Showing 176–200 of 200 documents
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Abdillah Farkhan, Saranath Lawpoolsri, Ngamphol Soonthornworasiri, Tiffany Tiara Pakasi, Sulistyo Sulistyo, et al.
**BACKGROUND:** Indonesia ranks among the countries with the highest burden of drug-resistant tuberculosis (DR-TB), contributing approximately 7.4% of global cases, many of which are likely underdiagnosed. To support targeted public health surveillance and control efforts, this s…
Lin D, Wang J, Cui Z, Ou J, Huang L, et al.
Background Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis (Mtb). China is the third in top 8 high TB burden countries and Guangxi is one of the high incidence areas in South China. Determine bacterial factors that affected TB incidence rate is a step…
Ibrahim Khalil, Sakib Abrar, I M Khalid Reza, Md Imran Hossain, Mst Mahmuda Akter, et al.
**BACKGROUND:** Multidrug-resistant tuberculosis (MDR-TB) remains a major public health challenge in South Asia, which bears a disproportionate global burden. Comprehensive, longitudinal analyses of MDR-TB mortality trends, stratified by country and sex, with forward-looking proj…
Gaensbauer JT, Dash N, Verma S, Hall DJ, Adler-Shohet FC, et al.
Pediatric multidrug-resistant tuberculosis (MDR-TB) remains a significant global problem, and there are numerous barriers preventing children with MDR-TB from being identified, confirmed with microbiologic tests, and treated with a safe, practical, and effective regimen. However,…
Desel T, Tsuda N, Tsundue T, Lingtsang R, Topgyal S, et al.
Abstract Background Globally, refugee populations face an increased risk for tuberculosis (TB) due to malnutrition, overcrowding, and poor living conditions. Compared with the general Indian population, Tibetan refugees in India display a higher incidence rate of both TB and mult…
Khan AS, Khan MT, Ali S, Khan TA, Qasim M, et al.
Regardless of a plethora of advanced diagnostics, TB and drug resistance remains a principal killer. We proposed gold nanoparticles (AuNPs) attached with probes to enhance the efficiency of GeneXpert MTB/RIF assay instead of conventional dye probes for molecular detection. A tota…
Naidoo K, Perumal R, Cox H, Mathema B, Loveday M, et al.
Drug-resistant tuberculosis (DR-TB) threatens to derail tuberculosis control efforts, particularly in Africa where the disease remains out of control. The dogma that DR-TB epidemics are fueled by unchecked rates of acquired resistance in inadequately treated or non-adherent indiv…
Zhang R, Luo S, Wang N, Zhang H, Wu X
Background Nontuberculous mycobacteria (NTM) are easily misdiagnosed as multidrug-resistant tuberculosis (MDR-TB), and treatment drugs are very limited. The main objective of our study was to evaluate the minimal inhibitory concentration (MIC) in vitro of bedaquiline (BDQ), clofa…
Modipane L, Reva O, Magazi BT, Antiabong JF, Osei Sekyere J, et al.
Background Mycobacterium bovis BCG is a live, attenuated tuberculosis vaccine. While the vaccine protects infants from tuberculosis, complications including disseminated infections have been reported following vaccination. Genetically diverse BCG sub-strains now exist following c…
Kassa GM, Merid MW, Muluneh AG
Background Rifampicin and/or multidrug-resistant tuberculosis (RR/MDR-TB) remains an uncontrolled public health emergency that has been synergized by the recently increased person-to-person transmission in the community as primary RR/MDR-TB, which is defined as RR/MDR-TB in new T…
Lin Q, Shrestha S, Zhao S, Chiu APY, Liu Y, et al.
Tuberculosis (TB) incidence has been in steady decline in China over the last few decades. However, ongoing demographic transition, fueled by aging, and massive internal migration could have important implications for TB control in the future. We collated data on TB notification,…
Wu Q, Wang M, Zhang Y, Wang W, Ye TF, et al.
Background The burden of pulmonary tuberculosis (TB) and diabetes mellitus (DM) have become serious global concerns, while the comprehensive evaluations of DM status and drug resistance in TB patients are still lacking. Methods All details of TB cases were collected from drug res…
Lu Z, Jiang W, Zhang J, Lynn HS, Chen Y, et al.
