Showing 176–200 of 200 documents
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Yerlikaya S, Holtgrewe LM, Broger T, Isaacs C, Nahid P, et al.
…ty target product profiles (TPPs) for new tuberculosis (TB) diagnostics to align end-user needs with test targets and specifications; nevertheless, no TB test meets these targets to date. The COVID-19-driven momentum in the diagnostics world offers an opportunity to address the l…
Zhang X, Meng Q, Miao R, Huang P
Background Tuberculous infection of T cell spot test (T-SPOT.TB) and adenosine deaminase (ADA) have a high diagnostic value in pleural effusion for tuberculous pleurisy. However, there were major differences in existing research in regard to the clinical application of the two tr…
Bankole OT, Ajayi IO
The prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection in Nigeria is currently around 19.1%. This indicates that the two diseases are still a burden on the nation"s health. The aim of this study was to evaluate the diagnostic microbiology capacity …
Engel N
…ted in global innovation practices for tuberculosis and HIV diagnostics, and to what effect. It examines the development of point-of-care (POC) diagnostics - promised to be designed for users outside laboratories or in resource constrained settings - to study what developers and …
Tehreem Zulfiqar Janjua, Saqib Musharaf, Arooba Zulfiqar Janjua, Faisal Hassan Zahid Chaudhery, Farzeen Bakhtawar, et al.
Pulmonary tuberculosis (PTB) remains a significant public health concern, especially in high-burden countries like Pakistan. Diagnosis becomes particularly challenging in sputum-negative patients, leading to delayed treatment and increased transmission. Bronchoalveolar lavage (BA…
Zhang Y, Zhan B, Hao X, Wang W, Zhang X, et al.
Purpose Tuberculosis is a high-burden disease and a major health concern in China, especially among children and adolescents. The purpose of this study was to assess risk factors for diagnostic delay in students with pulmonary tuberculosis in Quzhou City in eastern China. Patient…
Yadav D, Garg RK, Chhabra D, Yadav R, Kumar A, et al.
…resent work illustrates the promising intervention of smart diagnostics devices through artificial intelligence (AI) and mechanobiological approaches in health care practices. The artificial intelligence and mechanobiological approaches in diagnostics widen the scope for point of…
Rina Triasih
In general, the diagnosis of COVID-19 in children is the same as that in adults, which is based on the clinical and epidemiological history of the patient. Clinicians should have a suspicion of COVID-19 when a child shows one or more clinical manifestations of COVID-19 and, withi…
Robert Needle, Yang Yu, Hafid Soualhine, Catherine Yoshida, Lei Jiao, et al.
…ycobacterial (NTM) infections is accomplished by three main diagnostics methods: smear microscopy, culture, and molecular testing. Diagnostic algorithms used by laboratories can significantly impact clinical and infection control management. Current Canadian Tuberculosis Standard…
Takumi Kanokogi, Naohisa Urabe, Nozomi Tokita, Hinako Murakami, Masakazu Sasaki, et al.
The incremental diagnostic yield of consecutive sputum nucleic acid amplification tests (NAATs) for pulmonary tuberculosis (PTB) is not well established. We aimed to assess the diagnostic performance of one to three consecutive sputum NAATs in a non-high-tuberculosis-burden setti…
Chang Song, Chunyan Zhao, Dan Luo, Aichun Huang, Chaoyan Xu, et al.
**BACKGROUND:** Tuberculosis (TB) remains a major cause of death in HIV/AIDS patients, where diagnosis is complicated by atypical presentation and paucibacillary disease. Current diagnostic methods have limitations in speed or sensitivity. This study evaluates the diagnostic valu…
Bjørn Waagsbø, Eva Margrethe Buset, Jørn-Åge Longva, Merete Bjerke, Birgitte Bakkene, et al.
PURPOSE: Studies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, retrospective, regional study from Norway, our primary object…
Lin D, Wang X, Li Y, Wang W, Li Y, et al.
