Showing 1–14 of 14 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Tatiana Minogina, Leonid Lavrenchuk, Diana Vakhrusheva, Sergey Skornyakov
… Mycobacterium tuberculosis (Mtb) in bone tissue. Molecular diagnostics have improved pathogen detection; however, cases with concomitant HIV andHCV infections remain problematic. These conditions, marked by immunosuppression, systemic inflammation, endothelial dysfunction and al…
Katran ZY, Bulut İ, Babalık A, Keren M, Tepetam FM, et al.
Objective To evaluate drug resıstant tuberculosis patients who developed drug hypersensitivity to antituberculosis drug. Methods This was a retrospective study. The primary aim of the study is to determine the demographic and clinical characteristics of patients who develop drug …
Gupta M, Ish P, Malhotra N
The recent guidelines on the Programmatic Management of Drug-Resistant Tuberculosis (DR-TB) in India (PMDT) have been released in March 2021 on World TB Day. The new guidelines have considered emerging diagnostic trends including TrueNat, Xpert Mtb/XDR, Next generation sequencing…
Saeed DK, Shakoor S, Razzak SA, Hasan Z, Sabzwari SF, et al.
…s required so that they may be incorporated in genome-based diagnostics for drug resistant MTB.
Hameed HMA, Tan Y, Islam MM, Guo L, Chhotaray C, et al.
Background Levofloxacin (LVX) and Moxifloxacin (MXF) are the cornerstones for treatment of multidrug-resistant tuberculosis (MDR-TB). China is one of the highest MDR- and fluoroquinolones (FQ)-resistant TB burdens countries. DNA gyrase encoded by gyr genes is the main target of F…
Divya Bhatt, Rashmi Ratnam, Faisal Abbas, Manu Singh, Urmila Singh, et al.
**BACKGROUND:** Ageing affects the clinical presentation of diseases due to associated comorbidities, often leading to diagnostic imprecision and specialized treatment needs in healthcare systems that are not well-equipped to address such challenges. Robust data analysis of geria…
Ghosh A, Biswas VK, Bal HB, Das D, Pati S, et al.
Whole genome sequencing has been used to investigate the genomic diversity of M. tuberculosis in the northern and southern states of India, but information about the eastern part of the country is still limited. Through a sequencing-based strategy, this study seeks to comprehend …
Alexandra Isakova, Yu. D. Mikhailova, M. A. Sviridenko, Anastasia Khakhalina, Ksenia Galkina, et al.
The paper presents data on testing the drug susceptibility of clinical isolates of M. tuberculosis (MTB) to fluoroquinolones and injectable drugs using molecular genetic tests and phenotypic methods. We demonstrated the diagnostic capabilities of the hybridization technologies «T…
Piamlarp Sangsayunh, Thanyanuch Sanchat, Charoen Chuchottaworn, Krisana Cheewakul, Sirijit Rattanawai
The primary objective of this study was to evaluate the real-world effectiveness, side effects and challenges associated with the implementing of the groundbreaking BPaL-containing regimen in Thailand. Another aim was to investigate the characteristics and severity of the disease…
Marie José Bajani Kabedi, Steve Ahuka, Octavie Metila Lunguya, Jean Marie Kayembe, Hippolyte Nani Tuma Situakibanza, et al.
Context and objective : In endemic regions such as the Democratic Republic of the Congo, children are likely to be exposed to tuberculosis (TB) through close contact. Failure to diagnose can have devastating consequences. The objective of the present study was to determine the fr…
R Santosh
Introduction: Drug-resistant tuberculosis is a major public health problem throughout world. India accounts for 27% of global TB burden. More than half of TB patients in India are cared for in private sector. Usage of inappropriate TB diagnostic, treatment practices and lack of a…
O. A. Zhurilo, А. І. Barbova, L.B. Skokluk, O. V. Chernov
…ociated with a high level of resistance. Key words: genetic diagnostics, sequencing, pulmonary tuberculosis.
…regular reports, while the quality of local microbiological diagnostics on is insufficient
Pinhata JMW, Brandao AP, Gallo JF, Oliveira RS, Ferrazoli L
We assessed the performance of MTBDRsl for detection of resistance to fluoroquinolones, aminoglycosides/cyclic peptides, and ethambutol compared to BACTEC MGIT 960 by subjecting simultaneously to both tests 385 phenotypically multidrug-resistant-Mycobacterium tuberculosis isolate…