Showing 76–100 of 200 documents
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Л. Н. Мотанова, M. N. Kudrya
…: to estimate the occurrence of clinical forms of childhood tuberculosis (TB) depending on BCG vaccination in regions with a high prevalence of TB. Materials and Methods . The research design is a retrospective continuous comparative study. We analyzed the data of registration fo…
D Connolly, Y Ammakola, M Glaser, O Niculescu
Abstract Introduction Reactivation of latent tuberculosis typically occurs as a result of initiation of immunosuppressive medications, HIV infection, malignancy, diabetes, or chronic kidney disease. Less commonly, reactivation TB can occur from severe malnutrition leading to lymp…
Yalçın Kara, Mahmut Can Kızıl, Merve İşeri Nepesov, Aslı Kavaz Tufan, Nuran Çetin, et al.
Purpose: Anti-TNF drugs increase the risk of tuberculosis. In this study we aimed to investigate the incidence of tuberculosis in patients using anti-TNF drugs.Methods: One hundred and fifteen pediatric cases which were received anti-TNF drugs were included in the study. The clin…
Comella-Del-Barrio P, Abellana R, Villar-Hernández R, Jean Coute MD, Sallés Mingels B, et al.
In recent years, pediatric research on tuberculosis (TB) has focused on addressing new biomarkers with the potential to be used as immunological non-sputum-based methods for the diagnosis of TB in children. The aim of this study was to characterize a set of cytokines and a series…
Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, et al.
…cians of Madrid (ICOMEM) regarding the current situation of tuberculosis, particularly in Spain. We have reviewed aspects such as the evolution of its incidence, the populations currently most exposed and the health care circuits for the care of these patients in Spain. We have a…
Azadeh Jafrasteh, Abdollah Karimi, Seyedeh Mahsan Hoseini‐Alfatemi, Leila Azimi, Payam Tabarsi, et al.
…are the most important diagnostic approach to Mycobacterium tuberculosis infection diagnosis. However, they cannot discriminate between latent tuberculosis infection (LTBI) and active tuberculosis (TB). Some recent studies suggested that interleukin-2 (IL-2) response to M. tuberc…
Zhang S, Li X, Chen H, Gao X, Cai Z, et al.
…mma (IFN-γ) release assay (IGRA) is an important laboratory diagnosis for latent Mycobacterium tuberculosis (TB) infection. The TB-IGRA measures the release of IFN-γ from peripheral blood cells, who are exposed to TB antigen (Ag), mitogen (MT), or negative/nil control (NL) in vit…
Lombardi G, Petrucci R, Corsini I, Bacchi Reggiani ML, Visciotti F, et al.
… of interferon gamma (IFN-γ) release assays (IGRAs) for the diagnosis of tuberculosis (TB) infection in children is still under debate because of concerns about the immature immune response in children. The aim of this study was to investigate quantitative values of the QuantiFER…
N. Belloumi, Mersni Meriem, Mechergui Najla, Mejda Bani, Nizar Ladhari, et al.
…care workers (HCWs) have an increased risk of Mycobacterium Tuberculosis (TB) infection compared to general population. Pregnancy suppresses the Lymphocyte T-helper 1 (Th1) pro-inflammatory response. Frequent and consecutive pregnancies may also promote TB infection or reactivati…
Mahsa Mohammadian, Saira Butt
…rare central nervous system manifestations of Mycobacterium tuberculosis (MTB), seen in only 1% of tuberculosis patients. It can manifest as single or multiple lesions, most commonly located in the frontal and parietal lobes. Clinical features are similar to any space-occupying l…
Dewi Oktavia Djasmi, Roza Kurniati, Fauzar
Background: Disseminated tuberculosis is defined as the involvement of two or more extrapulmonary organs due to Mycobacterium tuberculosis infection, which spreads hematogenously. Disseminated tuberculosis is a life-threatening condition, especially if diagnosis and treatment are…
Padghan Bhakti, Pol Shashikant Anil, Kulkarni Shreeya, Patel Rushika
Tuberculosis meningitis is an uncommon presentation and can vary from changes in behavior to neurological symptoms, including photophobia, headache, neck stiffness, limb weakness. It is relatively more common in patients who are immunocompromised, HIV (human immunodeficiency viru…
Dinara Adjablaeva
Latent tuberculosis infection is an asymptomatic condition in which patients carry the bacteria, but do not show any sign of illness, however they are at risk of disease activation at any time in the future. Understanding of influence of latent tuberculosis infection on the physi…
Saborni Dey, Siddarath Kumar, Vivek Tyagi, Venkata Sai Charan
Background: Tuberculosis (TB) is a serious illness that mainly affects the lungs. The Mantoux tuberculin skin test (TST) is one method of determining whether a person is infected with Mycobacterium tuberculosis. Reliable administration and reading of the TST requires standardizat…
Sun L, Qi X, Guo Y, Qi H, Li J, et al.
