Showing 126–150 of 200 documents
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Rebecca F. Baggaley, Carolin Vegvari, Christian Akem Dimala, Marc Lipman, Robert F. Miller, et al.
…untries (<100 cases/100,000/year), screening and preventive treatment (PT) for latent TB infection (LTBI) among people living with HIV (PLWH) is often recommended, yet guidelines advising which groups to prioritise for screening can be contradictory and implementation patchy. Evi…
Anggi Angelia, Diana V. D. Doda, Aaltje E. Manampiring
… Quantitative research aimed to determine the prevalence of latent tuberculosis among healthcare workers, evaluate preventive measures, and compliance to use PPE among healthcare workers. The objective of the qualitative research was to evaluate management policies and barriers t…
Ford N, Maher D, Rangaka MX, Baddeley A, Singh S, et al.
Purpose of review Guidelines developed by the WHO aim to provide recommendations to support best practice in health delivery, with a focus on low-income and middle-income countries. As part of the guideline development process, critical knowledge gaps are identified and one of th…
Chaisson R
…tion tuberculosis in individuals infected with both HIV and latent (inactive) Mycobacterium tuberculosis. Current guidelines from the American Thoracic Society and the Centers for Disease Control recommend 6 to 12 months of INH for PPD (purified protein derivative)-positive indi…
Swain S, Kumar A, Vishwakarma VK, Aayilliath K A, Mittal A, et al.
…and around 18-36 lakh develop active tuberculosis annually. Latent TB is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence of clinically manifested active TB. The progression of a latent infection to active tub…
Yu Chen, Yaguo Wang, Joy Fleming, Yanhong Yu, Ye Gu, et al.
…with M. tuberculosis (MTB), the pathogen that causes TB and latently infects ∼25% of the global population, may be a risk factor for SARS-CoV-2 infection and severe COVID-19 pneumonia. Objective To determine if latent or active TB increase susceptibility to SARS-COV-19 infection …
Alzahabi KH, Usmani O, Georgiou TK, Ryan MP, Robertson BD, et al.
…sulting with a mortality approximating 1.5 million. Current treatment guidelines recommend oral administration of a combination of first-line anti-TB drugs for at least 6 months. While efficacious under optimum conditions, 'Directly Observed Therapy Short-course' (DOTS) is not wi…
Faust L, Ruhwald M, Schumacher S, Pai M
… aims Despite the World Health Organization (WHO)'s updated guidelines on tuberculosis (TB) preventive treatment, the scale-up of TB preventive therapy remains low in many high-burden countries (HBCs). We conducted a survey to better understand the current status of policy implem…
Hargreaves S, Nellums LB, Johnson C, Goldberg J, Pantelidis P, et al.
Background Screening for latent tuberculosis infection (LTBI) in migrants is important for elimination of tuberculosis in low-incidence countries, alongside the need to detect blood-borne infections to align with new guidelines on migrant screening for multiple infections in Euro…
Phani V Akella, Rachel Sigler
…ent AMR and Grade 1R acute cellular rejection (ACR) needing treatment with plasmapheresis, intravenous immunoglobulin (IVIG) and steroids. About three weeks post OHT, she developed fever, lactic acidosis, and hypotension. Infectious workup including blood cultures, respiratory pa…
Migliori GB, Tiberi S, Tiberi S, Zumla A, Petersen E, et al.
…ntinuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from con…
Wyndham-Thomas C, Dirix V, Goffard JC, Henrard S, Wanlin M, et al.
…jectives : To review the current knowledge on screening for latent tuberculosis infection (LTBI) in HIV-infected adults and provide specific guidelines for Belgium. Focus is given to who to test, which testing method to use, timing of screening and choice of LTBI treatment. Metho…
Brett K, Severn M
…ency in the majority (i.e., around 95%) of people, known as latent TB infection. People with latent TB do not have any symptoms, and cannot spread the TB infection to others, however, they can develop active TB disease., Active TB disease occurs when the TB bacteria overwhelm the…
Joseph A Kovacs, M.D.
