Showing 126–150 of 200 documents
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Hasniah Halisan, Ramadhan Tosepu, La Ode Muhamad Sety
TB and HIV co-infection occurs when a person has active or latent TB and HIV infection. HIV-positive sufferers have a 30 times greater risk of getting TB than HIV-negative people. This study aimed to analyze the prevalence of pulmonary tuberculosis in HIV/AIDS patients based on t…
Friedman EE, Khan A, Duffus WA
…ng for latent tuberculosis (TB) infection among people with HIV is recommended, but the percentage receiving screening is unknown. This study assessed screening for latent TB infection among people with HIV enrolled in Medicaid during 2006-2010. Methods We used nationwide fee-for…
Sensalire S, Karungi Karamagi Nkolo E, Nabwire J, Lawino A, Kiragga D, et al.
…kground Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection constitute a deadly infectious disease synergy disease and major public health problem throughout the world. The risk of developing active TB in people living with HIV (PLHIV) is 21 times higher than th…
Meier NR, Battegay M, Ottenhoff THM, Furrer H, Nemeth J, et al.
Background: In individuals living with HIV infection the development of tuberculosis (TB) is associated with rapid progression from asymptomatic TB infection to active TB disease. Sputum-based diagnostic tests for TB have low sensitivity in minimal and subclinical TB precluding e…
Kendra Brett, Camille Dulong, Melissa Severn
…sult from diseases that compromise the immune system (e.g., HIV infection, autoimmune disease, cancer), or from treatments that cause immunosuppression (e.g., anti-rejection drugs for transplant recipients, or tumor necrosis factor (TNF) inhibitors)., Patients with compromised im…
Brett K, Dulong C, Severn M
…sult from diseases that compromise the immune system (e.g., HIV infection, autoimmune disease, cancer), or from treatments that cause immunosuppression (e.g., anti-rejection drugs for transplant recipients, or tumor necrosis factor (TNF) inhibitors)., Patients with compromised im…
Anye CS, Nkfusai CN, Yankam BM, Wirsiy FS, Tsoka-Gwegweni JM, et al.
…kground Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) co-infections place immense burdens on healthcare systems with particularly diagnostic and therapeutic challenges. TB is high among opportunistic diseases and the most leading cause of death among patients with HIV/…
Sridhar R, Vinod Kumar V, Kumar S
… article highlights the impact of LTBI particularly among PLHIV, WHO recommendations for the diagnosis and management of LTBI, various treatment options for the management of LTBI and research priorities to address LTBI better.
Bhosale R, Alexander M, Deshpande P, Kulkarni V, Gupte N, et al.
…ests are critical for pregnant women, especially those with HIV, who have a high risk of TB disease. Methods We enrolled interferon gamma release assay (IGRA)+ pregnant women with and without HIV in a longitudinal study, followed up at delivery and 6 months postpartum. Tuberculin…
Stephen A Migueles, M.D.
…threat for people living with human immunodeficiency virus (HIV). People living with HIV are more likely than others to develop active TB. Also, TB makes HIV progress faster. TB is a leading cause of death among people in the West African country of Liberia. Researchers want to f…
Wycliff Ssekayi, Edity Namyalo, Josephine Namayanja, Joseph Kungu
…morbidity and mortality among human immunodeficiency virus (HIV) infected individuals in Sub Saharan Africa, including Uganda. Isoniazid prophylaxis therapy (IPT) is a major public health intervention to avert the progression of latent tuberculosis to active tuberculosis disease …
J Marwa K, Maingu R
Background People infected with HIV are at a higher risk up to 20-folds of developing active TB than those not infected with HIV. Isoniazid Preventive Therapy (IPT) is employed in HIV eligible individuals to prevent progression of active tuberculosis (TB) disease. However, there …
Elisa H Ignatious, Susan Swindells
…s (TB) remains the leading cause of death among people with HIV, and annual risk of progression from latent TB infection to active disease in this population is 10%. Diagnostic tests for latent and active TB remain suboptimal for people with HIV who have a CD4+ count below 200 ce…
Ignatious EH, Swindells S
…s (TB) remains the leading cause of death among people with HIV, and annual risk of progression from latent TB infection to active disease in this population is 10%. Diagnostic tests for latent and active TB remain suboptimal for people with HIV who have a CD4+ count below 200 ce…
Yagnesh Dhiren Doshi, Anita Basavaraj
…infection contributes to high morbidity and mortality among HIV seropositive persons. As per World Health Organisation TB statistics for 2020, and the India TB Report 2021- The incidence of TB cases including HIV in India was 193 per 100000 population, of which mortality was 32 p…
Nanda Rachmad Putra Gofur, Aisyah Rachmadani Putri Gofur
…inical manifestations of tuberculosis in the oral cavity in HIV patients. Discussion: Mycobacterium tuberculosis is slowly replicating intracellular pathogen in macrophages that elicits a T cell immune response mediated by antigen-specific CD4+ and CD8+ T cells. This immune respo…
Wong NS, Chan KCW, Wong BCK, Leung CC, Chan WK, et al.
