Showing 1–6 of 6 documents
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Helen McShane
…d HIV present major new challenges. The currently available vaccine, M. bovis BCG, is largely ineffective at protecting against adult pulmonary disease in endemic areas and it is widely agreed that a new more effective tuberculosis vaccine is a major global public health priority…
Aishwarya Venkataraman, MRCPCH
Bacille Calmette Guerin (BCG) vaccine is one of the most used vaccines of the world, to reduce the risks of natural tuberculous infection. The efficacy of BCG vaccination in newborns is well known and has a documented protective effect against meningitis and disseminated TB in ch…
Gregor Nosan, Andreja Cerkvenik Škafar
…coring the continued role of Bacillus Calmette-Guérin (BCG) vaccination. BCG vaccination provides strong protection against severe forms of TB in infancy, though its efficacy against pulmonary disease in adolescents and adults is modest. However, the BCG vaccine carries a ri…
Penny M. Heaton, Jeffrey S. Barrett
…scribes some of the institute's work on candidate drugs and vaccines against tuberculosis, the leading infectious diseases killer in the world. The Bill & Melinda Gates Medical Research Institute (Gates MRI) is a nonprofit biotechnology organization focused on diseases that dispr…
Ferdous Ara Ahmed, Beatrice Onyinyechi Mkpa, Sadia Afroz, M. Naimul Islam Nakib, Md Nabiul Islam
… aims to investigate the trends of TB prevalence, treatment efficacy, and prevention efforts in a cohort of 300 TB cases in Dhaka. Methods: A cross-sectional study design was utilized to assess TB prevalence, treatment outcomes, and prevention efforts among 300 TB cases in Dhaka.…
…tions conducted a randomized controlled trial to assess the efficacy and safety of levofloxacin in preventing tuberculosis (TB) in children who were household contacts of an adult with multiple drug resistant (MDR) TB. The study was conducted at 5 sites in South Africa between 20…