Showing 176–200 of 200 documents
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Mwaura M, Engel N
…ckground Diagnosing tuberculosis (TB) in people living with HIV (PLHIV) is challenging due to atypical clinical and radiological presentation and higher rates of sputum-negative or extrapulmonary disease. Urine LAM is a promising diagnostic biomarker to address these challenges. …
Fazal‐e‐Rabi Subhani
…y benefit when adjunctive glucocorticoid therapy is used in HIV-uninfected CNS TB patients. Since data in HIV-infected patients is sparse, the same mortality benefit has not been reproduced thus far in such cases. In a systemic review including nine trials (1337 patients with CNS…
C. Le, Tiffany Truong, Gipshu Dave, Justin Nguyen, Phương Thu Trần, et al.
…nosis of tuberculosis (TB). Children and people living with HIV (PLHIV) are often unable to produce sputum, testing with culture and nucleic acid amplification tests is costly and has long turn-around time, and sputum cannot be used for diagnosis of extrapulmonary TB. Lipoarabino…
Abiona Oluwadamilola Odeyemi, Abiona Oluwadamilola Odeyemi, Abiodun R. Ojewuyi, Abimbola Ololade Odeyemi, Abimbola Ololade Odeyemi, et al.
…register. Data extracted included sociodemographic factors, HIV status, treatment category, rifampicin resistance, extrapulmonary TB, and treatment outcome. Treatment outcome was categorized as successfully treated or poor treatment outcome (death, treatment failure, and lost to …
Novita Maulidiyah, Ramadi Satryo Wicaksono, Aisyah Retnowulan, Budi Santoso, Aries Subianto, et al.
…graphs, and tissue biopsies, the patient was diagnosed with HIV co-infection along with pulmonary and mesenteric TB. Treatment comprised an intensive phase of four fixed-dose combinations (FDC) of anti-TB drugs, followed by a continuation phase of two FDC tablets, alongside first…
Loghin II, Vâță A, Miftode EG, Cobaschi M, Rusu ȘA, et al.
…y. It is well recognized that human immunodeficiency virus (HIV)-positive people are more likely to develop EPTB, including TBM, especially if they have severe immunodeficiencies. We aim to highlight the profile and the characteristics of TBM in HIV-infected patients. Material an…
Olson D, Liu KC, Merza AP, Tilahun E, Aziz Aadam A
…ith increased TB exposure and human immunodeficiency virus (HIV) infection rates. Although TB is not as commonly seen in western populations, it should be considered on the differential for any atypical presentations of GI diseases for patients with clinical or geographic risk fa…
Wagdy Amin, Rasha Ashmawy, Sarah Assem Ibrahim, Yousra A El-Maradny, Neamat Hamdy Elsawy, et al.
…ions who are co-infected with human immunodeficiency virus (HIV) or hepatitis C virus (HCV). This study aimed to assess the incidence and predictors of EPTB in patients co-infected with HIV or HCV in Egypt. We conducted a retrospective cohort study on patients infected with TB wh…
Liu Y, Guo W, Gao S, Luo M, Liang K
…nifestations, hepatic TB with human immunodeficiency virus (HIV) infection is easy to be misdiagnosed. We report a case of hepatic TB with acquired immune deficiency syndrome (AIDS), which was initially misdiagnosed as general bacterial liver abscess even after the patient receiv…
L Fidelle, Raman Mahajan, J Gallo, E Biague, Ramiro Gonçalves, et al.
…ls and urine samples to diagnose TB in children living with HIV (CLWH) in two high-TB burden settings. METHODS This cross-sectional multicentric study took place at Simão Mendes hospital, Guinea-Bissau, from July 2019 to April 2020, and in Malakal hospitals, South Sudan, from Nov…
François Spertini
…died of TB. Co-infection with human immunodeficiency virus (HIV) greatly increases risk of TB reactivation and death. Diagnosis is challenging and drug treatment can be prolonged, harmful, costly and complex. For these reasons an effective TB vaccine is a global public health pri…
Nguyen B. Hoa, Mark Fajans, Hùng Nguyễn Văn, Bao Vu Ngoc, Nhung Nguyen Viet, et al.
