Showing 101–125 of 200 documents
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Abayneh M, Teressa M
…istently deciding its current extent and chance elements of tuberculosis (TB) in all levels of clinical settings contributes to the anticipation and control exertion of the disease. In Ethiopia, updated information is still needed at every healthcare level and in different risk g…
Selim A, Elhaig MM, Taha SA, Nasr EA
Tuberculosis (TB) is an endemic disease in animals and humans in Egypt. This study aims to investigate the antimycobacterial activity of silver nanoparticles(AgNPs) by determining the minimal inhibitory concentration (MIC) of AgNPs, using the microplate Alamar blue assay. The AgN…
Oyedeji GJ, Adeyemo C, Dissou A, Abiodun T, Alli OAT, et al.
Background The development of multidrug-resistant tuberculosis (MDR-TB) poses a considerable threat to tuberculosis control programmes in Nigeria. There is an increase in the prevalence of MDR-TB worldwide both among new tuberculosis cases as well as previously-treated ones. Ther…
Hameed S, Mahmood N, Chaudhry MN, Ahmad SR, Rahman MA
…alence of drug resistance it is necessary to diagnose TB in tuberculosis sputum suspect patients instead of TB-cultured samples which required a long time of culturing. Comparison of the results of drug resistant bacterial genes in both tuberculosis suspect sputum and multi-drug …
Sushma Yadav, Surya Kant, Amita Jain, Rashmi Ratnam
<bold>Title:</bold> Linezolid-resistant Mycobacterium Tuberculosis: a highly concerning situation for the tuberculosis eradication program. <bold>Objective:</bold> · Identification of drug sensitivity in Multi Drug Resistant tuberculosis culture isolates <bold>Method:</bold> The …
Alireza Jafari, Raj Goswami, Hesamaddin Shirzad‐Aski, Nasser Behnampour, Masoomeh Taziki, et al.
Background: Tuberculosis is appraised to cause the deaths of more than a billion people in the last decades. Objectives: The current study compares the performance of microplate Alamar blue assay for clinical isolates of Mycobacterium tuberculosis and multidrug-resistant tubercul…
José Wellington Macêdo Viana, Rodolfo Pinheiro Torres
Tuberculosis (TB) is a chronic and serious infectious disease caused by Mycobacterium tuberculosis that mainly affects the lungs, but it is also capable of infecting other organs/tissues in the body, which triggers extra-pulmonary TB. In recent years, there has been an increase i…
World Health Organization
…ex to the second edition of the WHO operational handbook on tuberculosis, Module 1: Prevention – tuberculosis preventive treatment, presents pharmacokinetic modelling and simulation studies used to inform dosing recommendations for levofloxacin preventive therapy (6Lfx) and the 3…
Somphavong S, Berland JL, Gauthier M, Vu TT, Nguyen QH, et al.
Background In Lao People's Democratic Republic (PDR), tuberculosis (TB) prevalence was estimated at 540/100,000 in 2011. Nevertheless, little is known about the genetic characteristics and anti-TB drug resistance of the Mycobacterium tuberculosis population. The main objective of…
Vilchèze C, Kim J, Jacobs WR Jr
The treatment of drug-susceptible tuberculosis (TB) is long and cumbersome. Mismanagement of TB treatment can lead to the emergence of drug resistance in patients, so shortening the treatment duration could significantly improve TB chemotherapy and prevent the development of drug…
Herin Mawarti, Mukhamad Rajin, Zulfa Khusniyah, Zulfikar Asumta, Khotimah, et al.
