Showing 126–150 of 200 documents
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Saini S, Prasad BM, Mahajan A, Duhan A, Jangra A, et al.
…from implementation indicate the need to strengthen private diagnostics through a certification process to ensure provision of quality TB diagnostic services.
Xiaoting Liu, Dong XiLin, Yu Zhang, Ping Fang, Hongyang Shi, et al.
Abstract Background: Pleural effusions are caused by various reasons, whose diagnosis remains challenging in spite of various means of diagnosis. Medical thoracoscopy, greatly improves the diagnostic efficacy and gets preference for managements, especially undiagnosed pleural eff…
Hamid Dahmardeh, Alireza Teimouri, Zeynab Shayan Khah
Background: Pulmonary tuberculosis (PTB) remains a major global health concern that requires early and accurate diagnosis. Standard methods, such as sputum smear microscopy and culture, are often slow and may miss smear-negative cases. Chest computed tomography (CT) can reveal ra…
Banerjee R, Pal P, Girish BG, Reddy DN
Background The diagnosis of Crohn's disease (CD) can be delayed in clinical practice. In tuberculosis endemic areas, empirical anti-tubercular therapy further delays treatment. Aim(s) To assess risk factors for diagnostic delay and its impact on the long-term complications of Cro…
Yerlikaya S, Holtgrewe LM, Broger T, Isaacs C, Nahid P, et al.
…ty target product profiles (TPPs) for new tuberculosis (TB) diagnostics to align end-user needs with test targets and specifications; nevertheless, no TB test meets these targets to date. The COVID-19-driven momentum in the diagnostics world offers an opportunity to address the l…
MH Mezzour, M. Karhate, L. Senhaji, M. Taghyioullah, B. Amara, et al.
Abstract RATIONALE: Pseudotumoral tuberculosis (TB), an uncommon malignancy-mimicking form of pulmonary TB, often causes diagnostic delays, especially in patients without TB history or immunosuppression. In TB-endemic areas, reliance on negative sputum culture or GeneXpert result…
Bjørn Waagsbø, Eva Margrethe Buset, Jørn-Åge Longva, Merete Bjerke, Birgitte Bakkene, et al.
PURPOSE: Studies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, retrospective, regional study from Norway, our primary object…
Qu H, Wang M, Wang Z, Ao G, Yuan X, et al.
Rationale and objectives This prospective study aimed to evaluate the diagnostic performance of dual-input computed tomography perfusion technique (DI-CTP) in identifying the bronchial-pulmonary artery fistula in patients tuberculosis with massive hemoptysis. Material and methods…
Limsrivilai J, Pausawasdi N
Differentiating Crohn's disease (CD) from intestinal tuberculosis (ITB) is a diagnostic dilemma, particularly in regions where ITB is prevalent and CD incidence is increasing, because both diseases can present quite similarly, and diagnostic tests to identify Mycobacterium tuberc…
Rina Triasih
In general, the diagnosis of COVID-19 in children is the same as that in adults, which is based on the clinical and epidemiological history of the patient. Clinicians should have a suspicion of COVID-19 when a child shows one or more clinical manifestations of COVID-19 and, withi…
Dimitri Daraselia, Ani Toloraia, Salome Tsertsvadze, Marika Todua
…elay. These cases highlight the limitations of conventional diagnostics in both pulmonary and pleural TB, particularly in smear- and polymerase chain reaction (PCR)-negative presentations. They underscore the importance of clinical vigilance and timely escalation to tissue-based …
Peerzada Ajaz A Shah, Mustafa Bashir, Moien Farooq, Tavseef A Tali, Toufeeq A Teli
**BACKGROUND:** Exudative pleural effusion is a common clinical problem with diverse etiologies, often requiring invasive procedures for definitive diagnosis. While conventional cytology is widely used, its diagnostic yield remains limited. Ancillary methods such as cell block (C…
Zhang Y, Zhan B, Hao X, Wang W, Zhang X, et al.