…AM) testing by RDT has been approved for people living with HIV, but there is limited data regarding uLAM levels in HIV-negative adults with TB disease. We conducted a clinical study of adults presenting with TB-related symptoms at the National Lung Hospital in Hanoi, Vietnam. Th…
V. Yu. Mishin, А. В. Мишина, Atadzhan Ergeshov, V. V. Romanov, А. L. Sobkin
…obiological and immunological peculiarities in 26 latestage HIV infection patients with pulmonary TB and concomitant mycobacteriosis. They all had CD4+ lymphocyte counts less than 30 cells/μL of blood, did not receive antiretroviral therapy, and excreted both M. tuberculosis and …
Nogueira BMF, Krishnan S, Barreto-Duarte B, Araújo-Pereira M, Queiroz ATL, et al.
…iversal diagnostic TB biomarker, such as people living with HIV, extrapulmonary TB, and children. We also review additional limitations to widespread validation and utilization of published biomarkers. We conclude with proposed solutions to enhance TB diagnostic biomarker validat…
Laura Moretó Planas, MD
…entation, including TB contacts, past TB treatment or known HIV infection; physical examination was conducted in all patients and included relevant anthropometrics (Mid-Upper-Arm Circumference (MUAC), Weight-for-height z scores (WHZ) and/or body mass index (BMI) for age z scores)…
Retno Asih Setyoningrum Indah Ratna Sari
…ization status, contact history with adult TB patients, and HIV (human immunodeficiency virus) infection. Each risk factor was analyzed using Chi-square. Risk factors which were statistically significant (p<0,05) would be analyzed using logistic regression. Results: There were…
Lisa Kurver, Timothy Seers, Suzanne van Dorp, Reinout van Crevel, Gabriele Pollara, et al.
…nt strategies, we integrated all published reports of adult HIV-negative TB-associated HLH (TB-HLH) globally to define clinical characteristics and therapeutic approaches associated with improved survival. Methods PubMed, Embase, and Global Index Medicus were searched for eligibl…
World Health Organization
Hoa NB, Fajans M, Nguyen Van H, Vu Ngoc B, Nguyen Viet N, et al.
…ostic tests (RDTs) has been approved for people living with HIV (PLWH), however there is limited data regarding uLAM levels in HIV-negative (HIV-ve) adults with clinical TB. We conducted a clinical study of adults presenting with clinical TB-related symptoms at the National Lung …
Collin R Diedrich, Tara Rutledge, Janelle L Gleim, Christopher Kline, Pauline Maiello, et al.
Coinfection with both HIV and M. tuberculosis (Mtb) results in disseminated tuberculosis (TB) and accelerated HIV progression. Despite greater access to antiretroviral treatment (ART), it remains unclear whether suppression of HIV replication protects against severe Mtb infection…
Fiske CT, Blackman A, Maruri F, Rebeiro PF, Huaman M, et al.
Background Independent of HIV infection, extrapulmonary TB (EPTB) risk is increased in women, persons of black race or foreign birth, and by genetic variants in vitamin D receptor (VDR), interleukin-1 beta (IL-1β), and toll-like receptor (TLR)-2; functional correlates are unclear…
Tiffeney Mann, Stephanie Minnies, Rishi K Gupta, Byron W P Reeve, Georgina Nyawo, et al.
…referred to hospital for invasive sampling in a high TB and HIV prevalence setting. Multiple blood RNA biomarkers showed comparable diagnostic accuracy to that previously reported for pulmonary TB in both EPTB disease cohorts, irrespective of HIV status. All seven blood RNA bioma…
Laiane Rodrigues Macêdo, Larissa Duarte de Melo, Carolaine Brenda Ridolfi, Myrna Ohana da Costa Lira, L. Simón, et al.
…ographic variables, personal history, clinical aspects, and HIV-TB coinfection. A total of 28,504 tuberculosis cases were identified among the incarcerated population in São Paulo, representing 26.8% of cases nationwide. The highest number occurred in 2017 (3,744 cases; 13.1%). M…
Tomaz APO, Raboni SM, Kussen GMB, da Silva Nogueira K, Lopes Ribeiro CE, et al.
…(i) laboratory and clinical/epidemiological diagnosis; (ii) HIV-positive and -negative populations; (iii) type of specimens: pulmonary and extrapulmonary. Overall, 924 specimens from 743 patients were evaluated. The performance of the assays was evaluated considering culture (Low…
Grazielle Grazielle, Ahmad Rizal Ganiem, Sobaryati Sobaryati, Sofiati Dian, Prayudi Santoso
…21. Demographic and clinical data were collected, including HIV status. TBM cases were classified into grades I, II, and III using Medical Research Counsil (MRC) criteria that were based on Glasgow Coma Scale (GCS) score and the presence of focal neurological deficits. The clinic…