Showing 1–7 of 7 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Krishnakumariamma K, Ellappan K, Muthuraj M, Tamilarasu K, Kumar SV, et al.
…c health concern worldwide. We evaluated the performance of GeneXpert MTB/RIF (GeneXpert) for the diagnosis of TBM. In addition, genetic diversity and drug susceptibility profiling of Mtb strains isolated from TBM patients were also investigated. A total of 293 TBM suspected cere…
National Heart and Lung Institute
…quencing (WGS) on positive Mycobacterium tuberculosis (MTb) culture samples. Given the lack of research and large global ASM workforce, 1 million of whom are in Tanzania, the results of this study will assist in the development and introduction of interventions to reduce the ris…
Raunak Bir, Urvashi B Singh, Hitender Gautam, Nishant Verma, Kiran Bala, et al.
…entional diagnostic methods, such as smear microscopy, lack sensitivity and timeliness. This study evaluates the prognostic value of time to positivity (TTP) from liquid culture and cycle threshold (CT) values from GeneXpert/rifampicin (Cepheid, Sunnyvale, CA) in predicting treat…
Ebrahim Variava, Tumelo Moloantoa, Neil Martinson
…a remarkable leap forward for tuberculosis diagnostics. The GeneXpert tuberculosis assay (Cepheid, Sunnyvale, CA, USA) provides a result in 2 h, is both highly sensitive and specific, and is a major improvement over conventional smear microscopy. Moreover, simultaneous testing fo…
Bahizi G, Majwala RK, Kisaka S, Nyombi A, Musisi K, et al.
…istance), presents challenges to TB control. In Uganda, the GeneXpert test provides point-of-care testing for TB and rifampicin resistance. Patients identified with RR-TB receive culture-based drug susceptibility testing (DST) to identify additional resistance, if any. There are …
Emelia Konadu Danso, Prince Asare, Amanda Yaa Tetteh, Phillip Tetteh, Augustine Asare Boadu, et al.
…nt outcomes. We conducted a prospective cohort study of 758 GeneXpert-confirmed pulmonary TB patients, of whom 75 had DM. Demographic, clinical, radiographic, and anthropometric data were collected at baseline. Sputum samples were cultured for mycobacterial isolation, and the obt…
Ershova JV, Volchenkov GV, Somova TR, Kuznetsova TA, Kaunetis NV, et al.
Background The main advantage of GeneXpert MTB/RIF® (Xpert) molecular diagnostic technology is the rapid detection of M.tuberculosis DNA and mutations associated with rifampicin (RIF) resistance for timely initiation of appropriate treatment and, consequently, preventing further …