…, especially in multidrug resistant strain of Mycobacterium tuberculosis, has not been evaluated yet. This study aims to determine the potential of Aloe vera as an antituberculosis against drug-resistant strains of tuberculosis. Method: Stages of research include the production o…
Asnake Simieneh, Rahel Dereje, Tadesse Misganaw, Gossa Fetene Abebe
Multidrug-resistant tuberculosis (MDR-TB) is increasingly recognized as a global public health challenge. Continuous monitoring of the prevalence of MDR-TB and its associated factors is crucial for the effective control and management of this disease. While alarming rates of MDR-…
Xiaoqin Xiong, Fangfang Zhong
…sess the global, regional, and national burden of pulmonary tuberculosis (TB), including drug-susceptible (DS-TB) and multidrug-resistant TB (MDR-TB), among children and adolescents from 1990 to 2021, and to project trends to 2045. **METHODS:** Data were extracted from the Globa…
Mahfuza Talukder Flowra, MSc. Yodi Mahendradhata, Mph Ari Probandari
Background: Multi-drug-resistant Tuberculosis (MDR-TB) is one of the emerging and global crises worldwide. Though global prevalence and incidence of TB is in declining mode; Bangladesh is still in the list of 30 high Tuberculosis (TB) burden countries. Even having successful DOTs…
Elduma AH, Holakouie-Naieni K, Almasi-Hashiani A, Rahimi Foroushani A, Mustafa Hamdan Ali H, et al.
…ble robust method to estimate the causal effect of previous tuberculosis treatment history on the occurrence of multidrug-resistant tuberculosis (MDR-TB). TMLE is a method to estimate the marginal statistical parameters in case-control study design. The aim of this study was to e…
М. В. Павлова, Tatiana Vinogradova, Natalia Zabolotnykh, Elena Ershova, Н. В. Сапожникова, et al.
…y of increasing of the efficiency of therapy of respiratory tuberculosis with drug resistant pathogen by including a combination of anti-tuberculosis drugs of new generation Bedaquiline (Bq) and Thioureidoiminomethylpyridi-nium perchlorate (perchlozone, Tpp) into treatment regime…
World Health Organization
…mpanying the 2022 update of the WHO operational handbook on tuberculosis, Module 4: treatment – drug-resistant tuberculosis treatment. The document provides detailed technical information to support implementation of WHO recommendations for the management of drug-resistant tuberc…
World Health Organization
…nal handbook complements the WHO consolidated guidelines on tuberculosis by providing practical guidance for the treatment and programmatic management of drug-resistant tuberculosis (DR-TB), including multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB) and rifampicin-susc…
Soesanti Soesanti, Abd Hakim Husen
Tuberculosis (TB) is one of the top 10 causes of death worldwide. Multidrug Resistant Tuberculosis (MDR-TB) is TB that is drug resistant to at least 2 (two) most potent anti-TB drugs. This study aims to determine the relationship between age and sex factors with the incidence of …
Michel Kiréopori Gomgnimbou, Dinanibè Kambiré, Saïdou Jean Eudes Paré, Louis Robert W. Belem, Léon T. Sawadogo, et al.
Multidrug-resistant tuberculosis (MDR-TB) is a major public health problem worldwide, particularly in Eastern Europe, Russia, and Sub-Saharan Africa due to its prevalence, burden, treatment management difficulties, and socio-economic impacts. Burkina Faso is also facing the chall…
World Health Organization
… to the third edition of the WHO consolidated guidelines on tuberculosis, Module 3: diagnosis, presents Grading of Recommendations Assessment, Development and Evaluation (GRADE) profiles for rapid diagnostic technologies used in tuberculosis detection and drug-resistance testing.…
World Health Organization
…ies the third edition of the WHO consolidated guidelines on tuberculosis, Module 3: diagnosis – rapid diagnostics for tuberculosis detection. The publication provides comprehensive lists of studies included in the systematic reviews that informed WHO recommendations on rapid diag…
…tion of the first United Nations (UN) high-level meeting on tuberculosis (TB) calls countries to diagnose and treat 40 million people with TB globally between 2018 and 2022. Traditionally, in most countries, TB diagnosis has been performed using sputum-smear microscopy, a method …
Bangarwa M, Dhingra D, Mittal M, Saigal K, Ghosh A
…world with almost 27 lakh cases reported in 2019. Pediatric tuberculosis in India accounts for almost 31% of global TB burden. Despite such high mortality and morbidity in children, diagnosis of pulmonary TB in children still remains very challenging. Material and methods This cr…
Esteves LS, Dalla Costa ER, Vasconcellos SEG, Vargas A, Ferreira Junior SLM, et al.
Tuberculosis (TB) remains a major public health problem in the world and Brazil is among the countries with the highest incidence and prevalence rates, and Rio Grande do Sul, a Brazilian state, occupy a prominent position. Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) f…