Showing 1–25 of 200 documents
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Mohau S. Makatsa
… of the treatment is hampered by multidrug resistant TB and HIV infection. There is an urgent need for an effective TB vaccine to prevent ongoing transmission. The development of a new and efficacious TB vaccine will likely be dependent on our understanding of protective immunity…
John C. Mgogwe, Jaffu Otheniel Chilongola
…nt tuberculosis (MDR-TB) with human immunodeficiency virus (HIV) immunologic state which is marked by chemokine and cytokine distortion is indicated by boosting the defense stimulation to a patient. The effect of coexisting infections on the MDR-TB patient with HIV is still not f…
Elizabeth Corbett, MD, David Dowdy, MD. PhD, Lawrence Moulton, PhD
… algorithms for TB case detection on Tuberculosis (TB)- and HIV-related outcomes; (2) to compare the impact of using the routine screening and GeneXpert algorithms for exclusion of TB prior to initiation of IPT and ART on TB- and HIV-related outcomes; and (3) to assess the relati…
Lusiana R Idrus, Master
…tionale: The co-infection of human immunodeficiency virus (HIV) and tuberculosis (TB) diseases presents further problems to patient's adherence due to high pill burden and adverse effects in the drug combination therapy. This situation is also a risk of the increase of multi-dru…
John C. Mgogwe, Balthazar Nyombi, Oliva S. Massay, Hadija Semvua, Jaffu Chilongola
…lti Drug Resistant Tuberculosis TB (MDR-TB) with or without HIV infection, undergoing treatment with second-line Anti TB plus ARV’s or second-line anti TB. Objective To assess the hematological, biochemical and immunological indices of patients with or without HIV-MDR-TB at the K…
Marimani M, Ahmad A, Stacey S, Duse A
…rate groups including healthy, multidrug-resistant (MDR) TB-HIV co-infected and HIV-1 positive individuals. Methods Ten patients with MDR TB and HIV-1 co-infection on TB and HIV therapy and a cohort comprised of 10 newly diagnosed individuals with HIV-1 infection were recruited f…
Indana Eva Ajmala, Laksmi Wulandari
TB and HIV have a very close relationship since the development of AIDS. Through a significant reduction in cellular immunity, HIV affects the pathogenesis of tuberculosis, thereby increasing the risk of TB in HIV co-infected individuals. In 2006, there were an estimated 9.2 mill…
Anthony Garcia-Prats, MD, Ethel Weld, MD
…imen (OBR) for multidrug-resistant tuberculosis (MDR-TB) in HIV-infected and HIV-uninfected children with MDR-TB. The purpose of this study is to evaluate the pharmacokinetics, safety, and tolerability of the anti-TB drug DLM in combination with OBR for MDR-TB in HIV-infected an…
Frolova Op, T. I. Sharkova, O. V. Butylchenko, Л. П. Северова, A. V. Abramchenko
…e Russian Federation in 2021, human immunodeficiency virus (HIV) infection was more often registered in the general population than in vulnerable groups. AIMS: This study aimed to determine the characteristic patient cohorts with tuberculosis (TB) and HIV coinfection in dynamic e…
Sianturi EI, Izzah Z, Huda K, Sada EM, Perwitasari DA, et al.
Introduction human immunodeficiency virus (HIV) and tuberculosis (TB) remain global health problems and impose a substantial reduction in people´s quality of life (QoL). This study aimed to assess and compare the QoL in HIV and TB patients and factors associated with QoL between …
Huma Haider
…ica with a population of approximately 15 million. Malaria, HIV and tuberculosis (TB) remain important public health concerns in the country, despite significant progress over the past two decades. Malaria incidence has declined markedly between 2003 and 2019 (by 81% from 2003 to…
Sujit Kumar Bhattacharyya, Pratik Barma, Rajarshi Bhattacharyya
…n increasing association with human immunodeficiency virus (HIV). As multidrug resistant tuberculosis (MDR-TB) is determined by microbiological testing, early detection of MDR -TB by X-Ray chest is highly recommended to help in guiding diagnostic confirmation. The chest x-ray pat…
…s that both multidrug-resistant tuberculosis spread and the HIV epidemic are factors maintaining the high tuberculosis burden worldwide and in the Russian Federation. The main transmission pathway for HIV-infection in the Russian Federation, as well as in other countries of Easte…
Tornheim JA, Dooley KE
…view In the past few years, tuberculosis (TB) has overtaken HIV as the infectious disease with the highest global mortality. Successful management of this syndemic will require improved diagnostic tests, shorter preventive therapies, and more effective treatments, particularly in…
Bentzon AK, Panteleev A, Mitsura V, Borodulina E, Skrahina A, et al.
