Showing 51–75 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Rika Oktania Sari, Bayu Prabowo
Introduction: Pediatric tuberculosis can cause a variety of problems, including growth failure, disability, and death. In 2021, WHO recorded 10.6 million individuals had tuberculosis globally, with pediatric tuberculosis accounting for 11% of these cases. Indonesia is the second …
Nina T. Castillo-Carandang, Lauren M. Leining, Anna M. Mandalakas, Kristy O. Murray, Jinhua Liao, et al.
…r documents the experiences of rural physicians in managing pediatric tuberculosis (TB) cases before and after disasters in Bohol, Philippines. The participants are from the public and private healthcare systems in municipalities heavily affected and less affected by a 7.2-magnit…
E. S. Ovsyankinа, Л. В. Панова, И. Н. Захарова
Interdisciplinary interaction between phthisiatricians and pediatricians on the issues of detection and diagnosis of tuberculosis provides basis for the reduction of duration of the diagnostic process and the early identification of disease progression. The purpose of this review…
Sumona Datta, Carlton A. Evans
Tuberculosis is estimated to affect 10 million people each year, but this statistic is remarkably uncertain: 30% are countries' estimates of undiagnosed, untreated, or unreported cases. Furthermore, about half of tuberculosis diagnoses globally are uncertain because they rely ent…
Brendan Mullen, Joy Githua, Jaclyn N Escudero, Jerphason Mecha, Lucy Kijaro, et al.
Tuberculosis (TB) is a significant cause of morbidity and mortality in children and adolescents, causing 172,000 deaths in 2024 in children and adolescents worldwide. Diagnostic challenges are pronounced in pediatrics, in which collecting respiratory specimens is challenging and …
Laya BF, Concepcion NDP, Andronikou S, Abdul Manaf Z, Atienza MIM, et al.
Despite advances in diagnosis and treatment in recent years, tuberculosis (TB) remains a global health concern. Children are amongst the most vulnerable groups affected by this disease. Although TB primarily involves the lungs and mediastinal lymph nodes, it can affect virtually …
Marc d’Elbée, Nyashadzaishe Mafirakureva, Chishala Chabala, Minh Huyen Ton Nu Nguyet, Martin Harker, et al.
…ute malnutrition (SAM) are an important risk group for underdiagnosis and death from tuberculosis. In 2022, the World Health Organization (WHO) recommended use of treatment decision algorithms (TDAs) for tuberculosis diagnosis in children. There is currently no cost-effectiveness…
María I Urteneche, Norma E González, Eugenia Ginestet, Edith Macha Marín, Rosana Pereda, et al.
Introduction. Central nervous system tuberculosis (CNS TB) represents a severe form of Mycobacterium tuberculosis (Mtb) infection. Late diagnosis is associated with increased mortality and neurological sequelae. Objective. To characterize CNS TB diagnosed in a pediatric hospital …
Headriawan A, Pramono AA, Sukadi A, Chairulfatah A, Maskoen AM, et al.
Background As pediatric tuberculosis (TB) globally is still reported challenging in diagnosis, to date, a lot of efforts have been established to eliminate the disease including proper treatment regimen using anti-TB drugs. However, antituberculosis drug-induced hepatotoxicity (A…
Christiane Mello Schmidt, Claudete Aparecida Araújo Cardoso, Rafaela Baroni Aurílio, Maria de Fátima Bazhuni Pombo Sant’ Anna, Clemax Couto Sant’Anna
As children develop paucibacillary forms of tuberculosis (TB), bacteriological tests usually are negative. This chapter describes aspects of the laboratory tests available for clinical practicePractice. It also discusses perspectives, such as biomarkers, which can be utilized in …
Constantin Iavorschi, Stela Kulcitkaia, Igor Ivanes, Nadejda Pisarenco
Pediatric tuberculosis (TB) presents unique diagnostic challenges due to various factors, including the low sensitivity of sputum examination, difficulties in obtaining samples, and the presence of paucibacillary forms of the disease. This retrospective-descriptive study aimed to…
Babafemi EO, Cherian BP, Ouma B, Mogoko GM
Background Rapid and accurate diagnosis of paediatric tuberculosis (TB) is key to manage the disease and to control and prevent its transmission. Collection of quality sputum samples without invasion methods from paediatrics (age Methods We conducted a systematic review and meta-…
Maria Eugênia Julio, Alexandra Monteiro, Mônica de Cássia Firmida, Diego Rodrigues Tavares, Ana Josiele Ferreira Coutinho
Pulmonary tuberculosis in childhood is difficult diagnosis taking into account the difficulty of microbiological confirmation, being diagnosis based on the presence of clinical signs, radiological alterations, history of contact with a bacilliferous adult, and interpretation of t…
Sharma S, Shulania A, Achra A, Jeram H, Kansra S, et al.
