Showing 126–150 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Laura Moretó Planas, MD
Tuberculosis (TB) diagnosis in children is challenging in low and middle-income countries where access to TB culture and X-ray is limited. More than half cases of childhood TB remain undiagnosed every year. A delay in TB diagnosis can lead to an increase in preventable morbidity …
Elfarissi MA, Dahamou M, Dehneh Y, Lhamlili M, Khoulali M, et al.
Background Pediatric sellar-suprasellar tuberculosis is a rare form of tuberculosis that affects the pituitary gland and surrounding areas in the brain. It can be difficult to diagnose based on clinical and radiological signs alone, as they can be similar to other pituitary masse…
Min Yu, Qi-Jun Jiang, Yuqing He, Fei Zhao, Tang-Ming Jin, et al.
Clinical manifestations of pediatric pulmonary tuberculosis (PTB) are atypical, making diagnosis challenging. This study aims to analyze the clinical characteristics of PTB to provide constructive suggestions for the diagnosis of PTB. A retrospective analysis was conducted on ped…
Marcy O, Goyet S, Borand L, Msellati P, Ung V, et al.
Background There is no gold standard for tuberculosis diagnosis in children. Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children were proposed by international experts in 2012 and updated in 2015. We aimed to compare the 2012 and 2015 Clinical C…
M.J. Cavaco, Sofia Giusti Alves, L. Mateus, André Nunes, Ricardo Cordeiro, et al.
<b>Introduction:</b> Early diagnosis of tuberculosis (TB) is essential to achieve cure and to reduce disease transmission. Total diagnostic delay (TDD) can be divided in patient delay (PD - from symptoms onset to seeking a health care facility) and health system delay (HSD - from…
Alexandra R Linn, Andrew P. Steenhoff
…ground The WHO currently estimates that at least a third of pediatric and adolescent tuberculosis cases go untreated or incompletely treated each year. Many cases are detected but lost to follow-up due to underreporting to national or private surveillance systems. Methods We cond…
Lo Vecchio A, Scarano SM, Amato C, Spagnuolo MI, Bruzzese E, et al.
The outbreak of COVID-19 resulted in a decrease in tuberculosis notification rates globally. We compared tuberculosis incidence rates and disease severity in children seen in our centre prior and during COVID-19 pandemic.We performed a cohort study enrolling children aged under 1…
Srabani Banerjee, Melissa Severn
Tuberculosis (TB) is one of the top 10 causes of death, worldwide. Worldwide 10 million people developed TB in 2017, (i.e.,133 cases per 100,000).– However, only 6.4 million cases were reported to WHO, indicating that 36% of cases were undiagnosed or not reported. According to a …
Patricia Comella-del-Barrio, José Luis Izquierdo-García, Ramón Campos‐Olivas, Clara M. Santiveri, Jesús Ruı́z-Cabello, et al.
Children’s paucibacillary tuberculosis (TB) and their difficulty to expectorate leads to low diagnostic sensitivity. Most TB in children are diagnosed by clinical scoring systems limited by the TB clinical presentation. Pediatric TB diagnosis research should be focused on new bio…
Ahang Hasan Mawlood
Background and objective: M. tuberculosis is one of the main causes of morbidity and mortality in many countries and is considered a priority global health problem. Although it is a curable disease, every year about nine million people develop active disease, and two million die …
Palmer M, Gunasekera KS, van der Zalm MM, Morrison J, Simon Schaaf H, et al.
…duction The chest radiograph (CR) remains a key tool in the diagnosis of pediatric tuberculosis (TB). In children with presumptive intrathoracic TB, we aimed to identify CR features that had high specificity for, and were strongly associated with, bacteriologically confirmed TB. …
Bayhan GI, Sayir F, Tanir G, Tuncer O
Background Pleural tuberculosis (TB) diagnosis is sometimes controversial because the microbiologic confirmation ratio is very low in pleural fluid. There are few pediatric pleural TB case series in the literature. Methods We retrospectively evaluated our TB cases below 18 years …
Agata Gierlotka, Ryszard Sordyl, Ireneusz Bielecki, Marek Mandera
… identify and evaluate the management options for pituitary tuberculosis in the pediatric population. **METHODS:** The study was conducted based on a comprehensive literature review using the PubMed, Cochrane Library, and ScienceDirect electronic databases. The following keyword…
Lucía Carratalà-Castro, Shilzia Munguambe, Belén Saavedra-Cervera, Petra de Haas, Alexander Kay, et al.
