Showing 176–200 of 200 documents
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Epicentre
…m samples from adult pulmonary TB suspects in a high TB and HIV prevalence setting, using LJ and MGIT culture as gold standard. The Secondary objectives are: * To measure the performance of each assay (NRA, NRA-p, REMA-p) in sputum smear-negative patients * To describe the resu…
Human Sciences Research Council
…d South Africa has high burdens of tuberculosis (TB) and TB-HIV, yet the quality of patient care in the private sector is unknown. We describe quality of TB and TB-HIV care among private general practitioners (GPs) in two South African cities using standardised patients (SPs). Me…
Dian Natasya Rahardjo, Stefannie Sherine Santoso, Retnosari Andrajati, Ratu Ayu Dewi Sartika, Mariana Wahjudi
…roduction: Indonesia is one of the countries with a high TB-HIV prevalence. Antiretroviral treatment (ART) is only being administered to approximately 42% of TB-HIV patients. The low utilization of ART can be attributed, in part, to the delayed initiation of treatment. Nonetheles…
Hamada Y, Getahun H, Tadesse BT, Ford N
…g cause of morbidity and mortality among people living with HIV. HIV-associated TB disproportionally affects African countries, particularly vulnerable groups at risk for both TB and HIV. Currently available TB diagnostics perform poorly in people living with HIV; however, new di…
Puspita Kristina Kusumawati, Lintang Dian Saraswati, Martini Martini, Retno Hestiningsih
HIV and Tuberculosis are two public health problems of global concern. People living with HIV (PLWH), can develop opportunistic infections because they do not know their HIV status. With the vulnerability of PLWH to opportunistic infections, especially TB, it is necessary to rout…
Kaplan R, Hermans S, Caldwell J, Jennings K, Bekker LG, et al.
…d over the last decade with an estimated coverage of 63% of HIV- positive patients in 2013. The influence of ART on the characteristics of the population of HIV-positive patients presenting to the primary care TB programme is unknown. In this study, we examined trends in CD4 coun…
Kushwaha S, Yadav R, Kumar R, Kumar S, Chauhan DS, et al.
…erum exosomal microRNAs in Indian patients with and without HIV-TB coinfection. Methods The pool samples of serum exosomes of study participants (HIV-TB coinfection, extra-pulmonary TB, HIV mono-infection, pulmonary TB) and healthy humans were processed for the isolation of total…
Kagujje M, Somwe P, Hatwiinda S, Bwalya J, Zgambo T, et al.
…ective To determine the prevalence of tuberculosis (TB) and HIV in 13 Zambian correctional facilities. Methods Cross-sectional study. Setting 13 correctional facilities in seven of the 10 provinces in Zambia. Participants All incarcerated individuals were eligible for TB and HIV …
Amelia Stanton, PhD
…IT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among individuals with HIV and/or TB in Cape Town, South Africa. If feasibility, acceptability, and preliminary efficacy are demonstrated, the intervention will be ready for large-scale effectiv…
Nisreen Khambati, Kattya Lopez Tamara, Elizabeth Nakabugo, Arthur Van Valkenburg, Jessica K Anderson, et al.
…gnosis of pulmonary tuberculosis (TB) in people living with HIV remains difficult. Since the first pathogen-host interaction in TB occurs in the upper airway, we hypothesized that host transcriptomic analysis on nasal specimens may identify novel diagnostic biomarkers. We aimed t…
Uzochukwu Godswill Ekeleme, Ikenna Oluebube Ogini, Stanley Chinedu Eneh, Ugonma Winnie Dozie, Stephanie Adiruo Akunna, et al.
Nearly 90% of children living with HIV and tuberculosis are domiciled in Sub-Saharan Africa. Given the paucity of data on TB-HIV co-infection in children, this study aimed to understand the factors associated with co-infection in children receiving antiretroviral therapy (ART) in…
Moodley P, Martinson NA, Joyimbana W, Otwombe KN, Abraham P, et al.
Background HIV and tuberculosis (TB) independently cause an increased risk for venous thromboembolic disease (VTE): deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Data from high HIV and TB burden settings describing VTE are scarce. The Wells' DVT and PE scores are wid…
Broset E, Saubi N, Guitart N, Aguilo N, Uranga S, et al.
