Showing 76–100 of 200 documents
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Marks SM, Self JL, Venkatappa T, Wolff MB, Hopkins PB, et al.
…tion and control among PEH. Our goal was to provide current guidelines and information in one place to inform medical and public health providers and TB programs on TB incidence, diagnosis, and treatment among PEH. Methods We reviewed and synthesized diagnostic and treatment reco…
Valentina Aksenova, Nadezda Klevno, Alexey Kazakov, А. Д. Пахлавонова
…to WHO, the effectiveness of currently available preventive treatment schemes for people of the risk groups is from 60 to 90%. However, up to date, preventive treatment guidelines have not been developed for people who have been in contact with patients with MDR-TB. Objective of …
Pranay Sinha, Karen R. Jacobson, C. Robert Horsburgh, Benjamin P. Linas, Carlos Acuña-Villaorduña
Abstract Background Treatment for latent tuberculosis infection (LTBI) with rifampin and isoniazid is very effective but carries significant hepatotoxicity risks, increasing with age. Further, since the risk of progression to tuberculosis (TB) disease declines with increasing tim…
Sophie Forsyth, Tolulope Subuloluwa, Myat Lwin, Jessica Henderson Daniel
<h3>Introduction</h3> 2018 BHIVA Tuberculosis (TB) guidelines recommend testing people living with HIV (PLWH) from countries with high and medium TB incidence for LTBI and from low-incidence countries if they have additional TB risk factors. We had not yet introduced this in our …
Burguet L, Duvignaud A, Nguyen D, Receveur MC, Kaminski H, et al.
…rding to their level of priority. In those with evidence of latent TB infection, treatment decision was based on the level of exposure, individual vulnerability, as well as the results of an interferon-gamma release assay. Results A total of 130 patients with CKD and 180 KTR were…
James O’Connell, Eoghan de Barra, Cora McNally, Samuel McConkey
Aim Knowledge of latent tuberculosis infection (LTBI) screening and treatment practices are lacking in Ireland, where LTBI is not programmatically surveyed or managed. The aim of this research was to describe current clinical practice when screening and treating patients for LTBI…
Ling Chen, Lifan Zhang, Leidan Zhang, Liyuan Zheng, Jia Tang, et al.
…hain of anti-TB drugs, and insufficient understanding of TB treatment guidelines. China has always been regarded as a region with high TB burden. Therefore, conditional TB prophylaxis has been recommended in national guidelines for HIV-infected patients since 2006, with emphasis …
O'Connell J, de Barra E, McNally C, McConkey S
Aim Knowledge of latent tuberculosis infection (LTBI) screening and treatment practices are lacking in Ireland, where LTBI is not programmatically surveyed or managed. The aim of this research was to describe current clinical practice when screening and treating patients for LTBI…
Simon Tiberi, Giovanni Battista Migliori, Jeremiah Chakaya, Tereza Kaesava, Seif Al-Abri, et al.
…nd-tb.Google Scholar) to: scale up access to prevention and treatment; build a multisectorial accountability; ensure sufficient and sustainable financing including research; promote an end to stigma and discrimination, and promote an equitable, rights-based and people-centered TB…
Hashim Z, Tyagi R, Singh GV, Nath A, Kant S
…prevention of the development of active disease by treating latent TB infection (LTBI). The guidelines for the same were already provided by the WHO and were then adapted in the Indian guidelines for the treatment of LTBI in 2021. While the long-term impact of TBI treatment is aw…
Qiaoling Ruan, Jingyu Zhou, Shufeng Weng, Lingyun Shao, Wenhong Zhang
…leading cause of death among infectious diseases worldwide. Latent tuberculosis infections (LTBI) contribute to the global burden of TB disease. TB preventive treatment (TPT) is a key intervention to achieve the End TB Strategy targets. The World Health Organization recommends LT…
Miranda-Schaeubinger M, Derbew HM, Ramirez A, Smith M, Jalloul M, et al.