…HIV also have the lung infection tuberculosis (TB). Most TB treatments are complicated. A simpler treatment of two TB drugs can be taken once a week. Researchers want to study how the HIV and TB drugs affect each other so people who take both can be treated safely. Objective: T…
Starke SJ, Martinez Rivera MB, Krishnan S, Shah M
…take on an expanded role in the diagnosis and management of latent tuberculosis infection (LTBI). Clinical practice guidelines and recommendations exist for LTBI management, but there is a need for innovative tools to improve medical students' and residents' knowledge of evidence…
Kendra Brett, Melissa Severn
…ency in the majority (i.e., around 95%) of people, known as latent TB infection. People with latent TB do not have any symptoms, and cannot spread the TB infection to others, however, they can develop active TB disease., Active TB disease occurs when the TB bacteria overwhelm the…
Lana Fadl, Arowa Abdelgadir, Hendy Mirza, Aqsa Mahreen, Siddalingana Gouda
…cept, golimumab, and infliximab—are recommended for severe, treatment-resistant AS. Adalimumab, a monoclonal anti-TNF-α antibody, has been linked to a higher tuberculosis (TB) risk than etanercept, with literature suggesting a three- to fourfold increase. We present a rare case o…
Occhineri S, Matucci T, Rindi L, Tiseo G, Falcone M, et al.
…d Health Organization (WHO) determined to include PA in its guidelines for the treatment of rifampicin-resistant (RR), multi drug resistant (MDR) and pre-extensively drug resistant TB (pre-XDR-TB) with BDQ, LZD and Moxifloxacine (MFX) in a 6-month regimen. Although further studie…
María Elvira Balcells, MD; MSc
…exposure within the household, during the first weeks of TB treatment initiation of the index case, can reduce new TB infections in close contacts. For this purpose, a pilot, controlled, pre-post study will be set up, to evaluate the feasibility of implementing a bundle of respir…
Gröschel MI, van den Boom M, Migliori GB, Dara M
… the existing World Health Organization (WHO) documents and guidelines on childhood and adolescent TB and describe the outcomes of this regional meeting. National childhood and adolescent TB guidelines are available in 25% of Member States, while 33% reported that no such guideli…
Yu Bai, Y. Xue, Mucong Li, Mengtao Li, Chanyuan Wu
…rom approximately 1.2 to over 5, depending on disease type, treatment exposure, and regional TB burden.[3,4] Beyond absolute prevalence, longitudinal data further highlight the sustained and cumulative risk of TB over time in RMD cohorts. Population-based studies from Sweden have…
Friedman A, DeGeorge KC
… demonstrated minimal clinical improvement after initiating treatment for COVID-19, further investigations uncovered concomitant reactivated TB. This case is helpful in underscoring the potential implications of the COVID-19 pandemic and current treatment guidelines on the global…
Gisele Meinerz, Cynthia Keitel da Silva, Damaris Mikaela Balin Dorsdt, Julia Bertoni Adames, Julio Pasquali Andrade, et al.
… infectious complication after kidney transplantation (KT). Latent tuberculosis infection (LTI) screening and treatment is fundamental to prevent post-transplant active disease. Methods: We described a cohort of adult KT recipients from April 4th, 2014 to October 31st, 2018, with…
Jyoti S. Mathad, MD, MSc
…ted and HIV-1-uninfected pregnant and postpartum women with latent tuberculosis (TB). TB is a major cause of illness and death in women of reproductive age. Pregnant and postpartum women with latent TB are at higher risk of developing active TB. This study evaluated the pharmaco…
Joseph Sturman, Jyoti Baharani, Jed Ashman, Lorraine Harper, Adam F Cunningham, et al.
…tion in endemic countries. Patients with CKD generally have latent TB reactivation, rather thaninfection, which presents with atypical, non-pulmonary presentations leading to late diagnosis, poorer outcomes and a high risk of widespread transmission through haemodialysis units. T…