Showing 76–100 of 172 documents
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Chalid MT, Puspawaty D, Tahir AM, Najdah H, Massi MN
…sitivity and specificity, respectively in detecting LTBI in pregnancy. Although there was a significant difference (P Conclusion TST assay is more sensitive than IGRA; however, the specificity of IGRA was superior to the TST method. In this study, a fair agreement of TST and IGRA…
Grace Chisale, Tiyamike Mwale, Chimwemwe Banda, Kondwani Phiri
…d synergistic health impacts of these conditions throughout pregnancy and the early postpartum period. Between March 2023 and February 2025, we enrolled 512 pregnant adolescents aged 15–19 from four antenatal clinics in Central and Southern Malawi. Participants underwent baseline…
Grace Chisale, Tiyamike Mwale, Chimwemwe Banda, Kondwani Phiri
…d synergistic health impacts of these conditions throughout pregnancy and the early postpartum period. Between March 2023 and February 2025, we enrolled 512 pregnant adolescents aged 15–19 from four antenatal clinics in Central and Southern Malawi. Participants underwent baseline…
DeAtley T, Hamada Y, Baddeley A, Werner P, Kanchar A, et al.
…s considerable variation between countries on the stages in pregnancy that TPT should be provided. Two countries (5%) provided clinical monitoring recommendations for pregnant women. CONCLUSIONS: There is moderate uptake of TPT policy for pregnant women with HIV. Failure to provi…
Layla Silveira, Williane Fernandes, A Monteiro, Livia Valle, Amanda Soares, et al.
…tal Tuberculosis (TB) is a rare disease, transmitted during pregnancy or postnatal. Its clinical presentation is similar to congenital infections and neonatal sepsis, thus, remains underestimated and underdiagnosed. CASE PRESENTATION: A 34 week female child, born vaginally, with …
Alex M. Chua, Jonathan Li, Justin S. Nichols, Kristen Facciolo
… countries, particularly immunocompetent patients. However, pregnancy is a risk factor for reactivation of latent tuberculosis and/or asymptomatic dissemination of primary tuberculosis. Case Description: A 17-year-old Guatemalan immigrant female, with recent history of spontaneou…
Rahman A, Thangaratinam S, Copas A, Zenner D, White PJ, et al.
… of reactivation of latent tuberculosis infection (LTBI) in pregnancy. The uptake of routine screening of migrants for LTBI in the UK in primary care is low. Antenatal care is a novel setting which could improve uptake and can lend insight into the feasibility and acceptability o…
Preeti F. Lewis, Amita Shankarrao Budhewar, Nitin Bavdekar, Deepika Gurnani, Ayushi Kumari
…rculosis as compared to pulmonary tuberculosis.Conclusions: Pregnancy with tuberculosis worsen the outcome of both mother and fetus. Our study depicted perinatal outcome is worse in Extrapulmonary TB than pulmonary TB. Atypical presentation of the Extrapulmonary TB may constitute…
Jansson L, Shedrawy J, Lönnroth K, Bruchfeld J, Kulane A
… OBJECTIVE: To explore how women diagnosed with LTBI during pregnancy understood and experienced their diagnosis and treatment. DESIGN: Sixteen semi-structured interviews with women on treatment for LTBI were analysed using content analysis with an inductive approach. RESULTS: No…
Fröberg G, Jansson L, Nyberg K, Obasi B, Westling K, et al.
…dence: 215/100 000). None had been screened for TB prior to pregnancy and only one had sought care due to symptoms.Systematic TB screening of pregnant women in Stockholm was feasible with a high yield of unknown LTBI and mostly asymptomatic active TB. Optimised routines improved …
Asgharzadeh V, Seyyed Rezaei SA, Asgharzadeh M, Rashedi J, Samadi Kafil H, et al.
…une system, diabetes, malignancy, malnutrition, anemia, and pregnancy. The risk factors contribute to the increase in TB cases through inflammation, increased contact with TB patients, disruption of immune genes, changes in gene expression, increased activity of Mtb, damage to ce…
Alana Pinheiro Alves, Denise Silva Araújo, George J Alangaden, Eloy E Ordaya
…dentifying one TB case. One patient received therapy during pregnancy, two others (3%) began treatment within the first six months post-partum. Rifampin was used in two patients and isoniazid in one, without significant side effects. One patient was diagnosed with active TB and b…
Mecha J, Escudero JN, Escudero JN, Richardson BA, Maleche-Obimbo E, et al.