Purpose Tuberculosis is a high-burden disease and a major health concern in China, especially among children and adolescents. The purpose of this study was to assess risk factors for diagnostic delay in students with pulmonary tuberculosis in Quzhou City in eastern China. Patient…
Yadav D, Garg RK, Chhabra D, Yadav R, Kumar A, et al.
…resent work illustrates the promising intervention of smart diagnostics devices through artificial intelligence (AI) and mechanobiological approaches in health care practices. The artificial intelligence and mechanobiological approaches in diagnostics widen the scope for point of…
Hangxing Wang, Yuanchun Li, Lifan Zhang, Xiaoqing Liu
**BACKGROUND AND OBJECTIVES:** Patients with rheumatic immune diseases (RD) are considered a high-risk population for developing active tuberculosis (ATB). Timely and accurate diagnosis of ATB in RD patients is critical for optimizing treatment outcomes and improving prognosis. B…
Cherian SV, Kaur S, Karanth S, Xian JZ, Estrada-Y-Martin RM
Introduction Electromagnetic navigational bronchoscopy (ENB) is an excellent tool to diagnose peripheral pulmonary nodules, especially in the setting of emphysema and pulmonary fibrosis. However, most of these procedures are done by interventional pulmonologists and academic tert…
Xuxiang Song, Qipan Zhang, Tiantian Cen, Wei Fan, Weili Chen, et al.
**OBJECTIVE:** This study aimed to assess Interleukin-39 (IL-39) levels in various types of pleural effusion (PE), explore IL-39's diagnostic value in tuberculous pleurisy, analyze its correlation with other PE and tuberculosis indicators, and confirm the involvement of IL-39 in …
Engel N
…ted in global innovation practices for tuberculosis and HIV diagnostics, and to what effect. It examines the development of point-of-care (POC) diagnostics - promised to be designed for users outside laboratories or in resource constrained settings - to study what developers and …
Pape S, Gulma K, Shivalli S, Cleenewerck de Kiev L
Individuals entering incarceration are at high risk for infectious diseases, other ill conditions, and risky behavior. Typically, the status of active pulmonary tuberculosis (PTB) is not known at the time of admission. Early detection and treatment are essential for effective TB …
Di Gennaro F, Cotugno S, Guido G, Cavallin F, Pisaturo M, et al.
Background Tuberculosis (TB) remains a Global Health challenge, with diagnostic delays contributing significantly to its spread. This study investigates the differences in diagnostic delays between native and migrant TB patients in Italy, examining patient-related diagnostic dela…
Khambati N, Song R, MacLean EL, Kohli M, Olbrich L, et al.
Background Tuberculosis (TB) is a leading cause of death in children, but many cases are never diagnosed. Microbiological diagnosis of pulmonary TB is challenging in young children who cannot spontaneously expectorate sputum. Nasopharyngeal aspirates (NPA) may be more easily coll…
Qanash S, Hakami OA, Al-Husayni F, Gari AG
Objective Flexible fiberoptic bronchoscopy (FFB) has become an essential procedure for diagnosing and managing various respiratory conditions. We aimed to assess the main indications, diagnostic yield, and safety of FFB in our institute. Methods A total of 216 patients who underw…
Lucy Mupfumi, Tapson Nyondo, Judith Mzyece, Vincent Kampira, Moussa Condé, et al.
…eaching universal access to WHO-recommended rapid molecular diagnostics (WRDs) in a selection of African countries. Data for 24 African countries were sourced from the WHO Global TB database to evaluate the proportion of notified people with TB tested with a WRD between 2018 and …
Peng L, Dai L, Zhu M, Fang T, Sun H, et al.
Objectives The diagnosis of tuberculosis pleural effusion (TPE) remains challenging, traditional diagnostic tests have limited diagnostic efficacy. This study aimed to assess the diagnostic performance of pleural fluid (PF) lipoarabinomannan (LAM) in TPE. Methods A diagnostic met…
Zhang J, Chen J, Zhang Y, Chen L, Mo W, et al.
…pathogen-based diagnoses and the inability of immunological diagnostics to detect active TB. Hence, it is urgent to develop new techniques to detect TB more accurate and earlier. This research aims to scrutinize and authenticate DNA methylation markers suitable for tuberculosis d…