…ACKGROUND:** There has been a global pursuit to improve the diagnosis of tuberculosis in young children by applying diagnostic methods on accessible biospecimens such as stool. We aimed to conduct a systematic review on the accuracy of stool-based molecular tests for tuberculosis…
Spinal tuberculosis in pediatric patients is frequently associated with multiple vertebral lesions and could be complicated by kyphosis. The diagnosis should be confirmed by culturing or molecular–genetic study of the pathological tissues that are harvested from the zone of bone …
…ground The WHO currently estimates that at least a third of pediatric and adolescent tuberculosis cases go untreated or incompletely treated each year. Many cases are detected but lost to follow-up due to underreporting to national or private surveillance systems. Methods We cond…
Jyoti Sharma, Sanjeev Chaudhary, Sandesh Guleria, Vipan Garg, Anju Bala
…AAT) positivity in presumptive pulmonary and extrapulmonary tuberculosis (EPTB) in pediatric patients.Materials and methods: It was a descriptive observational study done in pediatric presumptive pulmonary tuberculosis (PTB) and EPTB patients in a tertiary care institute of north…
Muljadi R, Koesbandono, Octavius GS
Introduction Despite medical advancement, pediatric pulmonary tuberculosis (PTB) still has high morbidity and mortality, due to challenging detection in clinical practice. Ultrasound has been touted as the next best diagnostic tool but currently, this claim is unfounded. Therefor…
Taye K, Tolesa N, Tadewos A, Ketema W
…ckground Because of the pauci bacillary nature of childhood tuberculosis and the difficulties in obtaining proper sputum samples from young children, diagnosing childhood tuberculosis (TB) is difficult. Childhood TB needs early identification and care since it advances swiftly to…
James V, Samuel J, Ong GY
Background Tuberculosis of the abdomen is one of the most common extrapulmonary manifestations of tuberculosis. Even in areas where tuberculosis is endemic, intra-abdominal tuberculous can pose a diagnostic and management challenge because of the lack of presence of overt clinica…
Zainab Farooq, Hamza Sajid, Noor Un Nisa Irshad, Sakan Binte Imran
To the Editor, Pediatric TB is a significant global public health issue, with accurate diagnosis being a primary barrier to finding and treating afflicted children. According to WHO Global Tuberculosis Report 2024, an estimated 10.8 million people were diagnosed with TB worldwide…
Matthew Willis, Joelle Van de Wetering, Heynes Brown, Ewelina Julia Barnowska, Sophie Cw Stuetzle, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) is a significant public health concern in India, contributing to 28% of the global pediatric TB burden. Despite its impact on child health, strategies to control TB have inadequately addressed pediatric cases, resulting in suboptimal ma…
Çakır E, Özdemir A, Daşkaya H, Umutoğlu T, Yüksel M
…e, gastric aspirate and bronchoalveolar lavage fluid in the diagnosis of childhood tuberculosis. Turk J Pediatr 2018; 60: 10-13. Pulmonary tuberculosis (TB) is an important cause of morbidity and mortality especially in developing countries. A definitive microbiologic confirmatio…
Shu‐Han Yu
As a new immunoassay, T-SPOT.TB has been widely used in the diagnosis of tuberculosis in children.A large number of clinical trials show that it has better sensitivity and specificity simultaneously, compared with other diagnostic methods for tuberculosis in children.This article…
Mase A, Ryan S, Mader G, Alvarez A, Armitige L, et al.
…or Disease Control and Prevention (CDC) funds five Regional Tuberculosis Training and Medical Consultation Centers (RTMCCs) that provide training and consultation for tuberculosis (TB) control and management. RTMCC utilization for assistance with diagnosis and management of TB in…