Showing 176–200 of 200 documents
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Katherine Timboe, J Brooks Jackson, Greta L Becker
…ding infectious cause of death globally. Although effective treatments are available, treatment length, drug toxicity, and the emergence of drug-resistant strains have challenged TB control efforts. Current clinical trials are focused on developing shorter, safer, and more effect…
Joyce W.Y. Mak, Joseph J.�Y. Sung
… of concerns for the use of these drugs in the East. First, latent infection is a major threat when using potent immunosuppressive agents. The high prevalence of subclinical or past infection of tuberculosis, viral hepatitis, and other latent infections poses potential danger of …
Judi Chen, Weining Cao, Renfang Chen, Yong Ren, Tao Li
…an immunodeficiency virus (HIV) worldwide are infected with latent tuberculosis (TB). The aim of this study was to determine the rate of HIV infection in TB patients and its determinants in Wuxi City, China. TB patients attending health institutions (12 selected sites) for TB dia…
Chitnis AS, Cheung R, Gish RG, Wong RJ
…nic hepatitis B virus (CHB) infection can be prevented with treatment and vaccination, respectively. We reviewed epidemiology and guidelines for TB and CHB to inform strategies for reducing United States (U.S.) burden of both infections. Non-U.S.-born, compared to U.S.-born, pers…
Ronald LA, Campbell JR, Balshaw RF, Romanowski K, Roth DZ, et al.
Background Canadian tuberculosis (TB) guidelines recommend targeting postlanding screening for and treatment of latent tuberculosis infection (LTBI) in people migrating to Canada who are at increased risk for TB reactivation. Our objectives were to calculate robust longitudinal e…
Ghassan Ilaiwy, Jessica Keim‐Malpass, Romella Tuppal, Alexander F. Ritua, Flordeliza R. Bassiag, et al.
…d a cost effectiveness analysis evaluating the expansion of latent TB testing and treatment among pediatric (5-14 years) household contacts of index TB patients in the Philippines. Methods : Using a Markov state transition model, eligible household contacts (HHCs) age 5-14 years …
S Pappas, Y Zhu, S Hegeman, D S Mohamed, N Kalra, et al.
…sts between Omalizumab and pulmonary disease, nor are there guidelines recommending TB screening before therapy [6]. A single report described a 32-year-old Filipino woman diagnosed with pulmonary and extrapulmonary TB after starting Omalizumab for CSU [7]. Mast cells play a para…
Grasa Lozano CD, Baro-Fernández M, Rubio-San-Simón A, Blázquez-Gamero D, López-Roa P, et al.
Background There are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected. Methods After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time …
Arafa Djalal, Justin Côté-Daigneault
Inflammatory bowel disease (IBD) patients undergoing treatment with biological therapy are at increased risk of developing opportunistic infections such as tuberculosis (TB). Screening for latent tuberculosis is mandatory before initiating biological therapy such as Anti-TNF alph…
R. De Luca E Tuma, Amina Jama, Susan Dart, Verónica White, Christabelle Chen, et al.
…of MDR-TB in East London remain high. There are no existing guidelines for treating close contacts of newly diagnosed MDR-TB cases in low TB incidence countries. This study aims to analyze the rates of MDR-TB among close contacts of TB index cases with pulmonary MDR-TB in East Lo…
World Health Organization. Regional Office for Europe
…lding for consultants on the new WHO recommendation for the treatment of drug-resistant tuberculosis” on 15–18 June 2020. The objectives of the training session included capacity-building of the new and existing regional Green Light Committee for the WHO European Region (rGLC/Eur…
Maria Mironova, Irina Y. Gutierrez Puentes, Rajashree Anandakrishnan, Anil R. Balani
…or necrosis factor alpha (anti-TNF) medication used for the treatment of moderate-to-severe Crohn’s disease and ulcerative colitis. Tuberculosis (TB) has remained a serious side effect of anti-TNF therapy despite routine TB screening. We report a case of a young male who develope…
Pop R, Kaelin MB, Kuster SP, Sax H, Rampini SK, et al.
