Showing 76–100 of 200 documents
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Şua Sümer, Nazlım Aktuğ Demir, Onur Ural, Fatma Çölkesen
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis that can affect all organs and tissues. The clinical forms of primary cutaneous tuberculosis are tuberculosis primary complex (tuberculosis chancre) and tuberculosis cutis miliaris (miliary cutaneous tuber…
Raju Hanumant Patil, Ravindra Y Mandolikar, Narendra Madhekar
Background: Tuberculosis is a very ancient disease of mankind; its description has been found in Hippocrates (460-377BC) observation, the ancient Buddhist and Chinese writing. Objective: To evaluate the RNTCP through assessment of treatment outcome of the pulmonary tuberculosis p…
Niladrita Deb -
…A study to assess the effectiveness of STP on prevention of tuberculosis among care takers of patients with tuberculosis visited at selected hospital of Kanpur. The objective of the study was to assess the pretest and post - test level of knowledge regarding prevention of tubercu…
Phe Tran Thi, Quyen Bui Thi Tu, Hoa Nguyen Binh
…d: The study aims to describe the knowledge and practice of tuberculosis prevention among family members of pulmonary tuberculosis patients being treated at Da Nang Lung Hospital in 2023 and some associated factors. Methods: A cross-sectional study was conducted on 168 family mem…
Meier NR, Sutter TM, Jacobsen M, Ottenhoff THM, Vogt JE, et al.
Rationale Tuberculosis diagnosis in children remains challenging. Microbiological confirmation of tuberculosis disease is often lacking, and standard immunodiagnostic including the tuberculin skin test and interferon- γ release assay for tuberculosis infection has limited sensiti…
Chandulal, Rohan Naik
Tuberculosis is the major public health concern globally. Cardiovascular involvement was observed in 1-2% of cases with pulmonary tuberculosis. The present study was designed to assess the ECG changes in pulmonary tuberculosis before and after anti-tuberculosis therapy. A total o…
Chiang SS, Murray MB, Kay AW, Dodd PJ
Introduction During adolescence, tuberculosis incidence rises, with a greater increase in males compared with females. Tuberculosis notifications and estimates infrequently disaggregate adolescent age groups. Moreover, the factors that drive the increases in overall incidence and…
Reichler MR, Khan A, Sterling TR, Zhao H, Moran J, et al.
Background The risk and timing of tuberculosis among recently exposed close contacts of patients with infectious tuberculosis are not well established. Methods We prospectively enrolled patients ≥15 years of age with culture-confirmed pulmonary tuberculosis and their close contac…
Silva S, Arinaminpathy N, Atun R, Goosby E, Reid M
Background The tuberculosis targets for the UN Sustainable Development Goals (SDGs) call for a 90% reduction in tuberculosis deaths by 2030, compared with 2015, but meeting this target now seems highly improbable. To assess the economic impact of not meeting the target until 2045…
Pinto PFPS, Teixeira CSS, Ichihara MY, Rasella D, Nery JS, et al.
Background Although household contacts of patients with tuberculosis are known to be particularly vulnerable to tuberculosis, the published evidence focused on this group at high risk within the low-income and middle-income country context remains sparse. Using nationwide data fr…
Daniel W, Tadesse S, Tamirat T, Selamu M
Background The risk of tuberculosis transmission is higher among household contacts than the general population. However, there is a paucity of information that explains the risk of experiencing active tuberculosis among household contacts in countries with a high burden of tuber…
Shayan Shah, Michael Eisenhut
<b>Background:</b> Active tuberculosis has been associated with false negative interferon gamma release assay (IGRA) results. This may relate to a suppression of the interferon gamma response associated with a more extensive Mycobacterium (M.) tuberculosis infection. <b>Objective…
Jia Q, Masleša-Galić S, Nava S, Horwitz MA
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by the current Mycobacterium…
Ihor Dmytrovych Duzhyi, Г.П. Олещенко, Л.А. Бондаренко
The incidence of tuberculosis in our country, according to statistics, seems to be declining. However, it should be remembered that the figures of the Crimean Autonomous Republic and the temporarily occupied territories of Donetsk and Luhansk oblasts are excluded from the digital…
Bi D, Liang C, Huang X, Pan H, Qin Y, et al.
