuberculosis is the cause of pulmonary and extra-pulmonary tuberculosis. Latent tuberculosis is asymptomatic and the results of mycobacterial culture in this case are negative. The purpose of this study was to determine the prevalence of M. tuberculosi…
Cheng Chen, Leonardo Martínez, Biao Xu
…fth of the world population was infected with Mycobacterium tuberculosis (1)，and about 10% of the infected population will finally progress to tuberculosis (TB) disease. The risk of progressing to TB disease was significantly high in the first 2 years of infection (2). However, c…