Showing 126–150 of 200 documents
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Suzaan Marais, Fiona V Cresswell, Raph L Hamers, Lindsey H. M. te Brake, Ahmad Rizal Ganiem, et al.
<ns4:p> <ns4:bold>Background:</ns4:bold> Tuberculous meningitis (TBM), the most severe form of tuberculosis (TB), results in death or neurological disability in >50%, despite World Health Organisation recommended therapy. Current TBM regimen dosages are based on data from pulm…
Webster Chewe, Abidan Chansa, Patrick Lungu, Namakando Liusha
Extrapulmonary drug resistant tuberculosis (DR-TB) is a rare manifestation of disseminated tuberculosis which carries high mortality more so if the central nervous system (CNS) is affected. This paper reviews two cases of extrapulmonary DR-TB, involving two males both aged 32 yea…
Geng Ju Tuang, Athierah Muhammad, Farah Dayana Zahedi
The articles published in August 2020 entitled ‘tuberculosis (TB) or not TB?’ and ‘sarcoidosis with multiorgan involvement’ under the ‘image’ section have particularly caught our attention. The unfortunate occurrence of misdiagnosis of patients with TB infection, which has transp…
DR Gayathri Devi, Betu Rama Soujanya, Ashok Kumar Padmanabhan, SR Mangala Gouri, M Mahesh
Spinal Tuberculosis (TB) is the most common destructive form of extrapulmonary TB. The diagnosis of spinal TB is challenging involving combined approach of clinical diagnosis, imaging techniques, detection of acid-fast bacilli in microscopy, histopathology, and culture. This case…
D. Pavan, H. Ravish, S. Nagarathna, M. Nethravathi, K Sangeetha Seshagiri
Although tuberculosis (TB), caused by the bacteria Mycobacterium tuberculosis, affects the lungs in the majority of cases, it can also affect other parts of the body. It is most common in young children and HIV-infected patients, but it can also be found in adults with the condit…
Beijing Chest Hospital
…is the most lethal form of tuberculosis (TB). While anti-TB regimens remain the cornerstone of treatment, spinal injection of dexamethasone is considered a potentially effective adjuvant therapy. However, its impact on mortality and disability remains uncertain. This study analys…
M Ghanem, Hoda A. Makhlouf, AliAbdel-Azeem Hasan, DavidE S. Kelada
IntroductionThe prescription of effective and well-tolerated antituberculosis (TB) treatment regimen is an important step in the management of TB.ObjectiveTo compare the outcome of fixed-dose combination (FDC) therapy versus standard treatment (ST) in treatment of pulmonary tuber…
Amal Chakroun, Fatma Hammami, khaoula Rekik, Makram Koubaa, Fatma Smaoui, et al.
Abstract Background Tuberculous meningitis (TBM) is a life-threatening condition characterized by significant clinico-radiological heterogeneity. The challenges in achieving a definitive diagnosis, along with ongoing debates regarding treatment strategies, make it a complex condi…
Anuj Singhal, Sonal Singh, Arun Kumar Yadav, Amar Tej Atal, Shubham Shukla
Background: As per the World Health Organization Global Tuberculosis (TB) Report 2019, there were an estimated 10.0 million new TB cases worldwide in 2018, with India (27%) having the maximum burden of the disease. Drug-induced liver injury (DILI) due to antitubercular treatment …
Nisa Nur Tapaç, Ümmühan Çay, Fatma Kılınç, Selime Teleke Kaymaz, Özlem Özgür Gündeşli̇oğlu, et al.
Tuberculosis continues to be a significant global public health issue. Tuberculosis most often affects the lungs. However, children are more likely to have extrapulmonary involvement compared to adults. Ocular involvement is a rare extrapulmonary manifestation of tuberculosis. Oc…
Abdul Khalid Qadree, Sachin Mahendrakumar Chaudhary, Anasonye Emmanuel Kelechi, Sushmita Pandey, Sandesh Dhakal
Background: Tuberculous meningitis is a critical public health issue in underdeveloped nations due to its high morbidity and death. Tuberculous meningitis with non-specific symptoms of the central nervous system in children needs to be assessed with great vigilance as delay in di…
Megrelishvili Tamar, Ratiani Levan, Gaprindashvili Tinatin, Saralidze Nana, Nemsadze Grigol, et al.
Tuberculous meningitis is a severe manifestation of extrapulmonary tuberculosis, often associated with substantial morbidity and mortality. This case report discusses a unique presentation of tuberculous meningitis in a 39-year-old male who was concurrently positive for COVID-19.…
M Shahab, E Sturgill, O Okubadejo, T Persaud
Abstract Introduction Human immunodeficiency virus (HIV), particularly when progressing to acquired immunodeficiency syndrome (AIDS), renders individuals highly susceptible to opportunistic infections. Tuberculosis (TB) remains a leading cause of morbidity and mortality in HIV pa…
Zhaojing Zong, Yi Jian, Zhu Mei, Quanxian Liu, Liang Zhou, et al.
