Showing 126–150 of 200 documents
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Consejo Ejecutivo, 126
Takele Teklu, Biniam Wondale, Biruhalem Taye, Milkessa Hailemariam, Shiferaw Bekele, et al.
Additional file 4: Supplemental dataset S4. Independent-sample t-tests to identify proteins that were up-regulated or down-regulated upon stimulation with the ESAT-6/CFP-10 antigen cocktail. Fifty-nine proteins were significantly regulated upon stimulation with the ESAT-6/CFP-10 …
Asamblea Mundial de la Salud, 63
Khader Y, Al-Rahamneh MJ, Abu Khudair S, Abaza H, Al Shatnawi A, et al.
Objectives Evaluate and determine the gaps in the National Tuberculosis Program and Tuberculosis Surveillance System in Jordan. Methods A concurrent embedded mixed quantitative/qualitative methods study was conducted to assess the National Tuberculosis Program and Tuberculosis Su…
Bhargava A, Bhargava M, Meher A, Benedetti A, Velayutham B, et al.
Background In India, tuberculosis and undernutrition are syndemics with a high burden of tuberculosis coexisting with a high burden of undernutrition in patients and in the population. The aim of this study was to determine the effect of nutritional supplementation on tuberculosi…
V. S. Krutko, L. H. Nikolaieva, Tetiana Maistat, О.A. Oparin, Anton Rohozhyn
Tuberculosis is infectious and socially dependent disease, being now one of the most pressing issues in practical health care. As well the usual types of tuberculosis infection, chemoresistant tuberculosis is spreading rapidly in the world. The WHO estimates that about 500,000 pe…
O.I. Sakhelashvili–Bil
Objective — to study the features of multidrug-resistant tuberculosis of the lungs of respiratory organs in children and adolescents from focuses of chemoresistant tuberculosis infection. 
 Materials and methods. To study the features of the course of multidrug-resistant pul…
A.R. Aroyan, А. В. Мордык
Introduction . Extrapulmonary tuberculosis is more difficult to diagnose than respiratory tuberculosis. However, late detection leads to disabling consequences. Children from 4 to 11 years old are at risk for tuberculosis due to increased communication skills. It seems relevant t…
Zifodya JS, Kreniske JS, Schiller I, Kohli M, Dendukuri N, et al.
…on (WHO)-recommended rapid tests that simultaneously detect tuberculosis and rifampicin resistance in people with signs and symptoms of tuberculosis. This review builds on our recent extensive Cochrane Review of Xpert MTB/RIF accuracy. Objectives To compare the diagnostic accurac…
Prabha Desikan, Aseem Rangnekar, Nikita Panwalkar, Ram Prakash Punde, Sridhar Anand
…etection and treatment of drug resistance in extrapulmonary tuberculosis (EPTB) is a major challenge worldwide. Drug resistance in EPTB has not been studied extensively. However, patients with drug-resistant EPTB have been reported to have poor outcomes[1]. Rifampicin and isoniaz…
Ahmad al Jbawi, Mohammad Fadel, Fares Kahal, Michel Najjar, Sara Albuaini, et al.
Abstract Background : Tuberculosis (TB) is a major public health concern worldwide and is the 13th leading cause of death and the second deadliest infectious disease after COVID-19. ¹ Extrapulmonary tuberculosis (EPTB) cases accounted for 16% of the 7.5 million cases of TB worldw…
Van Hoving DJ, Griesel R, Meintjes G, Takwoingi Y, Maartens G, et al.
Background Accurate diagnosis of tuberculosis in people living with HIV is difficult. HIV-positive individuals have higher rates of extrapulmonary tuberculosis and the diagnosis of tuberculosis is often limited to imaging results. Ultrasound is such an imaging test that is widely…
Ravindra Y Mandolikar, Raju Hanumant Patil, Narendra Madhekar
Introduction: Tuberculosis is a chronic, communicable, infectious disease caused by Mycobacterium tuberculosis bacilli usually affecting lungs primarily resulting in pulmonary tuberculosis. Objective: to evaluate the Revised National Tuberculosis Control Programme (RNTCP) through…
Simon C Mendelsohn, Humphrey Mulenga, Michele Tameris, Tumelo Moloantoa, Stephanus T Malherbe, et al.