The prevalence of drug-resistant Mycobacterium tuberculosis (Mtb) strains makes disease control more complicated, which is the main cause of death in tuberculosis (TB) patients. Early detection and timely standard treatment are the key to current prevention and control of drug-re…
Cherian SV, Kaur S, Karanth S, Xian JZ, Estrada-Y-Martin RM
Introduction Electromagnetic navigational bronchoscopy (ENB) is an excellent tool to diagnose peripheral pulmonary nodules, especially in the setting of emphysema and pulmonary fibrosis. However, most of these procedures are done by interventional pulmonologists and academic tert…
Limsrivilai J, Pausawasdi N
Differentiating Crohn's disease (CD) from intestinal tuberculosis (ITB) is a diagnostic dilemma, particularly in regions where ITB is prevalent and CD incidence is increasing, because both diseases can present quite similarly, and diagnostic tests to identify Mycobacterium tuberc…
Bjørn Waagsbø, Eva Margrethe Buset, Jørn-Åge Longva, Merete Bjerke, Birgitte Bakkene, et al.
Abstract PurposeStudies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, retrospective, regional study from Norway, our primary…
Qanash S, Hakami OA, Al-Husayni F, Gari AG
Objective Flexible fiberoptic bronchoscopy (FFB) has become an essential procedure for diagnosing and managing various respiratory conditions. We aimed to assess the main indications, diagnostic yield, and safety of FFB in our institute. Methods A total of 216 patients who underw…
Di Gennaro F, Cotugno S, Guido G, Cavallin F, Pisaturo M, et al.
Background Tuberculosis (TB) remains a Global Health challenge, with diagnostic delays contributing significantly to its spread. This study investigates the differences in diagnostic delays between native and migrant TB patients in Italy, examining patient-related diagnostic dela…
Rangasamy Ramanthan, M. Jayapritha
…ngs, to improve TB detection. Expanding access to molecular diagnostics and integrating nutritional interventions are essential for better management.
Banerjee R, Pal P, Girish BG, Reddy DN
Background The diagnosis of Crohn's disease (CD) can be delayed in clinical practice. In tuberculosis endemic areas, empirical anti-tubercular therapy further delays treatment. Aim(s) To assess risk factors for diagnostic delay and its impact on the long-term complications of Cro…
Ng KC, Meehan CJ, Torrea G, Goeminne L, Diels M, et al.
…s have adopted connectivity solutions that allow linking of diagnostics, real-time capture, and shared repository of these test results. However, these connected diagnostics and readily available test results are not used to their full capacity, as we have yet to capitalize on fu…
Hangxing Wang, Yuanchun Li, Lifan Zhang, Xiaoqing Liu
**BACKGROUND AND OBJECTIVES:** Patients with rheumatic immune diseases (RD) are considered a high-risk population for developing active tuberculosis (ATB). Timely and accurate diagnosis of ATB in RD patients is critical for optimizing treatment outcomes and improving prognosis. B…
Qu H, Wang M, Wang Z, Ao G, Yuan X, et al.
Rationale and objectives This prospective study aimed to evaluate the diagnostic performance of dual-input computed tomography perfusion technique (DI-CTP) in identifying the bronchial-pulmonary artery fistula in patients tuberculosis with massive hemoptysis. Material and methods…
Andama A, Somoskovi A, Mandel B, Bell D, Gutierrez C
…ug resistant TB. The ultimate goal is to improve laboratory diagnostics and better individualized managementof detected TB, and make an important contribution toward eliminating this global epidemic. RATIONALE: Tuberculosis persists as one of the world's most deadly infectious di…
Modlin SJ, Mansjö M, Werngren J, Ejike CM, Hoffner SE, et al.
…TB) reported as PZA-susceptible (PZA-S) by common molecular diagnostics. Phenotypic susceptibility testing (pDST) indicated PZA-R TB. Targeted Sanger sequencing reported wild-type PncA, indicating PZA-S TB. Whole Genome Sequencing (WGS) by PacBio and IonTorrent both detected dele…