…distinct discrepancies in delivery of tuberculosis (TB) and HIV services in eastern Europe (EE) vs. western Europe (WE). Objectives To verify the differences in TB and HIV services in EE vs. WE. Methods Twenty-three sites completed a survey in 2018 (EE, 14; WE, nine; 88% response…
Frolova OP, Butylchenko OV, Gadzhieva PG, Timofeeva MY, Basangova VA, et al.
…primary cause of mortality in human immunodeficiency virus (HIV) patients in Russia. Since the beginning of 2000, a sharp change in the HIV patients' structure, to the main known risk factors for HIV infection has taken place in Russia. The transmission of HIV through injectable …
Cruz S. Sebastião, João Samulengo, Joana Pauxão, António Mateus, Zinga David, et al.
TB and HIV continue to increase and constitute major public health concerns worldwide, mainly in resource-limited countries, showing that we are not going to end HIV if we do not also end TB. Herein, we investigated the risk factors related to HIV infection among TB patients in L…
Laston Gonah, Talent Maphosa
…e investigated association of MDR-TB treatment outcomes and HIV status in Zimbabwe. The study was a retrospective cohort study of case records from National TB Surveillance System of MDR-TB patients (>16 years) who were culture proven at diagnosis and started treatment between Ja…
Bastard M, Sanchez-Padilla E, du Cros P, Khamraev AK, Parpieva N, et al.
…ce of resistance to anti-tuberculosis (DR-TB) drugs and the HIV epidemic represent a serious threat for reducing the global burden of TB. Although data on HIV-negative DR-TB treatment outcomes are well published, few data on DR-TB outcomes among HIV co-infected people is availabl…
Francisco C, Lansang MA, Salvana EM, Leyritana K
Tuberculosis (TB) is common among persons living with HIV. This public health concern is aggravated by infection with multidrug-resistant organisms and adverse effects of polypharmacy. There are few published cases of multidrug-resistant tuberculosis (MDR-TB) in multidrug-resista…
Padayatchi N, Bionghi N, Osman F, Naidu N, Ndjeka N, et al.
…ot been extensively studied among patients co-infected with HIV drug-resistant tuberculosis (DR-TB). We compared treatment outcomes in DR-TB patients treated with BDQ- and linezolid (LZD) containing regimens to historic controls treated with second-line injectable-containing regi…
Kelly Dooley, MD
…with certain antiretroviral (ARV) medications used to treat HIV. People whose immune systems are weakened by HIV infection are susceptible to TB, so it is important to find treatments for both that can be given in combination. This study will test the safety of combining a new me…
Chem ED, Van Hout MC, Hope V
Background Multidrug-resistant tuberculosis (MDR-TB) in HIV endemic settings is a major threat to public health. MDR-TB is a substantial and underreported problem in Sub-Saharan Africa (SSA), with recognised cases projected to increase with advancement in diagnostic technology. T…
Dyan Kunthi Nugrahaeni, Salma Zaqiya
…y of previous TB treatment and increased co-infection of TB-HIV (Human Immunodeficiency Virus). This study aimed to identify the relationship between history of previous TB treatment and HIV status with MDR-TB. This is a case control study. The sample case was patients with MDR-T…
World Health Organization. Regional Office for Europe
…oordinating meeting of the WHO collaborating centres on TB, HIV, viral hepatitis and STI was held on 7 May 2020. Due to the COVID-19 pandemic, the meeting was conducted virtually, allowing all participants to attend the meeting remotely. The overall objectives of the meeting were…