…the United States, positive PPD is sufficient to treat for "latent" TB, or TB infection in asymptomatic patients. Objective We sought to determine frequency of abnormal CXR findings after a positive purified protein derivative (PPD) test at a tertiary pediatric center in the Unit…
Godoy P
Objectives Latent TB infection (LTBI) affects 25% of the world's population. As long as this reservoir exists, the elimination of TB will not be feasible. The Assembly of the World Health Organization adopted the "Global End TB" strategy for the elimination of TB in 2014. The obj…
Bárbara Manuella Cardoso Sodré Alves, Melina Mafra Toledo, Ivan Ricardo Zimmermann, Wildo Navegantes de Araújo, Noêmia Urruth Leão Tavares
Background The treatment strategy for latent tuberculosis (TB) infection (LTBI) aims to promote a reduction in the number of cases that develop into TB and, consequently, a reduction in the transmission of pathogenic bacteria. Objectives The objective was to know the safety, effe…
Saurabh Dawra, Nipun Verma
…ients are immunosuppressed and are predisposed to flares of latent or incident infections.[1] Post-LT patients in India, a high burden country for tuberculosis(TB)[2] and liver disease-related immune dysfunction, are predisposed to acquire tubercular infections.[3] While treatmen…
Surve S, Naukariya K, Shah I
… review various studies conducted in relation to diagnosis, treatment and management of Latent TB Infection (LTBI) in under-five children, thus highlighting research gaps and further scope of improvements with respect to Indian context. The methodology involved literature review …
Daniel Yi Liang Tan, Young-Hoon Kim, Zeeshaan Hasan, Anthony Bewley, Sarah Mehrtens, et al.
… autoimmune dermatological conditions as an option if other treatments are unsuccessful or contraindicated. However, one major side-effect of biologics is immunosuppression, which may lead to the reactivation of latent tuberculosis (TB) in patients. The British Association of Der…
Awad SF, Critchley JA, Abu-Raddad LJ
… DM status, TB infection status and stage, TB disease form, treatment, recovery, and intervention status. Results By 2050, different TB vaccination strategies (coverage of 50 % and vaccine efficacies ranging between 50 %-60 %) reduced TB incidence and mortality rates by 4.5 %-20.…
Ajit Lalvani, Clementine Fraser, Manish Pareek
…at M.tb infection, even at very low bacterial burdens as in Latent tuberculosis infection (LTBI), evokes a strong Cell-mediated immunity response to M.tb antigens. LTBI was previously thought to represent a uniform state. However, as research progresses it has become clear that L…
Kim HW, Kim JS
The role of the treatment for latent tuberculosis infection (LTBI) has been underscored in the intermediate tuberculosis (TB) burden countries like South Korea. LTBI treatment is recommended only for patients at risk for progression to active TB-those with frequent exposure to ac…
University of Colorado, Denver
…eloping fetus. Additionally, women considering rifampin for treatment of LTBI face additional risks with an unintended pregnancy, making the reliability of contraception even more important for these women. The results of this study can directly inform counseling on a national an…
Wells C, Severn M
…rium Mycobacterium tuberculosis. Initial infection leads to latent TB, which has no active symptomology as the disease is contained by the host’s immune defences. However, in a small subset of infected patients (5% to 10%), the infection can proceed to active TB, which has visibl…
Song YJ, Cho SK, Kim H, Kim HW, Nam E, et al.
…f developing tuberculosis (TB). This requires diagnosis and treatment of latent tuberculosis infection (LTBI). We aimed to evaluate whether diagnosis and treatment of LTBI in RA are effective in Korea, and to estimate the risk of TB development by calculating the incidence rate o…
Li Y, Marks SM, Beeler Asay GR, Winston CA, Pepin D, et al.
…the United States, older adults have elevated prevalence of latent tuberculosis infection (LTBI) and incidence of tuberculosis (TB). Objective To estimate the health benefits and cost-effectiveness of LTBI testing and treatment among the Medicare-eligible population. Design Model…
Deborah Kirkham
<h3>Introduction</h3> National tuberculosis (TB) HIV guidelines published in 2018<sup>1</sup> recommend latent TB testing with interferon gamma-release assay (IGRA) in at-risk populations. <h3>Methods</h3> The HIV department liaised with the TB department to develop a referral pr…