**BACKGROUND:** More than half of tuberculosis cases detected by community prevalence surveys are classified as asymptomatic. We evaluated yield of symptom and chest radiograph screening of tuberculosis-exposed household contacts in South Africa. **METHODS:** For this prospectiv…
Berrocal-Almanza LC, Harris R, Lalor MK, Muzyamba MC, Were J, et al.
… Evaluating interventions that might lead to a reduction in tuberculosis in high-income countries with a low incidence of the disease is key to accelerate progress towards its elimination. In such countries, migrants are known to contribute a large proportion of tuberculosis case…
Menzies NA, Quaife M, Allwood BW, Byrne AL, Coussens AK, et al.
Background Many individuals who survive tuberculosis disease face ongoing disability and elevated mortality risks. However, the impact of post-tuberculosis sequelae is generally omitted from policy analyses and disease burden estimates. We therefore estimated the global burden of…
Nilesh NamdeoGhule, Geeta Shiroor
The high incidence of Tuberculosis is a cause for concern and a huge threat to public health globally. The delays in case detection, diagnosis, health seeking, and non-adherence to treatment are some of the reason for the high Tuberculosis burden globally. In many tuberculosis Ce…
Melike Hazal Can, Sedona Sweeney, Brian W Allwood, Susan E Dorman, Ted Cohen, et al.
**BACKGROUND:** Untreated pulmonary tuberculosis causes ongoing lung damage, which can persist after treatment. Conventional modelling approaches for assessing tuberculosis health effects might not fully capture these mechanisms. We evaluated how tuberculosis-associated lung dama…
Ogwang MO, Imbuga M, Ngugi C, Mutharia L, Magoma G, et al.
Introduction Globally anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis. Kenya is ranked among 30 high burden TB countries globally. However, there is scanty information on second line antituberculosis drug resistanc…
Kim JW, Bowman K, Nazareth J, Lee J, Woltmann G, et al.
Background Incipient tuberculosis, a progressive state of Mycobacterium tuberculosis infection with an increased risk of developing into tuberculosis disease, remains poorly characterised. Animal models suggest an association of progressive infection with bacteraemia. Circulating…
da Costa FBP, Nicol MP, Botha M, Workman L, Arcêncio RA, et al.
Background Paediatric tuberculosis leads to more than 200 000 deaths annually. We aimed to investigate the incidence of Mycobacterium tuberculosis infection and tuberculosis disease in the first decade of life in the Drakenstein Child Health Study (DCHS), a South African cohort i…
Fernanda Bruzadelli Paulino da Costa, Mark P. Nicol, Maresa Botha, Lesley Workman, Ricardo Alexandre Arcêncio, et al.
BACKGROUND: Paediatric tuberculosis leads to more than 200 000 deaths annually. We aimed to investigate the incidence of Mycobacterium tuberculosis infection and tuberculosis disease in the first decade of life in the Drakenstein Child Health Study (DCHS), a South African cohort …
Leonardo Martínez, Neus Altet, F Boulahbal, Joan A. Caylà, Tsira Chakhaia, et al.
…t Objective To evaluate the impact of isoniazid on incident tuberculosis in household contacts of MDR tuberculosis cases. Design Systematic review and individual-participant meta-analysis. Data sources MEDLINE, Web of Science, BIOSIS, and Embase without language restrictions for …
Marcy O, Goyet S, Borand L, Msellati P, Ung V, et al.
Background There is no gold standard for tuberculosis diagnosis in children. Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children were proposed by international experts in 2012 and updated in 2015. We aimed to compare the 2012 and 2015 Clinical C…
Saunders MJ, Wingfield T, Datta S, Montoya R, Ramos E, et al.
…eness of social protection and biomedical interventions for tuberculosis-affected households might be improved by risk stratification. We therefore derived and externally validated a household-level risk score to predict tuberculosis among contacts of patients with tuberculosis. …