… and Mycobacteria Growth Indicator Tube (MGIT™) culture for diagnosis of pediatric pulmonary tuberculosis from gastric aspirate (GA) samples and to compare Xpert assay and ZN staining with MGIT rapid liquid culture. Materials and methods GA samples from 210 nonexpectorating child…
Isabelle Munyangaju, Andreas Jahnen, Ridwaan Esmail, Benedita José, Jacinta Adrigwe, et al.
**BACKGROUND:** Pediatric tuberculosis diagnosis relies heavily on imaging, yet access, equipment standards, and dose monitoring differ widely across health systems. Evidence describing how these contextual factors influence imaging use and radiation exposure in children remains …
Aybüke Akaslan Kara, Kamile Ötiken Arıkan, Elif Böncüoğlu, Elif Kıymet, Şahika Şahinkaya, et al.
…we aimed to evaluate the approaches and knowledge levels of pediatric infectious diseases research workers and pediatricians in the diagnosis and treatment of tuberculosis under the guidelines updated by the Ministry of Health in 2019. Method: This survey is a descriptive study a…
Pierre-Louis MH, Rouzier V, Rivera V, Systrom HK, Julma P, et al.
… (Xpert) assay is a useful adjunct to culture for the rapid diagnosis of tuberculosis (TB) using gastric lavage aspirates (GLAs) in children aged Methods We reviewed the yield from diagnostic modalities in children suspected of having TB followed at an infectious disease research…
Olesya Pankratova
Tuberculosis is one of the 10 leading causes of death in the world. According to the WHO global strategy, one of the health targets of the Sustainable Development Goals is to end the tuberculosis epidemic by 2030. The article summarizes the basic theoretical data from various pro…
Tran ST, Le HT, Dang HTT, Dao TM, Van Nguyen L, et al.
Diagnosis of pediatric tuberculosis is notoriously difficult. We investigated the additional yield of blood culture in hospitalized children in Vietnam. Among 554 enrolled clinically suspected patients, an additional 6 cases were diagnosed, while the incremental cost per case was…
Villarreal EG, Ramos-Barrera E, Estrada-Mendizabal RJ, Treviño-Valdez PD, Tamez-Rivera O
…d Analyzing the epidemiology and clinical manifestations of pediatric tuberculosis in endemic regions is crucial to meet the goal of ending tuberculosis. The objective was to assess the various clinical scenarios of tuberculosis in a large pediatric cohort in Mexico. Methods This…
Gagni Coulibaly, Fah Gaoussou Traoré, Bassirou Diarra, Aminata Maïga
<h3>Background</h3> The diagnosis of childhood tuberculosis is still a challenge in the world because children are generally paucibacillary moreover obtaining sputum is very difficult. Most of the existing diagnostic tests for tuberculosis are based on sputum sampling in symptoma…
John Cherry
… Summary This preprint examines the time from completion of tuberculosis preventive therapy to later TB diagnosis among people living with HIV on ART in Eastern Uganda. The study uses routine program data from three TASO Centres of Excellence in Mbale, Soroti, and Tororo and incl…
John Cherry
… Summary This preprint examines the time from completion of tuberculosis preventive therapy to later TB diagnosis among people living with HIV on ART in Eastern Uganda. The study uses routine program data from three TASO Centres of Excellence in Mbale, Soroti, and Tororo and incl…
Christian Wejse
… al.Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation.Lancet Glob Health. 2019; 7: e798-e807Summary Full Text Full Text PDF PubMed Scopus (27) Google Scholar present a previou…
Enono Yhoshu, Deepak K Garnaik, Soumya Kashiv, Nowneet Bhat, Rajat Piplani, et al.
Aims Abdominal tuberculosis (TB) continues to be a common and challenging abdominal disease in children, with a nonspecific clinical presentation and poor outcomes in delayed diagnosis and complicated cases. We aimed to prospectively evaluate the clinical features and diagnostic …