Abstract Purpose Tuberculosis meningitis is the most lethal type of tuberculosis, and its prognosis is related to disease severity and early therapeutic intervention. A model was developed to predict the mortality risk of adults with tuberculosis meningitis based on the prognosti…
Shital Patil, Swati Patil, Akshata Patil
Pleural effusion secondary to tuberculosis is second most common manifestation of extrapulmonary tuberculosis. Tuberculous pleural effusion is more frequently documented in India due to high TB burden setting and usually cured with universally available ATT as per NTEP program. V…
SM Ali Hasan, Nazmoul Hassan, Delwar Hossain, AKM Shafiqul Islam, Forhad Abedin, et al.
Background: Primary hepatic tuberculosis (PHT) is a rare form of extrapulmonary tuberculosis that affects the liver and is difficult to diagnose. The present case report describes a patient who was diagnosed with PHT and was successfully treated with a combination of anti-tubercu…
Sanchit Mohan, Nupoor Vaghasia, Vishwanath Pujari, Priti Meshram
Immune thrombocytopenia (ITP) is caused because of antibodies to platelets. ITP can be primary or secondary; secondary ITP is usually caused by infections. Tuberculosis (TB) is a rare cause of secondary ITP. Linezolid, despite being the backbone of a drug-resistant TB regimen, is…
Bella Devaleenal Daniel, Leeberk Raja Inbaraj, Shanmugapriya Kumaravadivelu, Kathirvel Subramanian, Balaji Ramraj, et al.
Tuberculous meningitis (TBM) disables more than a third of its sufferers. Recent research has focused on optimizing the antitubercular regimen, mainly by increasing the dosage of rifampicin. However, pyrazinamide, with higher penetration into the central nervous system, is genera…
Alejandro Rojas Urrea, Daniela Marino, Ana María Rojas-Faura, Mónica Liseth Holguín Barrera, Lorena García Agudelo
Tuberculosis is known as “the great mimicker.” Extrapulmonary tuberculosis accounts for approximately 20% of all cases, with about 10% of these involving the intestines. The ileocecal region is the most common site due to its high density of lymphoid tissue, slowed intestinal tra…
Héctor Mauricio Cárdenas Ramírez, Yaneya Acosta-Aguirre, David Zapata-Hernández, Susely Figueroa-Iglesias, Pedro Martínez‐Lozano, et al.
<b>Introduction:</b> Cervical tuberculous lymphadenitis (CTL) or scrofula is the most common extrapulmonary presentation of tuberculosis (TB), accounting for nearly 50% of the cases. This case report illustrates the role of artificial intelligence (AI)-based image ana…
Benaddi Mina, Abdelhafid Benksim, Fatihi Touria, S.A.B.O.U.R.A.L.A.O.U.I. Sanaa
Introduction:-Tuberculosis is a major public health issue in our country. Central nervous system tuberculosis has severe life threatening sequalae. The diagnosis of this form of tuberculosis is still challenging. Thus, availability of data about symptoms, paths of treatment, and …
Maja Kiselinova, Leslie Naesens, Diana Huis in ‘t Veld, Jerina Boelens, Eva Van Braeckel, et al.
Extrapulmonary nontuberculous mycobacterial (NTM) disease remains largely enigmatic, yet these mycobacteria are increasingly acknowledged as important opportunistic pathogens in humans. Traditionally, NTM infections have been identified across various anatomical locations, with t…
Rizvi I, Garg RK, Malhotra HS, Kumar N, Uniyal R
…eligible. The addition of aspirin to anti-tuberculosis drug regimens did not significantly reduce mortality [RR = 0.66 (0.42-1.02); low-quality evidence] but significantly reduced the risk of new infarctions [RR = 0.52 (0.29-0.92); moderate-quality evidence]. Aspirin did not diff…
Chhabra S, Kashyap A, Bhagat M, Mahajan R, Sethi S
Introduction Anemia is a common complication of pulmonary tuberculosis (TB). Nutritional deficiency and malabsorption syndrome can deepen the severity of anemia. The aim of the present study was to study anemia and nutritional status in patients with TB at a tertiary care center.…
Davis AG, Wasserman S, Stek C, Maxebengula M, Jason Liang C, et al.
Background Drug regimens that include intensified antibiotics alongside effective anti-inflammatory therapies may improve outcomes in tuberculous meningitis (TBM). Safety data on their use in combination and in the context of human immunodeficiency virus (HIV) are needed to infor…