As China is one of high MDR-TB burden countries, it is important to determine the drug resistant pattern and clinical characteristics of multidrug resistant tuberculosis (MDR-TB). We conducted a comprehensive and nationwide study on MDR-TB in 17 provinces for the period from June…
Chathika K. Weerasuriya, Rebecca C. Harris, Christopher Finn McQuaid, Fiammetta Bozzani, Yunzhou Ruan, et al.
The original article contained errors in the Abstract which have all since been corrected.
Zhai PY, Chen ZX, Jiang T, Feng J, Zhang B, et al.
This study used a calibrated mathematical model to evaluate age-specific tuberculosis (TB) vaccination strategies, for drug-resistant (DR)-TB management in China. Prioritizing elderly vaccination significantly reduced multidrug-resistant or rifampicin-resistant TB incidence and m…
MacNeil A, Glaziou P, Sismanidis C, Maloney S, Floyd K
Worldwide, tuberculosis (TB) is the leading cause of death from a single infectious disease agent (1) and the leading cause of death among persons living with human immunodeficiency virus (HIV) infection, accounting for approximately 40% of deaths in this population (2). The Unit…
Yang J, Zheng X, Zhang S, Wang H
This research was to explore the population characteristics and drug-resistant gene mutations of tuberculosis (TB) and human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) dual infection population, and to provide a reference for clinical screening and pr…
Abbasian S, Heidari H, Abbasi Tadi D, Kardan-Yamchi J, Taji A, et al.
Drug resistance among Mycobacterium tuberculosis (MTB) strains is a growing concern in developing countries. We conducted a comprehensive search for relevant studies in Iran on PubMed, Scopus, and Embase until June 12, 2020. Our study focused on determining the prevalence of anti…
Nan Wang, Fanrong Meng, Li Deng, Ling Wu, Yu Yang, et al.
This study investigates the epidemic trend of pyrazinamide (PZA)-resistant tuberculosis in Southern China over 11 years (2012-2022) and evaluates the mutation characteristics of PZA resistance-related genes (and) in clinical() isolates. To fulfil these goals, we analyzed the phen…
Asare P, Osei-Wusu S, Baddoo NA, Bedeley E, Otchere ID, et al.
Objective To retrospectively investigate the cause of recurring tuberculosis (rcTB) among participants with pulmonary TB recruited from a prospective population-based study conducted between July 2012 and December 2015. Methods Mycobacterium tuberculosis complex isolates obtained…
Thumamo Pokam BD, Yeboah-Manu D, Amiteye D, Asare P, Guemdjom PW, et al.
Background Tuberculosis ( TB) and drug-resistant TB (DR-TB) continue to persist as a serious public health challenges in Ghana. Although several research has evaluated the drug resistance of Mycobacterium tuberculosis complex (MTBc) strains across the country, there is a paucity …
Ally Yeketi Ayinla
This project analyses the tuberculosis (TB) epidemic mathematically using compartmental modelling approach. Three models are presented to discuss drug susceptible and multi-drug resistant TB. The first model presented has 4 compartments; susceptible, exposed, infectious and recov…
Ramazanzadeh R, Shakib P, Rouhi S, Mohammadi B, Mohajeri P, et al.
Spoligotyping can help assess the transmission of Mycobacterium tuberculosis strains. We aimed to study the genotyping of M. tuberculosis isolated from patients with tuberculosis from the west of Iran by spoligotyping. Forty-seven M. tuberculosis isolates were collected from the …
Sebastião CS, Samulengo J, Sacomboio E, Francisco NM, Teixeira C, et al.
Tuberculosis (TB) is a major cause of illness and public health concern, especially in resource-limited countries. This study analyzed the characteristics related to anti-TB drug resistance. Moreover, we examined the evidence-based indications for the treatment of active TB in An…
Huang H, Ding N, Yang T, Li C, Jia X, et al.
Background The increase in multidrug-resistant tuberculosis (MDR-TB) severely hampers tuberculosis prevention and control in China, a country with the second highest MDR-TB burden globally. The first nationwide drug-resistant tuberculosis surveillance program provides an opportun…