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Xie K, Zhang Y, Zhang M, Wu H, Zheng L, et al.
…e disease. VDD is also associated with an increased risk of HIV-related comorbidities and mortality, and patients have a tendency to develop active tuberculosis compared to those with latent tuberculosis infection. Vitamin D supplementation may modulate HIV replication, improve T…
Helen Ayles, Professor
Tuberculosis (TB) has overtaken HIV as the leading infectious cause of death worldwide and requires a major policy shift for it to be controlled in line with the WHO Stop-TB goal to "end TB". However, how to control TB at population level in the context of HIV, is unknown. Some o…
Surendra K Sharma, M.D., Ph.D
HIV induced altered representation and function of regulatory T cell subsets (NKT and Treg cells) impair the protective T cell response against M.tuberculosis and disrupts LTBI, thus facilitates faster progression and development of severe forms of clinical TB in HIV-TB co-infect…
VINA LUSIANA
…an Immunode_ciency Virus/Acquired Immuno-deciency Syndrome (HIV/AIDS) are major burden of infectious diseases in developing countries. TB and HIV infection have the effect of deeply on assault the immune system, since they can afford to weaken host immune respone through a mechan…
Balfour A, Schutz C, Goliath R, Wilkinson KA, Sayed S, et al.
…l numbers generally decrease in patients with active TB and HIV infection, but findings regarding functional changes differ. Methods: We conducted a cross-sectional study on the effect of HIV, TB, and HIV-associated TB (HIV-TB) on MAIT cell frequencies, activation and functional …
Vannesa Yue May Teng, Yan Ting Chua, Eunice En Ni Lai, Shilpa Mukherjee, Jessica Michaels, et al.
…TRACT Objectives Tuberculosis (TB) is a common infection in HIV patients. Our study aims to determine the prevalence and characteristics of HIV-TB co-infected patients in Singapore, a high-income, intermediate TB-burden country. Methods Retrospective data of 11-years was obtained…
Teng VYM, Chua YT, Lai EEN, Mukherjee S, Michaels J, et al.
Objectives To examine the prevalence and characteristics of HIV-tuberculosis (TB) co-infected patients in Singapore, an intermediate TB-burden country. Methods Retrospective data across 11 years was obtained from the National University Hospital (NUH), a quaternary hospital and t…
Linda Gail Bekker, MBChB, FCP, PhD, James McIntyre, MBChB, MRCOG
…e Town, South Africa, a community with high rates of TB and HIV. This study will also examine the genetics of TB and the relationships among active TB infection, new HIV infections, and HIV disease progression. TB is the most common opportunistic infection and the single most co…
Gebremicael G, Alemayehu M, Sileshi M, Geto Z, Gebreegziabxier A, et al.
…s with five clinical groups: 57 TB patients coinfected with HIV (HIV+TB+), 87 active TB Patients (TB cases), 71 HIV infected without active and latent TB infection (HIV+TST-), 22 latent TB infection (TST+) and 25 healthy controls (TST-). Vitamin A concentration was measured using…
Winter JR, Stagg HR, Smith CJ, Lalor MK, Davidson JA, et al.
Background HIV increases the progression of latent tuberculosis (TB) infection to active disease and contributed to increased TB in the UK until 2004. We describe temporal trends in HIV infection amongst patients with TB and identify factors associated with HIV infection. Methods…
de Vries G, van de Berg S, van Dam A, Hasanova S, Pareek M, et al.