…(QFT-Plus) and tuberculin skin tests (TST) at enrollment in pregnancy; children underwent TST at 12 and 24 months of age. We estimated the incidence and correlates of infant TST-positivity using Cox proportional hazards regression. Results Among 322 infants, 170 (53%) were HIV-ex…
Jay Phansalkar, Rajas Karajgikar, Jai Patel, Shauna Williams, Lisa Gittens-Williams, et al.
…ned due to the medical and social intricacies introduced by pregnancy. In this study, we evaluate the effectiveness of a screening intervention for LTBI in the prenatal clinic of an inner-city hospital in the United States, and analyze the cascade of care to identify areas for im…
Singh AP, Pramanik B, Tandon A, Krishna A, Seenu V
…years old, diagnosed with hypothyroidism, was evaluated for pregnancy loss and rapid weight gain from 13 years back and started on tablets of levothyroxine 25 µg once daily. She was doing well until the past 2 years; there after she noticed insidious onset of a swelling over ante…
Laborada J, Cohen PR
…r, it may be associated with drugs, infections, malignancy, pregnancy, and systemic illnesses. Erythema nodosum presents with the sudden onset of tender, warm, erythematous nodules typically on the ankles, knees, and shins. Although the pathogenesis has not been fully elucidated,…
Banerjee R, Sharma V, Patel R, Jena A, Pal P, et al.
…ure to tofacitinib should be avoided during pre-conception, pregnancy, and lactation. There is emerging evidence of tofacitinib in acute severe colitis, although the exact positioning (first-line with steroids or second-line) is uncertain.
Tasleem A, Mahmood A, Bharat A
…regnant females due to their immunosuppressed state. During pregnancy, the immune system is suppressed to prevent fetal rejection, and it gets reconstituted postpartum. During this reconstitution phase, reactivation of TB may occur, making it quintessential to test peripartum fem…
Chua A, Nichols J, Li JC, Flynn CE, Facciolo K
…, TB is a cause of spontaneous abortion. Conversely, during pregnancy, progesterone suppresses the T-helper 1 (Th1) proinflammatory response and increases susceptibility to TB. Peripartum women are at higher risk for disseminated TB, and postpartum women are twice as likely to ex…
Rockstrom M, Lutz R, Dickeson K, O'Rorke EV, Narita M, et al.
…race and genetic factors; (iii) age; (iv) body habitus; (v) pregnancy; and (vi) use of glucocorticoids.
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
…blood pressure, pulse rate, and respiration rate) and urine pregnancy test for women of childbearing potential, blood collection will be done in 300 eligible subjects for IGRA test, followed by C-TST skin test. Measure the body temperature of all subjects 30 min after the skin te…
Stephen A Migueles, M.D.
…l be referred for clinical care if needed. They will take a pregnancy test if needed. Participation will last from 2 days to 6 weeks. Study Description: This is a prospective study to compare the interferon-gamma release assay (IGRA) and tuberculin skin test (TST) as latent tu…
Galymzhan Togizbayev, Aigul Turtayeva, Gulzhan Gabdullina, Zharkynay Akhmetova, Bibikhan Eraliyeva
…lazine, glucocorticoids, and selected TNF inhibitors during pregnancy and lactation, while strictly avoiding teratogenic agents such as methotrexate and leflunomide. The QCR guidelines also encourage integration of RA management into Kazakhstan's national digital health strategy,…
Sailesh Shrestha
…h a history of active TB, immunocompromising conditions, or pregnancy. We collected demographic and clinical data through interviews, physical examinations, and medical record reviews. We screened all participants for TB symptoms; those with symptoms underwent chest X-ray and Gen…
Padmasayee Papineni
…ng for children with TB and women who have experience TB in pregnancy. Dissemination presentation to networks; deliver education sessions at temple, mosque, gurdwara. Partnerships Develop a network across the UK of a national TB community advisory group. Disclosures All Authors: …