…d exposure to sputum smear positive tuberculosis (TB). NICE guidelines give support regarding investigation and treatment intervention, but not for contact definitions. Data regarding the reliability of any interferon gamma release assay (IGRA) in infants as a screening test for …
Farah Daas, Rafael Ruiz‐Gaviria, Bhakti Thummar, Naveera Khan, Sheena Ramdeen
…y (IGRA) is frequently ordered in hospitalized patients for latent tuberculosis (TB) screening. Health care workers must be cautioned that acute and critical illness exert a significant effect on IGRA performance, so delaying screening to the outpatient setting is preferred if fe…
Djalal A, Côté-Daigneault J
…ground Inflammatory bowel disease (IBD) patients undergoing treatment with biological therapy are at increased risk of developing opportunistic infections such as tuberculosis (TB). Screening for latent tuberculosis is mandatory before initiating biological therapy such as Anti-T…
Karat AS, Gregg M, Barton HE, Calderon M, Ellis J, et al.
…n to inform the 2019 update of global tuberculosis (TB) IPC guidelines, asked: do triage and/or isolation and/or effective treatment of TB disease reduce MTB transmission in healthcare settings? Of 25 included articles, 19 reported latent TB infection (LTBI) incidence in healthca…
Rebecca Berhanu, Karen R. Jacobson
…st benefit is observed in those with a positive result on a latent TB infection test, which is not ...References1. Samandari T, Agizew TB, Nyirenda S, et al. 6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a random…
Kendra Brett, Melissa Severn
It is not known if screening for latent tuberculosis infection (LTBI) is useful for reducing the risk of tuberculosis reactivation among people at risk (no evidence was found). In people with LTBI, providing treatment for the latent infection may be helpful for preventing the dev…
Adrienne E. Shapiro, Ayushi Gupta, Kristine F Lan, H. Nina Kim
…in the US is reactivation TB in non-US-born (nUSb) persons. Guidelines recommend screening persons born in high TB burden countries for latent TB infection (LTBI) and treating if positive. We evaluated the LTBI cascade in primary care among nUSb persons in a large academic medica…
…in the US is reactivation TB in non-US-born (nUSb) persons. Guidelines recommend screening persons born in high TB burden countries for latent TB infection (LTBI) and treating if positive. We evaluated the LTBI cascade in primary care among nUSb persons in a large academic medica…
World Health Organization
…perience since the publication of the 2021 consolidated HIV guidelines and aims to support progress towards ending AIDS as a public health threat by 2030. The document addresses the use of preferred and alternative antiretroviral regimens across different populations, including a…
Faiza Aiman Khan
…nd the world emphasize on its early detection and immediate treatment to reduce the transmission of infectious cases Primary Health care providers play an essential role in detecting and diagnosing suspected TB cases, and referring them for treatment, thus helping to prevent spre…
Carlo Foppiano Palacios, Amit C. Achhra, Lydia Barakat, Michael Virata, Richie Hao, et al.
…at increased risk of reactivation of tuberculosis (TB) from latent tuberculosis infection (LTBI). Current guidelines recommend all PWH be initially screened for LTBI with either interferon-gamma release assays (IGRA) or tuberculin skin testing (TST). Also, repeat screening is rec…
Nunzi A, Della Valle L, Lindfors Rossi EL, Ranucci G, Mallegni F, et al.
Background Identification of latent tuberculosis infection (LTBI) is a critical step of tuberculosis surveillance, especially in low-incidence countries. However, it is limited to situations with a higher probability of developing active disease, e.g., patients with hematological…
Suman Majumdar, Rina Triasih, Stephen M. Graham
…is by 2030 cannot be achieved without a strategy to address latent infection that is subclinical or quiescent.2Rangaka MX Cavalcante SC Marais BJ et al.Controlling the seedbeds of tuberculosis: diagnosis and treatment of tuberculosis infection.Lancet. 2015; 386: 2344-2353Summary …