…ility of commercially available antibodies of Mycobacterium tuberculosis in the diagnostic assessment of suspected tuberculosis in high-burden countries. Methods We conducted a retrospective, descriptive, cohort study among participants aged ≥ 18 years with suspected tuberculosis…
Steven G Smith, Ruth Bowness, Jacqueline M Cliff
Host-directed therapy could potentially revolutionize tuberculosis control as an adjunct to traditional antibiotics for the treatment of tuberculosis disease and as a strategy to prevent disease progression following Mycobacterium tuberculosis infection. The growing type 2 diabet…
Lennard Meiwes, Irina Kontsevaya, Dumitru Chesov, Stela Kulciţkaia, Viola Dreyer, et al.
…ce mask sampling (FMS) confirmed detection of Mycobacterium tuberculosis DNA from exhaled breath in adults with tuberculosis. To date, no study has evaluated the use of FMS to detect pulmonary tuberculosis in children. We developed a method for FMS of M. tuberculosis-specific DNA…
Shivangi Sinhal, Geetika Srivastava, Shrish Bhatnagar, Nanda Chhavi, Digvijay Chaudhary, et al.
…ection is highly prevalent in our country and conversion to tuberculosis disease is a major concern. Under the National Strategic Plan, India is heading towards ending tuberculosis by 2025. The benefits of tuberculosis preventive therapy are being extended to the children aged &#…
Tangkat Friday Hosle
Tuberculosis is a communicable disease caused by Mycobacterium tuberculosis, considered a major risk to global health security. This study determined the prevalence, treatment outcomes, and factors associated with tuberculosis among 737 presumptive tuberculosis patients in Federa…
Meiwes L, Kontsevaya I, Chesov D, Kulciţkaia S, Dreyer V, et al.
…ce mask sampling (FMS) confirmed detection of Mycobacterium tuberculosis DNA from exhaled breath in adults with tuberculosis. To date, no study has evaluated the use of FMS to detect pulmonary tuberculosis in children. We developed a method for FMS of M. tuberculosis-specific DNA…
Puck T. Pelzer, Logan Stuck, Leonardo Martínez, Alexandra S Richards, Carlos Acuña-Villaorduña, et al.
BACKGROUND: Tuberculosis vaccine trials using disease as the primary endpoint are large, time consuming, and expensive. An earlier immunological measure of the protection against disease would accelerate tuberculosis vaccine development. We aimed to assess whether the effectivene…
Pelzer PT, Stuck L, Martinez L, Richards AS, Acuña-Villaorduña C, et al.
Background Tuberculosis vaccine trials using disease as the primary endpoint are large, time consuming, and expensive. An earlier immunological measure of the protection against disease would accelerate tuberculosis vaccine development. We aimed to assess whether the effectivenes…
G.I.A. Okoroiwu, Gloria I. Onokpise
Introduction: The occurrence of multi-drug resistance tuberculosis among tuberculosis patients has raised global public health concern, especially in Nigeria. The increase in the number of cases of resistance tuberculosis despite the effort and need to curb the menace in Nigeria …
Honjo K, Komiya K, Kan T, Uchida S, Goto A, et al.
…e advanced age is a main prognostic factor in patients with tuberculosis, the factors that specifically affect tuberculosis-related death are unclear because elderly people are at a risk for other age-related lethal diseases. We aimed to assess the impact of performance status on…
Jong Hoon Hyun, Myeongjee Lee, Inkyung Jung, Eun‐Hwa Kim, Seung Min Hahn, et al.
…cipients are immunocompromised and vulnerable to developing tuberculosis; however, active tuberculosis incidence is rapidly declining in South Korea. To evaluate the risk of developing active tuberculosis after transplantation, risk factors for tuberculosis and standardized incid…