Showing 1–11 of 11 documents
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Gao M, Wu Q, Wang X, Sun X, Li M, et al.
…73 cases of PTB and 42 cases of EPTB. Sputum smears, sputum culture, TB-RNA, GeneXpert, and urine LAM results were obtained from all patients before treatment. Using the composite reference standard as the reference, the diagnostic performance of these methods for PTB and EPTB wa…
Rushna Wazahat, Mehvash Haider, Debasish Chattopadhya, Mridu Dudeja
…ected to staining (Ziehl-Neelson and fluorescent staining), culture, GeneXpert, and line probe assay. Results: The sensitivity, specificity, and strength of association, i.e., kappa (k) value of LED-FM, ZN, and GeneXpert, were calculated using standard formulae using solid cultur…
Chen P, Sun W, He Y
…ds In this study, we collected the results of both mNGS and culture of 70 specimens from suspected TB patients at the Shanghai Pulmonary Hospital of Tongji University. Results of GeneXpert MTB/RIF assay (Xpert) were obtained from 19 patients. We also assessed the diagnostic perfo…
Tummidi Santosh, Prashant Sood, Ashok Rattan, Deepa Dave, Puneeta Nagiredla
…assessed the diagnostic and quantitative performance of the GeneXpert Mycobacterium tuberculosis/resistance to rifampicin (MTB/RIF) assay on pulmonary and extrapulmonary samples processed in an Indian laboratory. We examined this to assess if GeneXpert can complement existing dia…
Xu JC, Shi X, Ma X, Gu WF, Fang ZX, et al.
… (OR 2.22, 95% CI 1.17-4.28, p = 0.014). In biopsy samples, GeneXpert (Xpert) showed higher sensitivity (96.6% [91.6-98.7], p 95%) and specificity (nearly 100%) of any methods. In non-biopsy samples, only T-SPOT. TB (T-SPOT) showed higher sensitivity than culture (90.9% [62.3-99.…
Mukesh Rathod, Abdul Qavi, Vineeta Mittal, Ajai Kumar Singh, Pradeep Kumar Maurya, et al.
…he smear testing of the cerebrospinal fluid (CSF) has a low sensitivity and cultures, though having higher sensitivity, take a long time in TBM diagnosis. The present study was done to evaluate the proportion of positive Gene Xpert test, a rapid nucleic acid amplification test, i…
Ferroudja Yamouni, Fatma Zohra Henniche, Malika Ifticene, Madjid Chabani, Doria Bensersa, et al.
…s of pulmonary and extra-pulmonary tuberculosis compared to culture. 2) To compare the rifampicin results resistance obtained by GX with the phenotypic sensitivity test. Materials and methods: Retrospective study carried out over a period of five years, from May 2017 to June 2022…
Grønningen E, Nanyaro M, Sviland L, Ngadaya E, Muller W, et al.
…istry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests in the resource limited diagnostic setting. The aim of this study was to validate the implementability and diagnostic performance of the test in PLWHIV and HIV negative ad…
Aarhus University Hospital
…m sampling (faecal and a buccal/tongue swab and saliva) for GeneXpert Ultra PCR (Xpert) as state-of-the-art add-ons to the routine diagnostic pathway for TB. This adds to the key components of the WHO "End TB" strategy - early diagnosis - and if successful, may be rapidly approve…
Hoa NB, Fajans M, Nguyen Van H, Vu Ngoc B, Nguyen Viet N, et al.
…ompared to a microbiological reference standard (MRS) using GeneXpert Ultra and TB culture testing. Estimated uLAM concentrations above plate specific calculated limit of detection (LOD) were considered uLAM positive. Additional microbiological testing was conducted for possible …
Grønningen E, Nanyaro M, Sviland L, Ngadaya E, Muller W, et al.
…istry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study was to implement and validate the test performance in a resource limited African setting. Presumptive pediatric (0-18 y) EPTB patients were prospect…