…ifying and prioritizing at-risk populations is critical for pediatric tuberculosis control. We aimed to identify a latent tuberculosis infection (LTBI) screening strategy that is appropriate for the Chinese context among children with different TB exposure levels and to explore i…
Ana Paula Pereira Guerra Franco, Ana Paula Quintanilha Dos Santos, Luis Guillermo Coca Velarde, Clemax Couto Sant'Anna, Claudete Aparecida Araújo Cardoso
…imated that 70 million children and adolescents have latent tuberculosis infection (LTBI) worldwide, thus representing an important reservoir of the disease. Diagnosis and prophylaxis of LTBI in this population remain a challenge because of social factors and barriers in contact …
Thomas Volkman, Hamish Graham, Ingrid Laemmle‐Ruff, Shidan Tosif, Marc Tebruegge, et al.
… (IGRA) is a perpetual challenge for those working in child tuberculosis (TB) and immigrant health services, and we commend the authors' attempt to provide guidance. However, we have a different interpretation of the study findings and the implications for practice and policy. As…
Andrea T. Cruz, Lee B. Reichman
…vention IGRA — : interferon γ release assay LTBI — : latent tuberculosis infection TST — : tuberculin skin test The Mantoux tuberculin test (TST) is likely the oldest widely used test in contemporary diagnostics. In the past, when its obvious weaknesses were considered, it always…
L. Duval, Poey Nora, Kheniche Ahmed, Grognet Essaian Alice, Assad Zein, et al.
…try and practitioners. With an incidence of 0.02% to 2% for tuberculosis disease (TBD) and 11% to 19% for latent tuberculosis (LTB) in migrant children, tuberculosis screening is considered a priority in the assessment of people coming from endemic countries,1 especially as the r…
Nur Sunar Yayla E, Yıldız Ç, Esmeray Şenol P, Karaçayır N, Gezgin Yıldırım D, et al.
… of this study is to analyze the adverse events observed in pediatric patients who received biological treatment. Materials and methods This retrospective observational cohort study was conducted between January 2010 and January 2022. File records of 139 patients used biological …
Özge Ülgen, Gülay Bilgin, Zeynep Reyhan Onay, Sinem Can Oksay, Deniz Mavi Tortop, et al.
<b>Introduction:</b> Mycobacterium tuberculosis, which causes tuberculosis (TB),is one of the most common infectious diseases in children and one of the main causes of morbidity and mortality in children. World Health Organization9s 2022 global TB report shows that COVID-19 outbr…
Soler-Garcia A, Gamell A, Monsonís M, Korta-Murua JJ, Espiau M, et al.
We studied 295 children (tuberculosis disease, n = 159; latent tuberculosis infection, n = 136) with positive QuantiFERON-TB Gold-Plus assay results. No significant differences between first and second antigen tube interferon-gamma responses were detected, irrespective of patient…
Ainharan Raveendran, Anish Keepanasseril, Ravi Kumar Balu, Ashalatha Shetty, Mahendran Chetty
Key content Tuberculosis (TB) is an important global cause of maternal and neonatal morbidity and mortality. With increasing migration, cases of tuberculosis in pregnancy or the puerperium are increasing in resource‐rich nations with advanced health care systems. Diagnosis may be…
Campbell JI, Tabatneck M, Sun M, He W, Musinguzi N, et al.
…lines recommend interferon gamma release assays (IGRAs) for diagnosis of tuberculosis infection in children. In this retrospective cohort study, IGRA use in children 2-17 years of age increased substantially between 2015 and 2021. Testing in inpatient/subspecialty settings (vs. p…
Gulyaeva N.A., Efremova E.P., Kasyanova A.M., Oshchepkova S.A
…or the detection and treatment of other diseases, including tuberculosis. A new coronavirus infection in children with respiratory tuberculosis and latent tuberculosis infection proceeds generally without complications, varying from asymptomatic to moderate. In children, there we…