…in). With the aim of using MTBVAC as a vector for a dual TB-HIV vaccine, we constructed the recombinant MTBVAC.HIVA 2auxo strain. First, we generated a lysine auxotroph of MTBVAC (MTBVACΔ lys ) by deleting the lysA gene. Then the auxotrophic MTBVACΔ lys was transformed with the E…
Abdulkarim S, John S, Garba T, Basason H, Balogun P, et al.
…icating (dormant) state and the increasing global burden of HIV coinfection. Consequently, understanding the knowledge and perception of the population at risk of tuberculosis-HIV infection is essential to designing a strategy of intervention embraced by the target population. A …
Marziye Kazerani, Fatemeh Abedi
HIV-TB co-infection is a major public health threat. HIV complicates every aspect of TB including presentation. The aim of this study was the assessment of some epidemiologic factors HIV-TB co-infection in patients referred to the infection- behavioral disorders center of Mashhad…
Umubyeyi Nyaruhirira A, Scholten JN, Gidado M, Suarez PG
… other infectious diseases, including tuberculosis (TB) and HIV. The authors reflect on experiences with GeneXpert technology for TB detection and opportunities for integration with other diseases. They also reflect on benefits and risks of integration. Placement of diagnostics i…
Nitya Vyas, Jyotsna Chandwani, Sakshee Gupta, Babita Sharma
…etiology during the course of human immunodeficiency virus (HIV) infection. High burden of tuberculosis (TB) among HIV-infected patients leads to lowering of immunity, thus increasing the incidence of other opportunistic infections. The present study was conducted to discuss the …
Armstrong-Hough M, Shelby T, Ggita J, Nangendo J, Gupta AJ, et al.
BACKGROUND Measuring stigma for TB and HIV in households undergoing contact investigation for TB is critical for understanding its impacts on health behaviours and identifying opportunities for intervention. However, standardised measurements for TB-HIV stigma in household contac…
Kyi MS, Aung ST, Oo HN, Chongsuvivatwong V
…ces for tuberculosis (TB) and human immunodeficiency virus (HIV) are operated either fully (as one single unit) or partially (each vertical programme provides both services). OBJECTIVE To review the fully and partially integrated services for TB-HIV and to assess their TB treatme…
Uma Malik, Ghulam Rajput, Dsasui Tunio
A major global health concern is the co-infection of HIV/AIDS and TB, which increases rates of morbidity and mortality. The mortality ratios linked to HIV with TB co-infection are examined in this article through an analysis of epidemiological data of one window Service Treatment…
Mabuza MP, Shumba C
…ssing the high burden of tuberculosis-human immune virus (TBHIV) co-infection, and this challenge is more pronounced in the province of KwaZulu-Natal which has one of the highest burdens of TB-HIV co-infection in the world. The study explored the experiences of doctors and nurses…
Benzekri NA, Sambou JF, Tamba IT, Diatta JP, Sall I, et al.
…ribute to poor adherence to both tuberculosis treatment and HIV antiretroviral therapy (ART). Interventions that target food insecurity have the potential to increase treatment adherence, improve clinical outcomes, and decrease mortality. The goals of this study were to compare t…
Suraj Abdulkarim, Stephen John, Tomon Garba, Hunpiya Basason, Paul Balogun, et al.
…icating (dormant) state and the increasing global burden of HIV coinfection. Consequently, understanding the knowledge and perception of the population at risk of tuberculosis-HIV infection is essential to designing a strategy of intervention embraced by the target population. A …
Alene KA, Viney K, Moore HC, Wagaw M, Clements ACA
…kground Tuberculosis (TB) and human immunodeficiency virus (HIV) are the leading causes of infectious-disease-related deaths in Ethiopia, but little is known about their spatial distribution across the country. The aim of this study was to investigate the spatial patterns of TB a…
Christopher C. Whalen, MD, Roy Mugerwa, MD, Diane Havlir, MD
…his study is designed to determine whether 6 months of anti-HIV drugs given along with tuberculosis treatment will delay the onset of AIDS in HIV infected African patients. Tuberculosis (TB) is a common and serious complication of HIV infection in the developing world, especiall…