Showing 126–150 of 200 documents
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Yang J, Zheng X, Zhang S, Wang H
…ions of tuberculosis (TB) and human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) dual infection population, and to provide a reference for clinical screening and prevention of TB/HIV dual infection. TB patients and HIV-infected/AIDS patients registered …
Jason E Farley, PhD, MPH, NP
…programmatic management alone, in patients with and without HIV co-infection. To do this, the researchers will review the medical information collected at the hospital as part of the patient's treatment after obtaining the patient's permission. Mycobacterium tuberculosis (TB) re…
Habimana DS, Ngabonziza JCS, Migambi P, Mucyo-Habimana Y, Mutembayire G, et al.
… important opportunistic infection among people living with HIV (PLHIV). In 2005, Rwanda launched the programmatic management of MDR/RR-TB. The shorter MDR/RR-TB treatment regimen (STR) has been implemented since 2014. We analyzed predictors of MDR/RR-TB mortality, including the …
Tegegn Mulatu Ayana, Kedir Teji Roba, Myrla Obejero Mabalhin
…residence (AOR: 1. 98; 95% CI: 1.01,3.86), co-infection TB- HIV (AOR: 2.15; 95% CI:1.02, 4.56), presence of at least one chronic disease (AOR:3.04; 95% CI:1.59,5.79), experience of stigma (AOR: 1.71; 95% CI:1.01, 2.90), Pulmonary and MDR-TB (AOR:2.53; 95% CI:1.50,4.28) and smokin…
M. Joseph John, Semvua Hadija, Massay Oliva, Nyombi Balthazar, Jaffu Chilongola
…worsened by co-infection with Human immunodeficiency virus (HIV). In order to institute successful TB control strategies, factors for development of MDR-TB must be understood. This study aimed to identify and describe clinical and demographic determinants for development of MDR-T…
Aymar Akilimali, Hugues Cakwira, Chrispin Biamba, Malik Olatunde Oduoye, Fabrice Kibukila, et al.
…d in Africa for susceptible TB, eighth in Africa for TB and HIV co-infection and multidrug-resistant TB7. In the year 2021, despite the occurrence of the COVID-19 pandemic, the DR Congo, through its National Tuberculosis Control Program (NTBCP), notified more than 216 690 cases o…
Baluku JB, Nabwana M, Mwanahamisi SB, Kansiime G, Nuwagira E, et al.
…arly (≤2 months) culture conversion (ECC) among people with HIV and drug-resistant tuberculosis (DRTB) in Uganda. Methods This was a countrywide retrospective cohort of people with bacteriologically confirmed DRTB and a positive baseline culture at 16 centres in Uganda between 20…
Panova AE, Vinokurov AS, Shemetova AA, Burmistrova IA, Shulgina MV, et al.
…develop drug-resistance. Results Clinical MTB isolates from HIV- and HIV+ patients from four regions of Russia were analyzed for genotypes and mutations conferring resistance to Isoniazid, Rifampicin, Ethambutol, aminoglycosides, and fluoroquinolones. Analysis of genotypes and po…
Scherer J, Locketz M, Castelein S, Dunn R, Held M, et al.
…the highest prevalence of people with tuberculosis (TB) and HIV coinfection globally. People living with HIV have an increased risk of TB infection, and are more likely to develop extrapulmonary TB. Approximately 10 - 20% of extrapulmonary TB accounts for skeletal TB, with spinal…
Marme G, Kuzma J, Zimmerman PA, Harris N, Rutherford S
…resistant TB (MDR TB), and TB-human immunodeficiency virus (HIV) co-infections. TB infection prevention and control (TB-IPC) guidelines were introduced in 2011 by the National Health Department of PNG. This study assesses the implementation of this policy in a sample of district …
Carrie Tudor, Jason E. Farley, Martie van der Walt, Susan E. Dorman, William Pan, et al.
…ompared with those without such a history. HCWs living with HIV had a greater incidence of TB (IRR 3.2, 95% CI 1.54-6.66) than HIV-negative HCWs. TB incidence among HCWs was approximately two-fold greater than that of the general population over the study period. Conclusions HCWs…
Olivier Marcy, MD, PhD, Maryline Bonnet, MD, PhD, Eric Wobudeya, MD, PhD
…ng from 4% to 21% \[8\], with younger age, malnutrition and HIV infection increasing the risk of death. The current standard of care (SOC) for young children with pneumonia considers a diagnosis of TB only if the child has a history of prolonged symptoms or fails to respond to a…
Seid A, Girma Y, Abebe A, Dereb E, Kassa M, et al.
