Global tuberculosis report 2021

Tuberculosis remains a major global public health challenge and a leading cause of death from a single infectious agent, closely associated with poverty, undernutrition, HIV infection and other social determinants. This annual report, part of a series produced by the World Health Organization since 1997, presents a comprehensive and up-to-date assessment of the global tuberculosis epidemic and the response to it at global, regional and national levels, in the context of the Sustainable Development Goals, the End TB Strategy and commitments made at the United Nations high-level meeting on tuberculosis.

Drawing on data reported by 197 countries and territories representing over 99% of the global population and TB cases, it examines trends in incidence, mortality and drug-resistant tuberculosis, as well as progress towards global targets. The 2021 edition adopts a concise format centred on main findings and messages, complemented by expanded web-based content. The report outlines key components of the response, including diagnosis and treatment, prevention, financing, universal health coverage and determinants, and research and innovation. Particular attention is given to the impact of the COVID-19 pandemic, which has disrupted essential services, reduced case detection and led to increases in tuberculosis deaths after years of decline. Intended for policymakers, programme managers and stakeholders, it highlights persistent gaps in access to care and funding, and underscores the urgency of strengthened multisectoral action and increased investment to restore progress and accelerate efforts to end the tuberculosis epidemic.