…ated 12% of tuberculosis (TB) patients are co-infected with HIV in the World Health Organization European Region (the Region). Reducing morbidity and mortality from HIV-associated TB requires strong collaboration between TB and HIV services at all levels with integrated people-ce…
Yuyun Monita, Putroue Keumala Intan
The condition in which an individual is affected by TB and HIV/AIDS in his body is called a TB-HIV/AIDS coinfection. This research aims to minimize the populations of TB-HIV/AIDS coinfection with a minimum expenditure on medical expenses, that means minimizing the objective’s fun…
Habibi P, Daniell H, Soccol CR, Grossi-de-Sa MF
Tuberculosis (TB) and human immunodeficiency virus (HIV) can place a major burden on healthcare systems and constitute the main challenges of diagnostic and therapeutic programmes. Infection with HIV is the most common cause of Mycobacterium tuberculosis (Mtb), which can accelera…
Ihim Augustine Chinedu, Meludu Samuel Chukwuemeka, Onyenekwe Charles Chinedum
…ting 120 treatment naive individuals with active TB [26 (TB+HIV+) and 12 malaria parasite (MP) and TB (TB+MP+) co-infection, 82 HIV negative (TB+HIV−)], 26 Latent TB (LTB) and 105 apparently healthy control (AHC). TB infection was determined by Ziehl-Neelsen sputum smeared micros…
Daniel Bonnet, MD, France Mentre, PHD
… and T-SPOT.TB® for the diagnosis of latent tuberculosis in HIV infected antiretroviral naive patients: 80 originated from low TB prevalence countries, without any active TB; 80 HIV infected antiretroviral naïve patients originated from high TB prevalence countries, without any a…
S. T. Kavya, Avinash Hanbe Rajanna, Pradeep R. Bojja
HIV-TB Co-infection is increasing in the current scenario. TB is the leading cause of mortality in people living with HIV (PLHIV). HIV-infected persons have approximately an 8-times greater risk of TB than persons without HIV infection. HIV infection increases the risk of reactiv…
Irini Sereti, M.D.
…ho are also infected with the human immunodeficiency virus (HIV). However, not much is known about how these two infections affect each other. Some people who have HIV or TB infections develop health problems after they start taking either HIV or TB medications or both. These dru…
Rewari BB, Kumar A, Mandal PP, Puri AK
Introduction : HIV and tuberculosis (TB) are two of the most challenging infections faced by humanity and place immense burden on health care systems worldwide. Both HIV and TB impact one another's progression. Areas covered : HIV is the most important risk factor for progression…
Liu Q, Yu C, Cheng J, Jiang Y, Xu Y, et al.
…cells, but also highly expressed on the T cells membrane in HIV-1 negative patients with tuberculosis (TB). However, the study on membrane-bound IL-22+ cells of HIV-1 infected patients is rare. Therefore, we investigated antigen-specific membrane-bound IL-22+ T cell subsets in My…
Riti Sharan, Yi Zou, Bindu Singh, Vinay Shivanna, Edward J Dick, et al.
Most HIV-negative individuals exposed to Mycobacterium tuberculosis (Mtb) control infection as latent TB infection (LTBI), but HIV co-infection greatly increases progression to tuberculosis (TB), the leading cause of death in people living with HIV (PLHIV). Although combination a…
Catherine Keiko Gunawan, Anton Sumarpo, Agnes Rengga Indrati
…ysregulation is a hallmark of human immunodeficiency virus (HIV) infection, characterized by persistent immune activation and systemic inflammation that drive T cell exhaustion and senescence, contributing to disease progression and non-AIDS comorbidities, most notably tuberculos…
Semá Baltazar C, DeLima YV, Ricardo H, Botão C, Chitsondzo Langa D, et al.
…d As part of ongoing efforts to generate evidence needed on HIV and tuberculosis (TB) to inform policies and programs aimed to improve the health outcomes of migrants and communities affected by migration and mining, a preliminary investigation was conducted through a biological …
…etrics Abstract While tuberculosis (TB) is a risk factor in HIV-1-infected individuals, the mechanisms by which Mycobacterium tuberculosis (Mtb) worsens HIV-1 pathogenesis remain scarce. We showed that HIV-1 infection is exacerbated in macrophages exposed to TB-associated microen…
Maeva Dupont, Shanti Souriant, Luciana Balboa, Thien‐Phong Vu Manh, Karine Pingris, et al.
…etrics Abstract While tuberculosis (TB) is a risk factor in HIV-1-infected individuals, the mechanisms by which Mycobacterium tuberculosis (Mtb) worsens HIV-1 pathogenesis remain scarce. We showed that HIV-1 infection is exacerbated in macrophages exposed to TB-associated microen…
Mangochi P, Bossard C, Catacutan C, Van Laeken D, Kwitonda C, et al.
BACKGROUND Incarcerated individuals, especially in high HIV and TB burden settings, are at increased risk of latent TB infection and/or TB disease. We implemented a comprehensive HIV-TB intervention in a Malawi prison and studied its feasibility. METHODS Between February and Dece…