…sk of tuberculosis (TB) reactivation among individuals with HIV could be reduced. The current strategy of annual latent TB infection (LTBI) testing should be revisited to increase cost-effectiveness and reduce the intensity of testing for individuals. Objective To analyze the cos…
Devalraju KP, Neela VSK, Chintala S, Krovvidi SS, Valluri VL
…ytokines by peripheral blood mononuclear cells (PBMCs) from HIV - and HIV + individuals with latent and active Tuberculosis infection in response to Mtb Antigen 85A. PBMCs from HIV + LTBI + and HIV + active TB patients produced low IL-1β, IL-2 but high transforming growth factor …
Ganatra SR, Bucşan AN, Alvarez X, Kumar S, Chatterjee A, et al.
…tuberculosis (TB) remains the leading cause of death in the HIV-infected population. We used Mycobacterium tuberculosis/simian immunodeficiency virus-coinfected (M. tuberculosis/SIV-coinfected) macaques to model M. tuberculosis/HIV coinfection and study the impact of ART on TB re…
Bunjun R, Omondi FMA, Makatsa MS, Keeton R, Wendoh JM, et al.
HIV-1 infection substantially increases the risk of developing tuberculosis (TB). Mechanisms such as defects in the Th1 response to Mycobacterium tuberculosis in HIV-infected persons have been widely reported. However, Th1-independent mechanisms also contribute to protection agai…
Deborah Kirkham
<h3>Introduction</h3> National tuberculosis (TB) HIV guidelines published in 2018<sup>1</sup> recommend latent TB testing with interferon gamma-release assay (IGRA) in at-risk populations. <h3>Methods</h3> The HIV department liaised with the TB department to develop a referral pr…
World Health Organization
This guideline provides updated WHO recommendations on HIV clinical management within a public health approach, focusing on optimization of antiretroviral therapy (ART), prevention of vertical HIV transmission and tuberculosis (TB) prevention among people living with HIV. It refl…
Kawatsu L, Kaneko N, Imahashi M, Kamada K, Uchimura K
…ues to be the leading cause of death for people living with HIV/AIDS (PLHIV), and HIV is the strongest known risk factor for progression to active TB disease for persons with latent TB infection (LTBI). Screening for active TB and LTBI, and TB preventive therapy (TPT) is recommen…
Rubina Bunjun, F. Millicent A. Omondi, Mohau S. Makatsa, Tracey L. Müller, Caryn S.L. Prentice, et al.
ABSTRACT HIV-1 infection substantially increases the risk of developing tuberculosis (TB). Some mechanisms, such as defects in the Th1 response to Mycobacterium tuberculosis ( M.tb ) in HIV-infected individuals have been widely reported. However, Th1-independent mechanisms also c…
Cui Z, Huang F, Liang D, Huang Y, Qin H, et al.
…ne the prevalence of TB among ambulatory people living with HIV in Guangxi Province, which experienced the biggest HIV epidemic in China. Methods We undertook a longitudinal study in five HIV/AIDS designated hospitals randomly selected from Guangxi Province; all newly diagnosed H…