…nges global TB control and prevention efforts, where the TB/HIV co-infection epidemic makes the situation much worse. The aim of the study was to determine the determinant factors associated with patterns of MDR-TB among pulmonary TB patients in the Northwest Amhara, Ethiopia. Me…
Lazarus G, Tjoa K, Iskandar AWB, Louisa M, Sagwa EL, et al.
…B) treatment, especially with human immunodeficiency virus (HIV) co-infection, remains a major threat to poor DR-TB treatment adherence and outcomes. This meta-analysis aims to investigate the effect of HIV infection on the development of AEs during DR-TB treatment. Methods Eligi…
Hurtado RM, Meressa D, Goldfeld AE
…t of drug-resistant tuberculosis (TB) in people living with HIV, including early access to timely diagnostics, linkage into care, TB treatment strategies including the use of new and repurposed drugs, co-management of HIV disease, and treatment complications and programmatic supp…
Pushpender Singh, Amit Kumar, Rajan Kumar, Sahil Mehta
…viduals. Latent TB can become active due to factors such as HIV infection, age, diabetes, and close contact with active TB cases. TB remains a signicant global health challenge, with millions of new cases reported annually, causing substantial morbidity and mortality. Multidrug-…
Adetunji SO, Donbraye E, Ekong MJ, Adetunji BI
A major opportunistic infection among HIV-infected people is tuberculosis (TB). It accelerates the deadly progression of HIV which results in further decline in the patient's immune status and early death. More than 9 million people suffer from this debilitating coinfection world…
N Kunle-Ope Chioma, Abraam Isaac, O Iwalokun Bamidele, T Igbasi Uche, Onyejepu Nneka, et al.
… The aim of this work is to determine the rate of MDR-TB in HIV-negative patients with signs and symptoms of pulmonary tuberculosis in Lagos State. 891 adult HIV-negative patients enrolled for the study and tested for acid-fast bacilli by culture; resistance to first-line anti-tu…
Geiger K, Bergman A, Farley JE
…esistant TB (MDR-TB) frequently occur in people living with HIV. World Health Organization guidelines recommend the integration of MDR-TB and HIV care but, in practice, fully integrated care is difficult to achieve. In this article, we use five elements of the Chronic Care Model …
Govender T, Furin JJ, Edwards A, Pillay S, Murphy RA
…oviding an opportunity to examine person-centered DR-TB and HIV care from the perspective of patients who lost access to it. Methods The impact of transfer was explored through qualitative interviews performed using standard methods. Analysis involved grounded theory; interviews …
Choi J, Park J, Son Y, Kim S, Kwon R, et al.
Objective Currently, human immunodeficiency virus (HIV) and multi-drug resistant tuberculosis (MDR-TB) without extensive drug resistance (XDR) are significant challenges in terms of the global burden of disease. This study aimed to evaluate the trends of the global burden of MDR-…
Kenaope L, Ferreira H, Seedat F, Otwombe K, Martinson NA, et al.
…he confirmatory DST in a high human immunodeficiency virus (HIV) seroprevalence setting. Design Records analysing demographics, HIV serostatus, prior TB treatments, and DST results were retrospectively reviewed. Results Of 604 patients with X-pert MTB/RIF RR, 374 (61.9%) had DST …
Vila Torres SG, Fullmer J, Berkowitz L
… with pulmonary tuberculosis, human immunodeficiency virus (HIV), and syphilis. His TB isolate was found to be resistant to multiple anti-TB drugs, presenting unusual challenges in treating multidrug-resistant TB with HIV co-infection.
Muhammad Tahir, Syed İnayat Ali Shah, Gul Zaman
…nter; $${V_3}$$, co-treatment of multidrug-resistant TB and HIV or start both HIV antiretroviral and anti-TB drug therapy; and $${V_4}$$, avoid close contact with TB patient. These are defined with some different schemes to minimize and control the infection from any community an…
Abubakar A. Abdulazeez, Adeniran A. Margaret, Nassar Adebayo Sulaiman, Abdulazeez I. Abdulazeez
…ty rates Objective: To assess the frequency of MDR-Tb among HIV sero-positive and sero-negative populations in Ilorin, North-Central Nigeria. Method: Sputum samples were collected from 1,601 subjects provisionally diagnosed with pulmonary tuberculosis (TB) at Sobi Specialist Hosp…